Fundamental Toxicological Sciences

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A

Akari Abe
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
Arislete Dantas de Aquino
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Asaka Arikawa
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Atsushige Ashimori
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
Auayporn Apirakaramwong
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Chihiro Amma
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Fumika Akizawa
2023 - Vol. 10 p.169-178
Toxicological effects of repeated subcutaneous administration of corn oil for 4 weeks in rats
Fumitoshi Asai
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
2018 - Vol. 5 p.13-20
Increased hepatic triglyceride level induced by a glucokinase activator in mice
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Haruyo Aoyagi
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Hermano Damasceno de Aquino
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Hideki Aizaki
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Hironori Aramaki
2017 - Vol. 4 p.195-200
Expression levels of 39 Cyp mRNAs in the mouse brain and neuroblastoma cell lines, C-1300N18 and NB2a – strong expression of Cyp1b1
2017 - Vol. 4 p.101-103
Phytocannabinoids, Δ9-tetrahydrocannabinol and cannabidiol, as human calpain-1 (CAPN1) activators
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
2016 - Vol. 3 p.55-61
HU-210, a synthetic analog of Δ9-THC, is not a modifier of estrogen signaling in MCF-7 human breast cancer cells
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
2015 - Vol. 2 p.233-238
(–)-Xanthatin-mediated marked up-regulation of RhoB, a sensor for damaged DNA
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Hiroshi Arakawa
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Hisae Aoshima
2021 - Vol. 8 p.123-133
Safety evaluation of 2-aza-8-oxohypoxanthine by in vitro skin sensitization and human tests
2020 - Vol. 7 p.207-214
Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests
Ikuyo Atsumi
2018 - Vol. 5 p.141-147
Anatomical and histological sex differences in the eye and its accessory tissues in Dutch belted rabbits
2016 - Vol. 3 p.217-232
Ocular instillation toxicity study: current status and points to consider on study design and evaluation
Jiro Akimoto
2015 - Vol. 2 p.111-116
Evaluation of laser irradiance on photodynamic therapy using talaporfin sodium-induced glioblastoma T98G cell death
Kayla Arizono
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Kazuhiko Aoyagi
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
Kazumasa Abe
2021 - Vol. 8 p.229-233
Time-dependent changes in serum concentrations of acyclovir and its metabolite, 9-carboxymethoxymethylguanine, in a patient with suspected acyclovir encephalopathy
Ken-ich Aisaki
2022 - Vol. 9 p.17-21
A novel high-purity carbon-nanotube yarn electrode used to obtain biopotential measurements in small animals: flexible, wearable, less invasive, and gel-free operation
Koji Arizono
2022 - Vol. 9 p.145-150
The effects on growth and reproductive function by parabens in C. elegans
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
2021 - Vol. 8 p.189-193
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Kumiko Anno
2022 - Vol. 9 p.47-59
Relationship between micronucleus formation and oxidative stress in human vascular endothelial cells under low dose rate irradiation
Mami Aoki
2014 - Vol. 1 p.63-72
A 4-week oral toxicity study of L-alanine in rats with a recovery period of 2 weeks
2014 - Vol. 1 p.49-62
A 13-week feeding toxicity study of L-threonine in rats with a recovery period of 5 weeks
Masahiro Akiyama
2020 - Vol. 7 p.161-166
Combined exposure to environmental electrophiles enhances cytotoxicity and consumption of persulfide
Masaki Asada
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Masato Asanuma
2017 - Vol. 4 p.37-39
Identification of transcription factors activated by methylmercury in mouse brain
Mathieu Anoy
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Miho Akatani
2017 - Vol. 4 p.1-7
Simultaneous depletion of WRNIP1 and RAD52 restores resistance to oxidative stress
Miho Arai
2022 - Vol. 9 p.85-93
Occupational exposure of pharmacists to drugs during tablet crushing and its countermeasures
Minori Awano
2020 - Vol. 7 p.281-286
Influence of skin condition on the skin penetration of dextran 4000 and ovalbumin
Naohiko Anzai
2023 - Vol. 10 p.259-264
Titanium dioxide and silica nanoparticles inhibit the efflux of adriamycin in multi-drug resistant L1210/ADM cells
Natacha Teresa Queiroz Alves
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Nobuo Aikawa
2017 - Vol. 4 p.167-171
Predicting clinical cardiotoxicity caused by trastuzumab and E-8010 using human cardiomyocytes
2017 - Vol. 4 p.127-136
The utility of human iPS cell-derived cardiomyocytes in predicting the clinical risk of drugs that display discordance of cardiotoxicity by species
Norio Akaike
2014 - Vol. 1 p.123-129
The paradoxical effect of 1,4-naphthoquinone on the process of cell death induced by hydrogen peroxide in rat thymocytes
Reo Anzai
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Rie Azuma
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
Ryosuke Akiyama
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Saori Akiduki
2019 - Vol. 6 p.65-74
Twenty-eight-day oral toxicity study of L-hydroxyproline in rats with 14-day post-treatment observation period
Shin Abe
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Sumiko Akiyoshi
2023 - Vol. 10 p.233-240
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
2022 - Vol. 9 p.151-157
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
2021 - Vol. 8 p.53-59
3’, 4’-Dihydroxyflavone enhances all-trans retinoic acid-induced superoxide-generating activity through up-regulating transcription of gp91-phox in human monoblastic U937 cells, as opposed to flavone and other hydroxyflavone derivatives
2019 - Vol. 6 p.319-325
Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells
Sylvester Addai-Arhin
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Takashi Ashino
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Takayuki Anzai
2020 - Vol. 7 p.105-114
Evaluation of cytokine storms in a disseminated intravascular coagulation monkey model
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Takuma Aoki
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
Takuya Aoshima
2016 - Vol. 3 p.1-8
Physiological conditions in iPRECIO® -implanted rats
Tetsuro Araki
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Tomoaki Araki
2023 - Vol. 10 p.199-208
Investigation of the maximum feasible volume of subretinal injections into rat and cynomolgus monkey eyes
2023 - Vol. 10 p.157-167
Evaluation of maximal dosing volume for intravitreal injections in cynomolgus monkeys
Toshi Akashi
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Toyohiko Aoki
2022 - Vol. 9 p.103-110
Fecal microRNA223 as an indicator of recovery in chronic DSS colitis model in rats
2021 - Vol. 8 p.177-182
Expression of miRNAs in the colon, rectum, plasma, and feces in rats with dextran sulfate sodium
2021 - Vol. 8 p.37-47
A 90-day oral repeated-dose toxicity study of Monascus Color Y-001 in rats
2021 - Vol. 8 p.7-16
Genotoxicity of Monascus Color Y-001
Yasuha Amano
2015 - Vol. 2 p.155-159
Effects of rofecoxib on lipid oxidation in plasma and aortas of rats
Yasumi Anan
2015 - Vol. 2 p.95-99
Metabolism of trimethylselenonium ion in selenium accumulator, Allium sativum
Yoshihiro Akimoto
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
Yoshiyuki Adachi
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
Yotaro Ando
2018 - Vol. 5 p.117-122
Chlorella supplementation decreases methylmercury concentrations of hair and blood in healthy volunteers
Yui Akagawa
2016 - Vol. 3 p.243-250
Safety assessment of probiotic bacteria, Bacillus coagulans strain SANK70258, in rats
Yukinori Amano
2014 - Vol. 1 p.39-47
Safety evaluation of morphological changes in corneal endothelial cells induced by K-115 in cynomolgus monkeys
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Yumi Abiko
2022 - Vol. 9 p.1-5
Glyceraldehyde 3-phosphate dehydrogenase converts methylmercury to its sulfur adduct with lowered toxicity through sulfane sulfur atoms on Cys247
Yumi Akahori
2023 - Vol. 10 p.287-293
Development of an in silico consensus model for predicting the chemical reactivity to cysteine measured by the DPRA and its application to predict the skin sensitization potential of chemicals
Yusuke Araki
2021 - Vol. 8 p.69-73
Evaluation of the in vitro cytotoxicity of oscillatoxins E and F under nutrient-starvation culture conditions
Yusuke Aratsu
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Yutaka Aoyagi
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice

