Paper Details
Fundamental Toxicological Sciences
Vol. 2
No. 6
December 21, 2015
p.239-243
Letter
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
- Akira Naganuma (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University / naganuma@m.tohoku.ac.jp)
Tsutomu Takahashi
1)
2)
,
Miyuki Iwai-Shimada
1)
,
Yukina Syakushi
1)
,
Min-Seok Kim
1)
,
Gi-Wook Hwang
1)
,
Nobuhiko Miura
3)
,
Akira Naganuma
1)
1) Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University , 2) Department of Environmental Health, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences , 3) Division of Health Effects Research, Japan National Institute of Occupational Safety and Health
1) Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University , 2) Department of Environmental Health, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences , 3) Division of Health Effects Research, Japan National Institute of Occupational Safety and Health
Keywords: Methylmercury, Brain, Interleukin, IL-1β, IL-19
Abstracts
We examined the effect of methylmercury administration on expression of interleukin genes in brain of mice. We found that gene expression of IL-1β and IL-19 was increased in the brain after the administration of methylmercury.