Fundamental Toxicological Sciences

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Fundamental Toxicological Sciences
Vol. 4 No. 1 February 24, 2017 p.23-29
Original Article
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
  • Kazutoshi Sugita (Laboratory of Veterinary Public Health, School of Veterinary Medicine, Azabu University / sugita@azabu-u.ac.jp)
Naoki Iwashita 1) , Kazutoshi Sugita 2) , Mitsuyuki Shirai 1) , Sayaka Murata 1) , Shiho Yanagisawa 2) , Sumio Goto 2) , Yukihiko Takagi 2) , Fumitoshi Asai 1)
1) Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University , 2) Laboratory of Veterinary Public Health, School of Veterinary Medicine, Azabu University
Keywords: Volatile sulfur compound, Portable gas chromatograph, Malodor, Periodontal disease, Dog
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Abstracts

Oral malodor is an unpleasant condition experienced by most individuals around the world. Volatile sulfur compounds (VSCs) may be the main source of oral malodor both in humans and dogs. The purpose of this study was to examine the suitability for measurement of oral malodor levels in dogs using OralChromaTM, a portable gas chromatograph developed for human use. Oral malodor and periodontal disease in laboratory Beagle dogs (N = 6) were determined by organoleptic assessment and OraStrip® test, respectively. Relatively high concentrations of VSCs in the breath were detected in all six dogs in the order of hydrogen sulfide (H2S) > methyl mercaptan (CH3SH) > dimethyl sulfide ((CH3)2S). There was no significant influence of meals on VSCs levels. Significant correlations (P < 0.05) were observed among each VSC. These findings for the first time highlight the potential of OralChromaTM, which allows for noninvasive, rapid and quantitative measurement of oral malodor levels in dogs, and warrants further investigation.

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