B

Adrian Bull
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Alan B. Richards
2020 - Vol. 7 p.141-152
Maltosyltrehalose Syrup: Bacterial reverse mutation test, and 90-day feeding and 90-day repeated oral dose toxicity studies in rats
Jinhua Baoyindugurong
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Lia Belchior Mendes Bezerra
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Michael C. Babin
2016 - Vol. 3 p.195-204
Acute toxicity of phorate oxon by oral gavage in the Sprague-Dawley rat

C

Cheng Chen
2019 - Vol. 6 p.207-215
Procyanidin protects HK-2 cells against cisplatin-induced injury through antioxidant action involving Nrf2/HO-1 signaling pathway
Chi-Min Choi
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
David Coleman
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Emerson Chiu
2019 - Vol. 6 p.81-106
Genotoxicity and subchronic toxicity studies of Taiwanofungus camphoratus extract
Gaofeng Chen
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Horacio Cabral
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
Hyunjin Choi
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Jae-Hoon Choi
2020 - Vol. 7 p.207-214
Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests
Jin Cheng
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
Marcus Felipe Bezerra da Costa
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
Mei-Chun Chen
2019 - Vol. 6 p.81-106
Genotoxicity and subchronic toxicity studies of Taiwanofungus camphoratus extract
Mingliang Chen
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
Tamara C. Lopes de Castro
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Xuhong Chang
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats

D

Guorong Dan
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
Ke Du
2014 - Vol. 1 p.161-164
CDC23 knockdown reinforces methylmercury sensitivity in HEK293 cells
Masakuni Degawa
2022 - Vol. 9 p.167-172
Induction of CYP3A4 mRNA by cooked food-derived carcinogenic heterocyclic aromatic amines in human HPL-A3 cells
2014 - Vol. 1 p.169-172
Estimation of endoplasmic reticulum stress-inducing ability of nobiletin, a citrus polymethoxyflavonoid, in SK-N-SH human neuroblastoma cells
Osamu Doi
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Quang Phan Dinh
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Rodrigo Tavares Dantas
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
Wenwan Du
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Yuanyuan Deng
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
Yuko Doi
2021 - Vol. 8 p.37-47
A 90-day oral repeated-dose toxicity study of Monascus Color Y-001 in rats
2021 - Vol. 8 p.7-16
Genotoxicity of Monascus Color Y-001
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
2017 - Vol. 4 p.137-150
No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice
Yuya Deguchi
2022 - Vol. 9 p.173-178
Assessment of genotoxicity of 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) in zebrafish (Danio rerio) using the comet assay and micronucleus test

E

Chihiro Emori
2018 - Vol. 5 p.185-193
Study of metabolic activation of the UV-filter octyl methoxycinnamate for endocrine-disrupting activity
Frederick Adams Ekuban
2023 - Vol. 10 p.221-231
Effect of Anakinra (Kineret®) treatment on acrylamide-induced neurotoxicity in mice
Katsuhiro Esashika
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
María Elena Calderón-Segura
2021 - Vol. 8 p.81-88
Movento® 240SC (Spirotetramat) and Envidor® 240SC (Spirodiclofen) keto-enol insecticides induce DNA damage in Drosophila melanogaster ovaries
Osamu Endo
2021 - Vol. 8 p.49-52
Acrylamide in dog food
Takemi Enomoto
2017 - Vol. 4 p.1-7
Simultaneous depletion of WRNIP1 and RAD52 restores resistance to oxidative stress
Thomas Efferth
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish

