Paper Details
Fundamental Toxicological Sciences
Vol. 8
No. 2
May 21, 2021
p.49-52
Data Report
Acrylamide in dog food
- Kazutoshi Sugita (School of Veterinary Medicine, Azabu University / sugita@azabu-u.ac.jp)
Kazutoshi Sugita
1)
,
Junpei Yamamoto
2)
,
Kimika Kaneshima
2)
,
Chika Kitaoka-Saito
2)
,
Masashi Sekimoto
2)
,
Osamu Endo
2)
,
Yukihiko Takagi
1)
,
Yuko Kato-Yoshinaga
2)
1) School of Veterinary Medicine, Azabu University , 2) School of Life and Environmental Science, Azabu University
1) School of Veterinary Medicine, Azabu University , 2) School of Life and Environmental Science, Azabu University
Keywords: Acrylamide, Dog food, LC–MS/MS, Maillard reaction, QuEChERS
Abstracts
This study reported acrylamide, a carcinogenic substance produced by the Maillard reaction, in dog food, as a part of understand the mechanism of canine carcinogenesis. These results indicated that the average concentrations of acrylamide in dry, retort, and canned dog food were 39.6, 11.0, and 10.7 ng/g, respectively. Among the three, dry dog food exhibited significantly higher concentration. The daily intake of acrylamide by dogs was calculated to be 590 ng/kg/day, which is approximately four times higher than that of humans.