Fundamental Toxicological Sciences

Paper Details

Fundamental Toxicological Sciences
Vol. 8 No. 2 May 21, 2021 p.49-52
Data Report
Acrylamide in dog food
  • Kazutoshi Sugita (School of Veterinary Medicine, Azabu University /
Kazutoshi Sugita 1) , Junpei Yamamoto 2) , Kimika Kaneshima 2) , Chika Kitaoka-Saito 2) , Masashi Sekimoto 2) , Osamu Endo 2) , Yukihiko Takagi 1) , Yuko Kato-Yoshinaga 2)
1) School of Veterinary Medicine, Azabu University , 2) School of Life and Environmental Science, Azabu University
Keywords: Acrylamide, Dog food, LC–MS/MS, Maillard reaction, QuEChERS

This study reported acrylamide, a carcinogenic substance produced by the Maillard reaction, in dog food, as a part of understand the mechanism of canine carcinogenesis. These results indicated that the average concentrations of acrylamide in dry, retort, and canned dog food were 39.6, 11.0, and 10.7 ng/g, respectively. Among the three, dry dog food exhibited significantly higher concentration. The daily intake of acrylamide by dogs was calculated to be 590 ng/kg/day, which is approximately four times higher than that of humans.