F

Alzahraa Fergany
2023 - Vol. 10 p.221-231
Effect of Anakinra (Kineret®) treatment on acrylamide-induced neurotoxicity in mice
Atsushi Fujiwara
2020 - Vol. 7 p.105-114
Evaluation of cytokine storms in a disseminated intravascular coagulation monkey model
Chieri Fujino
2019 - Vol. 6 p.57-63
Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities
Eri Fukunaga
2015 - Vol. 2 p.217-222
Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes
2015 - Vol. 2 p.209-216
Zn2+-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-n-octyl-4-isothiazolin-3-one in rat thymocytes
2014 - Vol. 1 p.123-129
The paradoxical effect of 1,4-naphthoquinone on the process of cell death induced by hydrogen peroxide in rat thymocytes
Erika Furuta
2016 - Vol. 3 p.55-61
HU-210, a synthetic analog of Δ9-THC, is not a modifier of estrogen signaling in MCF-7 human breast cancer cells
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
Fumio Furukawa
2017 - Vol. 4 p.137-150
No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice
Hideki Fukuzumi
2014 - Vol. 1 p.49-62
A 13-week feeding toxicity study of L-threonine in rats with a recovery period of 5 weeks
Hirohisa Fujii
2017 - Vol. 4 p.261-268
Suppressive effect of Sasa veitchii extract on obesity induced by a high-fat diet through modulation of adipose differentiation in mice
Hitomi Fujishiro
2019 - Vol. 6 p.117-123
Gene expression profiles of immortalized S1, S2, and S3 cells derived from each segment of mouse kidney proximal tubules
Junichi Fujii
2023 - Vol. 10 p.325-333
Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Katsumi Fukamachi
2023 - Vol. 10 p.137-141
mRNA expression levels of CCL4, IL6, and CXCL2 in multiwalled carbon nanotube induced lung tumors in rats
2023 - Vol. 10 p.27-30
mRNA expression profile of cytokines in rat primary alveolar macrophages treated with multiwalled carbon nanotube (MWCNT)
Kenji Fukunaga
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Koki Fujimori
2014 - Vol. 1 p.87-94
Residual metals in carbon nanotubes suppress the proliferation of neural stem cells
Makiko Fujii
2020 - Vol. 7 p.281-286
Influence of skin condition on the skin penetration of dextran 4000 and ovalbumin
Masatake Fujimura
2021 - Vol. 8 p.243-248
Intake of wheat bran after administration of methylmercury reduces mercury accumulation in mice
Masatoshi Furukawa
2018 - Vol. 5 p.1-11
A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats
Mayumi Fujishiro
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Nanako Fukasawa
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Naomi Fujiwara
2021 - Vol. 8 p.183-187
Improvement of a fish holding device for oral administration to zebrafish
Nariaki Fujimoto
2018 - Vol. 5 p.185-193
Study of metabolic activation of the UV-filter octyl methoxycinnamate for endocrine-disrupting activity
Sakiko Fujii
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
2015 - Vol. 2 p.177-190
Repeated dose and reproductive/developmental toxicity of long-chain perfluoroalkyl carboxylic acids in rats: perfluorohexadecanoic acid and perfluorotetradecanoic acid
Sakura Fujiwara
2023 - Vol. 10 p.169-178
Toxicological effects of repeated subcutaneous administration of corn oil for 4 weeks in rats
2022 - Vol. 9 p.71-83
Genotoxicity and subchronic toxicity of a kaempferol aglycone-rich product produced from horseradish leaves
Sana Fujikawa
2021 - Vol. 8 p.17-22
Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15
Satoshi Fukushima
2022 - Vol. 9 p.145-150
The effects on growth and reproductive function by parabens in C. elegans
Satoshi Furukawa
2022 - Vol. 9 p.163-166
Comet assay of thyroid gland in rats treated with ethyl methanesulfonate
2018 - Vol. 5 p.167-170
Derivation of acceptable daily exposure value for alanine, N,N-bis(carboxymethyl)-, trisodium salt
Shiori Fukaya
2019 - Vol. 6 p.25-29
Protective effect of the Kampo formula “Juzen-taiho-to” on isoniazid- and rifampicin-induced hepatotoxicity in mice
2018 - Vol. 5 p.105-112
The Kampo formula “Juzen-taiho-to” exerts protective effects on ethanol-induced liver injury in mice
2016 - Vol. 3 p.233-236
Hepatoprotective effect of kampo formula “Juzen-taiho-to” on bromobenzene-induced toxicity in mice
Shoji Fukushima
2023 - Vol. 10 p.209-219
Subchronic oral toxicity study of Monascus Color in beagle dogs
Tomofumi Fujino
2024 - Vol. 11 p.11-15
Indeterminate alteration of TRPM8 and p21/Cip1 levels in normal human keratinocytes by incubating with medium including substances released by squamous carcinoma cells
2023 - Vol. 10 p.1-6
PPAR gamma negatively regulates the expression of TRPM8 in normal epidermal cells but mutually regulate their expressions with TRPM8 by feed-back loop regulation in squamous carcinoma cells
2021 - Vol. 8 p.17-22
Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15
2018 - Vol. 5 p.203-207
Cyclin-dependent kinase inhibitor p21/Cip1 down-regulates the expression of proteasome activator PA28γ in normal hepatocyte-derived cells
Tomoya Fujie
2018 - Vol. 5 p.181-184
A zinc complex that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
Toshihisa Fujiwara
2019 - Vol. 6 p.269-275
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys
Xi Feng
2019 - Vol. 6 p.207-215
Procyanidin protects HK-2 cells against cisplatin-induced injury through antioxidant action involving Nrf2/HO-1 signaling pathway
Xiao-Yu Fan
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Xinlu Fu
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Yasuyuki Fujiwara
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
2020 - Vol. 7 p.77-83
Arsenite inhibits gene expression of perlecan, syndecan-1, -2, -3 and biglycan in cultured vascular endothelial cells
2016 - Vol. 3 p.285-289
Sensitivity of MT-III null mice upon chronic exposure to cadmium
2015 - Vol. 2 p.111-116
Evaluation of laser irradiance on photodynamic therapy using talaporfin sodium-induced glioblastoma T98G cell death
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
2014 - Vol. 1 p.165-167
The involvement of GPRC5B in cadmium toxicity in HK-2 cells
2014 - Vol. 1 p.131-133
Effects of cadmium on the gene expression of SLC39A1 coding for ZIP1 protein
Yurika Fujita
2016 - Vol. 3 p.251-256
Validation of retrospective evaluation method for false genotoxic chemicals with strong cytotoxicity: re-evaluation using in vitro micronucleus test
Yuuki Fukai
2020 - Vol. 7 p.9-14
Usefulness and limitations of mRNA measurement in HepaRG cells for evaluation of cytochrome P450 induction

G

Akinori Gonsho
2014 - Vol. 1 p.29-38
28-Day dietary toxicity study of L-phenylalanine in rats
Berenyce González-Marín
2021 - Vol. 8 p.81-88
Movento® 240SC (Spirotetramat) and Envidor® 240SC (Spirodiclofen) keto-enol insecticides induce DNA damage in Drosophila melanogaster ovaries
Dioze Guadagnini
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
Fang Guo
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Jun Guo
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
Junjie Guo
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Keerthi S. Guruge
2014 - Vol. 1 p.101-108
Sex-dependent difference in the hepatic and pulmonary toxicological effects in mice administrated 7-chlorinated benz[a]anthracene
Keisuke Goda
2020 - Vol. 7 p.153-160
Usefulness of HepaRG cells in the mitochondrial function assay for the estimation of potential risk of idiosyncratic drug-induced liver injury
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
Luis Gerardo Moreno Ciénega
2021 - Vol. 8 p.81-88
Movento® 240SC (Spirotetramat) and Envidor® 240SC (Spirodiclofen) keto-enol insecticides induce DNA damage in Drosophila melanogaster ovaries
M. Gokila Vani
2016 - Vol. 3 p.205-216
In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)
Masashi Gamo
2014 - Vol. 1 p.1-6
Investigation of organ-specific assessment factors related to sub-acute and sub-chronic toxicity studies
Mayumi Goto
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Ming-Yu Gui
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
Sumio Goto
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
Toshinao Goda
2019 - Vol. 6 p.15-23
Supplementation with lower doses of EGCg reduces liver injury markers of type 2 diabetic rats
Xingchao Geng
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
Ya Gong
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply

H

Akihiko Hirose
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
2021 - Vol. 8 p.195-204
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
2019 - Vol. 6 p.327-332
Development of a hepatotoxicity prediction model using in vitro assay data of key molecular events
2019 - Vol. 6 p.125-136
Validation of the statistical parameters and model selection criteria of the benchmark dose methods for the evaluation of various endpoints in repeated-dose toxicity studies
2018 - Vol. 5 p.167-170
Derivation of acceptable daily exposure value for alanine, N,N-bis(carboxymethyl)-, trisodium salt
2018 - Vol. 5 p.75-82
Male-specific prolongation of prothombin time by industrial chemicals
2018 - Vol. 5 p.1-11
A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats
2017 - Vol. 4 p.247-259
Toxicity of repeated 28-day oral administration of acenaphthylene in rats
2017 - Vol. 4 p.207-218
Toxicity in repeated 28-day oral administration of N-phenyl-1-naphthylamine in rats
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
2015 - Vol. 2 p.177-190
Repeated dose and reproductive/developmental toxicity of long-chain perfluoroalkyl carboxylic acids in rats: perfluorohexadecanoic acid and perfluorotetradecanoic acid
2014 - Vol. 1 p.87-94
Residual metals in carbon nanotubes suppress the proliferation of neural stem cells
Akihiro Hagiwara
2023 - Vol. 10 p.209-219
Subchronic oral toxicity study of Monascus Color in beagle dogs
2021 - Vol. 8 p.37-47
A 90-day oral repeated-dose toxicity study of Monascus Color Y-001 in rats
Akira Hiratsuka
2019 - Vol. 6 p.107-112
Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction
Arisa Higa
2016 - Vol. 3 p.47-53
Differing responses of human stem cell-derived cardiomyocytes to arrhythmogenic drugs, determined using impedance measurements
Atsushi Hirata
2021 - Vol. 8 p.147-155
Relationship between renal dysfunction and change in serum electrolyte levels in patients administered with liposomal amphotericin B
Ayumi Hayashi
2018 - Vol. 5 p.21-32
Comparison of stabilities of nitrenium ions and in vitro and in vivo genotoxic potential, between four aniline derivatives
Dana Hoffmann
2018 - Vol. 5 p.167-170
Derivation of acceptable daily exposure value for alanine, N,N-bis(carboxymethyl)-, trisodium salt
Gi-Wook Hwang
2023 - Vol. 10 p.133-136
Effect of cadmium on expression of BIRC family genes in HeLa cells
2022 - Vol. 9 p.159-162
Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells
2021 - Vol. 8 p.157-160
Knockdown of deubiquitinating enzyme Usp34 confers resistance to methylmercury in HEK293 cells
2019 - Vol. 6 p.167-170
Methylmercury causes neuronal cell death via M1-microglial activation in organotypic slices prepared from mouse cerebral cortex
2019 - Vol. 6 p.113-116
Impairment of fertilization efficiency in mice following nano-sized titanium exposure
2018 - Vol. 5 p.93-97
Effect of heat shock protein gene expression on cadmium toxicity in human proximal tubular cells
2018 - Vol. 5 p.71-73
Putrescine selectively alleviates methylmercury toxicity in C17.2 mouse neural stem cells
2017 - Vol. 4 p.275-278
Effect of chronic cadmium exposure on the gene expression of Birc family in the mouse kidney and liver
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
2017 - Vol. 4 p.41-43
Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells
2017 - Vol. 4 p.37-39
Identification of transcription factors activated by methylmercury in mouse brain
2016 - Vol. 3 p.285-289
Sensitivity of MT-III null mice upon chronic exposure to cadmium
2016 - Vol. 3 p.281-284
Cadmium-induced protein ubiquitination in UBA80 knockdown HK-2 cells
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
2016 - Vol. 3 p.75-77
Overexpression of palmitoyl transferase HIP14 confers resistance to methylmercury in SH-SY5Y human neuroblastoma cells
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
2015 - Vol. 2 p.245-247
Knockdown of Acyl-CoA thioesterase 9 gene expression by siRNA confers resistance to arsenite in HEK293 cells
2015 - Vol. 2 p.239-243
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
2015 - Vol. 2 p.229-231
Citrulline enhances methylmercury toxicity in HEK293 and C17.2 cells
2015 - Vol. 2 p.227-228
Metabolomic analysis of low molecular weight substances released into medium from HEK293 cells treated with methylmercury
2015 - Vol. 2 p.223-226
Methylmercury induces release of a cytotoxic factor from HEK293 cells into medium
2014 - Vol. 1 p.161-164
CDC23 knockdown reinforces methylmercury sensitivity in HEK293 cells
2014 - Vol. 1 p.113-114
Identification of growth-dependent genes involved in paraquat toxicity in Saccharomyces cerevisiae
2014 - Vol. 1 p.109-111
Overexpression of RPN8, SKP1, MIA40 or MES1 increases resistance to cadmium in Saccharomyces cerevisiae
2014 - Vol. 1 p.95-99
A screening method for growth-dependent genes involved in the cytotoxicity of chemicals in Saccharomyces cerevisiae
Haruka Hino
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Hirokazu Honda
2021 - Vol. 8 p.229-233
Time-dependent changes in serum concentrations of acyclovir and its metabolite, 9-carboxymethoxymethylguanine, in a patient with suspected acyclovir encephalopathy
Hiromi Hagiwara
2019 - Vol. 6 p.249-252
Localization of the trichloroethylene-related compound S-(1, 2-dichlorovinyl)-L-cysteine in mouse cartilage
Hiroshi Honda
2016 - Vol. 3 p.251-256
Validation of retrospective evaluation method for false genotoxic chemicals with strong cytotoxicity: re-evaluation using in vitro micronucleus test
Hirotaka Hoshi
2016 - Vol. 3 p.47-53
Differing responses of human stem cell-derived cardiomyocytes to arrhythmogenic drugs, determined using impedance measurements
Ikue Hayashi
2022 - Vol. 9 p.47-59
Relationship between micronucleus formation and oxidative stress in human vascular endothelial cells under low dose rate irradiation
Izumi Hirayama
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
Jo Hatogai
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Junji Hosokawa-Muto
2019 - Vol. 6 p.187-195
Oral toxicity study of an antiprion compound N,N’-[(cyclohexylmethylene)di-4,1-phenylene]bis[2-(1-pyrrolidinyl) acetamide] in rats and cynomolgus monkeys
Kaname Hashizaki
2020 - Vol. 7 p.281-286
Influence of skin condition on the skin penetration of dextran 4000 and ovalbumin
Kaori Harata
2023 - Vol. 10 p.233-240
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
2022 - Vol. 9 p.151-157
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
2021 - Vol. 8 p.53-59
3’, 4’-Dihydroxyflavone enhances all-trans retinoic acid-induced superoxide-generating activity through up-regulating transcription of gp91-phox in human monoblastic U937 cells, as opposed to flavone and other hydroxyflavone derivatives
2020 - Vol. 7 p.201-206
Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
Kato Hina
2015 - Vol. 2 p.177-190
Repeated dose and reproductive/developmental toxicity of long-chain perfluoroalkyl carboxylic acids in rats: perfluorohexadecanoic acid and perfluorotetradecanoic acid
Katsuyoshi Horibata
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
Kazuhisa Hatayama
2014 - Vol. 1 p.63-72
A 4-week oral toxicity study of L-alanine in rats with a recovery period of 2 weeks
Kazuma Higashisaka
2017 - Vol. 4 p.109-119
Permeability of skin to silver nanoparticles after epidermal skin barrier disruption in rats
Kenji Hattori
2024 - Vol. 11 p.27-35
Development of an in vivo pain assessment method for exposure to intermediate-frequency magnetic fields
Kiyohiro Hashimoto
2023 - Vol. 10 p.307-313
Derivation of permitted daily exposure value for trifluoroacetic acid as an impurity in pharmaceutical products
2023 - Vol. 10 p.301-306
Derivation of the permitted daily exposure value for p-tert-butylphenol as an impurity in pharmaceutical products
2023 - Vol. 10 p.295-300
Derivation of permitted daily exposure value for 1,8-diazabicyclo[5.4.0]undec-7-ene in pharmaceutical products
Makio Hayakawa
2021 - Vol. 8 p.17-22
Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15
2018 - Vol. 5 p.203-207
Cyclin-dependent kinase inhibitor p21/Cip1 down-regulates the expression of proteasome activator PA28γ in normal hepatocyte-derived cells
Masaharu Hisasue
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
Masahiro Hosonuma
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Masami Hori
2020 - Vol. 7 p.133-139
Sex differences in the effects of high-fat diet on mouse sciatic nerves
Masashi Hiramoto
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
Masayo Hirao-Suzuki
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Miho Hirata
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Miwa Harada
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Motoki Hojo
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Mutsuko Hirata-Koizumi
2019 - Vol. 6 p.125-136
Validation of the statistical parameters and model selection criteria of the benchmark dose methods for the evaluation of various endpoints in repeated-dose toxicity studies
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
2015 - Vol. 2 p.177-190
Repeated dose and reproductive/developmental toxicity of long-chain perfluoroalkyl carboxylic acids in rats: perfluorohexadecanoic acid and perfluorotetradecanoic acid
Nana Hirota
2022 - Vol. 9 p.145-150
The effects on growth and reproductive function by parabens in C. elegans
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Natsuyo Hariya
2019 - Vol. 6 p.235-243
High-dose β-carotene exacerbates high-fat/high-sucrose diet-inducible fibrosis in the liver of Mongolian gerbils
2019 - Vol. 6 p.15-23
Supplementation with lower doses of EGCg reduces liver injury markers of type 2 diabetic rats
Noriko Hayashi
2021 - Vol. 8 p.23-31
The influence of long-term ingestion of D-allulose in hypercholesterolemia patients under statin therapy
2020 - Vol. 7 p.15-31
Safety and efficacy of a 48-week long-term ingestion of D-allulose in subjects with high LDL cholesterol levels
2019 - Vol. 6 p.225-234
Safety evaluation of 12-week continuous ingestion of D-allulose in borderline diabetes and type 2 diabetes
Norio Hirayama
2019 - Vol. 6 p.333-340
Assessment of the acute toxicity of 16 veterinary drugs and a disinfectant to aquatic and soil organisms
Nozomi Hagihara
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
Nozomu Hirose
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
Rieko Hojo
2015 - Vol. 2 p.249-258
Developmental changes in associative learning behavior in male rats
2014 - Vol. 1 p.135-142
Effects of a repeated low dose of LiCl injection under conditioned taste/flavor aversion using xylene
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Ryota Hosomi
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Ryuichi Hasegawa
2018 - Vol. 5 p.75-82
Male-specific prolongation of prothombin time by industrial chemicals
Saori Hagiwara
2016 - Vol. 3 p.27-31
Quantitative analysis of the relationship between the LLNA:DAE method results and the LLNA EC3 values highlights the connection between the elicitation and induction phases during skin sensitization
Sari Honda
2015 - Vol. 2 p.209-216
Zn2+-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-n-octyl-4-isothiazolin-3-one in rat thymocytes
Sayaka Himuro
2014 - Vol. 1 p.151-159
Safety evaluation of mutagenecity, acute and subacute toxicity study of Chlorella vulgaris CK-22 in rats
Sayuri Hyodo
2020 - Vol. 7 p.207-214
Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests
Seiichiro Himeno
2019 - Vol. 6 p.117-123
Gene expression profiles of immortalized S1, S2, and S3 cells derived from each segment of mouse kidney proximal tubules
Seiko Hashiguchi
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Shim-mo Hayashi
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Shohei Harada
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Shoko Hattori
2019 - Vol. 6 p.57-63
Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities
Soichiro Hagio
2022 - Vol. 9 p.163-166
Comet assay of thyroid gland in rats treated with ethyl methanesulfonate
Su-Cheol Han
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Takaharu Hashimoto
2020 - Vol. 7 p.141-152
Maltosyltrehalose Syrup: Bacterial reverse mutation test, and 90-day feeding and 90-day repeated oral dose toxicity studies in rats
2019 - Vol. 6 p.299-317
Glucosyl hesperidin: safety studies
Takashi Hirota
2015 - Vol. 2 p.155-159
Effects of rofecoxib on lipid oxidation in plasma and aortas of rats
Takato Hara
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
2018 - Vol. 5 p.181-184
A zinc complex that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
Takayuki Hoshi
2019 - Vol. 6 p.167-170
Methylmercury causes neuronal cell death via M1-microglial activation in organotypic slices prepared from mouse cerebral cortex
Takeshi Honma
2018 - Vol. 5 p.153-159
In utero exposure to 2,2’,4,4’,5,5’-hexachlorobiphenyl accelerates the onset of eye opening in rat offspring
Takuro Hasegawa
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
Takuya Honda
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Tatsuya Hasegawa
2019 - Vol. 6 p.113-116
Impairment of fertilization efficiency in mice following nano-sized titanium exposure
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Toshiki Homma
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Toshiyuki Higuchi
2023 - Vol. 10 p.265-277
Differential expression of Cytochrome P450 1A2 in simple fatty liver and steatohepatitis
2022 - Vol. 9 p.187-196
Pharmaceutical concentrations and antimicrobial activity using hypersusceptible Escherichia coli lacking TolC component of multidrug efflux system in the Ayase River in Japan
2022 - Vol. 9 p.85-93
Occupational exposure of pharmacists to drugs during tablet crushing and its countermeasures
Xiaobo Han
2022 - Vol. 9 p.203-209
An in vitro microfluidic culture device for peripheral neurotoxicity prediction at low concentrations based on deep learning
Xu Hai-bin
2015 - Vol. 2 p.9-17
Effects of sub-chronic exposure to deltamethrin on shuttle-box avoidance and contents of amino acid neurotransmitters in hippocampus of mice
Yanfeng Huang
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Yanping Hu
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Yasunori Hase
2018 - Vol. 5 p.21-32
Comparison of stabilities of nitrenium ions and in vitro and in vivo genotoxic potential, between four aniline derivatives
Yasushi Hirota
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Yoko Hashimoto
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Yoko Hashizume
2014 - Vol. 1 p.115-121
Diallyl disulfide administration increases the number of B-lymphocytes in the rat spleen
Yoko Hirabayashi
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
Yoshitaka Hirasawa
2020 - Vol. 7 p.105-114
Evaluation of cytokine storms in a disseminated intravascular coagulation monkey model
Youhei Hiromori
2022 - Vol. 9 p.25-30
Erratum: Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2017 - Vol. 4 p.121-126
Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
Yu Haranosono
2023 - Vol. 10 p.295-300
Derivation of permitted daily exposure value for 1,8-diazabicyclo[5.4.0]undec-7-ene in pharmaceutical products
2023 - Vol. 10 p.249-258
Survey of toxicity study packages and designs of intravitreal drugs approved in Japan
2023 - Vol. 10 p.105-112
A survey of on the use of genotoxicity and carcinogenicity testing packages for ophthalmic drug development
2017 - Vol. 4 p.105-107
A study for finding new phototoxicity descriptors related to potential energy
2017 - Vol. 4 p.95-99
Repeated-dose ocular instillation toxicity study: a survey of its study design on the basis of common technical documents in Japan
Yuhzo Hieda
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Yuji Hashimoto
2015 - Vol. 2 p.209-216
Zn2+-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-n-octyl-4-isothiazolin-3-one in rat thymocytes
Yukiko Hoshino
2017 - Vol. 4 p.241-245
In vitro genotoxicity test package of antibiotics for human use submitted to the Japanese regulatory agency during 2004–2015
Yukio Hitotsuyanagi
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
Yusuke Hanaki
2021 - Vol. 8 p.69-73
Evaluation of the in vitro cytotoxicity of oscillatoxins E and F under nutrient-starvation culture conditions
Yuta Honma
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
Zhiying Huang
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts

I

Akiko Ido
2022 - Vol. 9 p.25-30
Erratum: Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2017 - Vol. 4 p.121-126
Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
Akiko Inomata
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Atsuto Inoue
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Ayaka Ikeda
2014 - Vol. 1 p.169-172
Estimation of endoplasmic reticulum stress-inducing ability of nobiletin, a citrus polymethoxyflavonoid, in SK-N-SH human neuroblastoma cells
Fumie Itoh
2023 - Vol. 10 p.241-247
Effects of expression of the 10-formyltetrahydrofolate metabolizing enzyme ALDH1L1 on pyrimidine nucleotide synthesis and the salvage pathway
Gaku Ichihara
2023 - Vol. 10 p.221-231
Effect of Anakinra (Kineret®) treatment on acrylamide-induced neurotoxicity in mice
2018 - Vol. 5 p.167-170
Derivation of acceptable daily exposure value for alanine, N,N-bis(carboxymethyl)-, trisodium salt
Hajime Imai
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
Hayato Irokawa
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
Hidefumi Ikeda
2022 - Vol. 9 p.117-122
Leaf extracts from Camellia sinensis and Argania spinosa suppress oxidative stress and chemokine release in human 3-dimensional cultured epidermis exposed to PM2.5 collected with cyclonic separation
Hijiri Iwata
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Hiroshi Ikegami
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023
Hiroshi Ishibashi
2021 - Vol. 8 p.189-193
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Hiroshi Itagaki
2023 - Vol. 10 p.113-123
A trial to predict skin irritancy of cosmetic products using cytotoxicity tests
2016 - Vol. 3 p.27-31
Quantitative analysis of the relationship between the LLNA:DAE method results and the LLNA EC3 values highlights the connection between the elicitation and induction phases during skin sensitization
Hirotaro Iwase
2021 - Vol. 8 p.61-67
Effects of hemoglobin on post-mortem oxidation of bromazepam
Hiroyasu Ito
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Hiroyuki Ishii
2016 - Vol. 3 p.55-61
HU-210, a synthetic analog of Δ9-THC, is not a modifier of estrogen signaling in MCF-7 human breast cancer cells
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
Hisakazu Iwai
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Isao Ishida
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Kaoru Inoue
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
2019 - Vol. 6 p.145-165
Comprehensive toxicity evaluation of cyclopentyl methyl ether (CPME) for establishing a permitted daily exposure level
Katsuharu Iwadate
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
Katsuhiro Isoda
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Katsumi Iwabuchi
2015 - Vol. 2 p.201-208
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient
Kazuhiko Imaizumi
2014 - Vol. 1 p.115-121
Diallyl disulfide administration increases the number of B-lymphocytes in the rat spleen
Kazuma Iwatate
2015 - Vol. 2 p.55-60
Metabolic fate of excessive glucose in fibroblast cells in a diabetic setting
Kazuo Isama
2021 - Vol. 8 p.205-213
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity
Keiko Ichimura
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
Keishi Ishida
2020 - Vol. 7 p.33-40
Triphenyltin inhibits GA-binding protein α nuclear translocation
Kenji Iida
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
Kimiyoshi Ichida
2022 - Vol. 9 p.197-202
Transient increase in plasma urate induced by a single oral dose of fructose in rats
Kiyomi Ikushima
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Kousei Ito
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Masami Ishido
2022 - Vol. 9 p.111-115
De novo transgenerational inheritance of male rat hyperactivity by rotenone
2020 - Vol. 7 p.253-257
Electromagnetic fields (EMF) facilitate cell migration and BrdU incorporation during an EMF-sensitive phase in a rat neurosphere assay in vitro
2019 - Vol. 6 p.277-279
A carrier protein is essential for the action of silver nanoparticles in an animal experiment
2018 - Vol. 5 p.195-202
The temporal turning window for rat behavioral phenotypes by rotenone
2017 - Vol. 4 p.191-193
A new insight into proliferative action of bisphenol A at low-dose
2017 - Vol. 4 p.187-189
HSP70-Ran-RCC1 transport system during cadmium-induced apoptosis in porcine kidney LLC-PK1 cells
2017 - Vol. 4 p.159-165
Distinct regulation of nuclear localization of caspase-activated DNase during cadmium-induced apoptosis of the target cells
2017 - Vol. 4 p.151-158
Orally administered p-nitrotoluene causes hyperactivity, concomitant with gliosis and impairment of tyrosine hydroxylase immunoreactivity in the rat substantia nigra
2016 - Vol. 3 p.101-108
Major histocompatibility complex expression in a rotenone model of Parkinson’s disease in rats
Masaru Irie
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Masaya Ito
2019 - Vol. 6 p.333-340
Assessment of the acute toxicity of 16 veterinary drugs and a disinfectant to aquatic and soil organisms
2017 - Vol. 4 p.207-218
Toxicity in repeated 28-day oral administration of N-phenyl-1-naphthylamine in rats
Masayuki Ikeda
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
Midori Iida
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Miko Imai
2020 - Vol. 7 p.281-286
Influence of skin condition on the skin penetration of dextran 4000 and ovalbumin
Mitsuharu Ishida
2015 - Vol. 2 p.67-78
Effect of prenatal methylmercury exposure on neurobehavioral development in male mice: comparison between methylmercury in fish and methylmercury chloride added to diets
Miyuki Iwai-Shimada
2015 - Vol. 2 p.239-243
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
2015 - Vol. 2 p.67-78
Effect of prenatal methylmercury exposure on neurobehavioral development in male mice: comparison between methylmercury in fish and methylmercury chloride added to diets
2014 - Vol. 1 p.161-164
CDC23 knockdown reinforces methylmercury sensitivity in HEK293 cells
Mutsumi Inamatsu
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Nami Ishihara
2022 - Vol. 9 p.117-122
Leaf extracts from Camellia sinensis and Argania spinosa suppress oxidative stress and chemokine release in human 3-dimensional cultured epidermis exposed to PM2.5 collected with cyclonic separation
Naohiro Imura
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Naoki Ishida
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Naoki Ishiguro
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Naoki Iwashita
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
Naoko Ikoma
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
Nobuhiro Ichikawa
2022 - Vol. 9 p.145-150
The effects on growth and reproductive function by parabens in C. elegans
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
Norihiko Iwazaki
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Norio Imai
2021 - Vol. 8 p.37-47
A 90-day oral repeated-dose toxicity study of Monascus Color Y-001 in rats
2021 - Vol. 8 p.7-16
Genotoxicity of Monascus Color Y-001
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
2017 - Vol. 4 p.137-150
No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice
Rika Iwamoto
2018 - Vol. 5 p.63-69
Assessment of bladder DNA damage due to 2-acetylaminofluorene, diuron, and terephthalic acid by the rat comet assay
Rinta Ibuki
2021 - Vol. 8 p.123-133
Safety evaluation of 2-aza-8-oxohypoxanthine by in vitro skin sensitization and human tests
2020 - Vol. 7 p.207-214
Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests
Ryo Inagaki
2019 - Vol. 6 p.9-14
Investigation of DNA damage of glycidol and glycidol fatty acid esters using Fpg-modified comet assay
Ryota Ise
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Seiichi Ishida
2020 - Vol. 7 p.9-14
Usefulness and limitations of mRNA measurement in HepaRG cells for evaluation of cytochrome P450 induction
Shigeru Ishida
2014 - Vol. 1 p.49-62
A 13-week feeding toxicity study of L-threonine in rats with a recovery period of 5 weeks
Shin-ichiro Inoue
2022 - Vol. 9 p.23-23
Erratum: Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
2017 - Vol. 4 p.57-75
Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
Shingo Iwasa
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
Shinobu Imajoh-Ohmi
2016 - Vol. 3 p.137-142
GCN5-deficiency remarkably enhances the sensitivity of B cells in response to 4-nitroquinoline 1-oxide
Shiro Ishida
2015 - Vol. 2 p.209-216
Zn2+-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-n-octyl-4-isothiazolin-3-one in rat thymocytes
2014 - Vol. 1 p.123-129
The paradoxical effect of 1,4-naphthoquinone on the process of cell death induced by hydrogen peroxide in rat thymocytes
Shota Inoue
2016 - Vol. 3 p.121-125
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes
Tadashi Imamura
2019 - Vol. 6 p.367-382
Safety evaluation of chicken breast meat extract in chromosomal aberration study, reverse mutation test, and 90-day repeated dose study in rats
Tadashi Izawa
2019 - Vol. 6 p.107-112
Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction
Takahiro Ishii
2021 - Vol. 8 p.7-16
Genotoxicity of Monascus Color Y-001
Takako Iso
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
2018 - Vol. 5 p.1-11
A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats
Takayoshi Imazawa
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Takeshi Iijima
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
Takuma Iguchi
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Takuya Izumi
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Tetsuo Iida
2021 - Vol. 8 p.23-31
The influence of long-term ingestion of D-allulose in hypercholesterolemia patients under statin therapy
2020 - Vol. 7 p.15-31
Safety and efficacy of a 48-week long-term ingestion of D-allulose in subjects with high LDL cholesterol levels
2019 - Vol. 6 p.225-234
Safety evaluation of 12-week continuous ingestion of D-allulose in borderline diabetes and type 2 diabetes
2019 - Vol. 6 p.217-224
Recovery of increased weights of the liver and kidneys by cessation of D-allulose feeding in Wistar rats
Tetsuro Ito
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Tomio Ishida
2017 - Vol. 4 p.9-14
Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs
Tomoaki Inoue
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Tomohiko Irie
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Tomoko Inubushi
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Toshime Igarashi
2023 - Vol. 10 p.69-82
A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
2023 - Vol. 10 p.59-68
A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
2018 - Vol. 5 p.75-82
Male-specific prolongation of prothombin time by industrial chemicals
2018 - Vol. 5 p.1-11
A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats
2017 - Vol. 4 p.247-259
Toxicity of repeated 28-day oral administration of acenaphthylene in rats
Wataru Ishikawa
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
Yasuhiro Ishibashi
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Yasuhiro Ishihara
2022 - Vol. 9 p.117-122
Leaf extracts from Camellia sinensis and Argania spinosa suppress oxidative stress and chemokine release in human 3-dimensional cultured epidermis exposed to PM2.5 collected with cyclonic separation
2016 - Vol. 3 p.63-65
Transcription factor activation in rat primary astrocytes exposed to methylmercury
Yoshiaki Ikarashi
2014 - Vol. 1 p.87-94
Residual metals in carbon nanotubes suppress the proliferation of neural stem cells
Yoshihiko Ito
2019 - Vol. 6 p.333-340
Assessment of the acute toxicity of 16 veterinary drugs and a disinfectant to aquatic and soil organisms
Yugo Ikeyama
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Yuichi Ito
2016 - Vol. 3 p.251-256
Validation of retrospective evaluation method for false genotoxic chemicals with strong cytotoxicity: re-evaluation using in vitro micronucleus test
Yuki Inoue
2023 - Vol. 10 p.169-178
Toxicological effects of repeated subcutaneous administration of corn oil for 4 weeks in rats
Yuki Ishida
2022 - Vol. 9 p.23-23
Erratum: Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
2017 - Vol. 4 p.57-75
Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
Yuki Ito
2017 - Vol. 4 p.201-205
Organophosphorus insecticide dichlorvos inhibits fatty acid amide hydrolase in the male reproductive organs of rats
Yukiko Inoue
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Yumiko Iwase
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals

J

David A. Jett
2016 - Vol. 3 p.195-204
Acute toxicity of phorate oxon by oral gavage in the Sprague-Dawley rat
Doin Jeon
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Fei Jia
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Hideto Jinno
2020 - Vol. 7 p.171-176
The aminoethyl group is a crucial structural moiety in metal-mediated oxidative DNA damage by catecholamines
Hong-Tao Jin
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Hui Ho Jeong
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
Huiho Jeong1
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
Huihoa Jeong
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Koji Jojima
2023 - Vol. 10 p.287-293
Development of an in silico consensus model for predicting the chemical reactivity to cysteine measured by the DPRA and its application to predict the skin sensitization potential of chemicals
2019 - Vol. 6 p.327-332
Development of a hepatotoxicity prediction model using in vitro assay data of key molecular events
Ran Jing
2019 - Vol. 6 p.207-215
Procyanidin protects HK-2 cells against cisplatin-induced injury through antioxidant action involving Nrf2/HO-1 signaling pathway
Rongrong Jiang
2017 - Vol. 4 p.195-200
Expression levels of 39 Cyp mRNAs in the mouse brain and neuroblastoma cell lines, C-1300N18 and NB2a – strong expression of Cyp1b1
Tomoko Jomura
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Wangdong Jin
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Yong-Ri Jin
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice

K

Acharya Bal Krishna
2016 - Vol. 3 p.9-12
Single dose oral toxicity study of Picrorhiza kurroa rhizome extract in Wistar rats
Akane Kanasaki
2021 - Vol. 8 p.23-31
The influence of long-term ingestion of D-allulose in hypercholesterolemia patients under statin therapy
2020 - Vol. 7 p.15-31
Safety and efficacy of a 48-week long-term ingestion of D-allulose in subjects with high LDL cholesterol levels
Akio Kawamura
2019 - Vol. 6 p.245-248
Comparison of cytotoxicity between fixed- and unfixed-combination ophthalmic solutions in vitro
Akio Kobayashi
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
Akira Kawashima
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
Ana Karen González Pérez
2021 - Vol. 8 p.81-88
Movento® 240SC (Spirotetramat) and Envidor® 240SC (Spirodiclofen) keto-enol insecticides induce DNA damage in Drosophila melanogaster ovaries
Asuka Kaizaki-Mitsumoto
2023 - Vol. 10 p.315-323
Flunitrazepam alters the toxicokinetics of chlorpromazine enhancing its toxicity
2023 - Vol. 10 p.179-187
Effect of blood collection tubes containing separation gels on the measurement of drug concentrations in clinical toxicology
2023 - Vol. 10 p.7-20
Paternal exposure to methylphenidate induces ADHD-like behavioral phenotypes and altered gene expressions in mouse offspring
2021 - Vol. 8 p.229-233
Time-dependent changes in serum concentrations of acyclovir and its metabolite, 9-carboxymethoxymethylguanine, in a patient with suspected acyclovir encephalopathy
Atsuhito Kushima
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Atsuko Katayanagi
2018 - Vol. 5 p.13-20
Increased hepatic triglyceride level induced by a glucokinase activator in mice
Atsuo Kishimoto
2014 - Vol. 1 p.1-6
Investigation of organ-specific assessment factors related to sub-acute and sub-chronic toxicity studies
Ayaka Kawai
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Ayako Kamimura
2017 - Vol. 4 p.219-227
A 4-week oral gavage toxicity study of L-citrulline in rats
Azusa Kawashima
2023 - Vol. 10 p.265-277
Differential expression of Cytochrome P450 1A2 in simple fatty liver and steatohepatitis
ByungHoon Kim
2019 - Vol. 6 p.45-56
Cytotoxic effects of parathion, paraoxon, and their methylated derivatives on a mouse neuroblastoma cell line NB41A3
Chika Kitaoka-Saito
2021 - Vol. 8 p.49-52
Acrylamide in dog food
Chikage Kawai
2020 - Vol. 7 p.201-206
Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
Daiki Kobayashi
2016 - Vol. 3 p.121-125
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes
Dhimas Agung Kurniawan
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Eisuke Kume
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023
Eri Kokubo
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
Eri Kurozumi
2015 - Vol. 2 p.217-222
Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes
Eriko Kohro-Ikeda
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Fujio Kayama
2018 - Vol. 5 p.87-91
Cadmium, arsenic and lead accumulation in rice grains produced in Senegal river valley
Fumiaki Kumagai
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
2017 - Vol. 4 p.109-119
Permeability of skin to silver nanoparticles after epidermal skin barrier disruption in rats
Futoshi Kuribayashi
2023 - Vol. 10 p.233-240
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
2022 - Vol. 9 p.151-157
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
2021 - Vol. 8 p.53-59
3’, 4’-Dihydroxyflavone enhances all-trans retinoic acid-induced superoxide-generating activity through up-regulating transcription of gp91-phox in human monoblastic U937 cells, as opposed to flavone and other hydroxyflavone derivatives
2020 - Vol. 7 p.201-206
Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
2019 - Vol. 6 p.319-325
Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells
2018 - Vol. 5 p.149-152
Positions and numbers of hydroxyl groups in hydroxychalcone derivatives are involved in cytotoxicity against human monoblastic U937 cells
2016 - Vol. 3 p.137-142
GCN5-deficiency remarkably enhances the sensitivity of B cells in response to 4-nitroquinoline 1-oxide
Gakushi Kito
2018 - Vol. 5 p.141-147
Anatomical and histological sex differences in the eye and its accessory tissues in Dutch belted rabbits
2018 - Vol. 5 p.83-85
Risk assessment of reproductive and developmental toxicity in eye-drop drugs: a consideration based on threshold of toxicological concern
Hajime Kojima
2020 - Vol. 7 p.9-14
Usefulness and limitations of mRNA measurement in HepaRG cells for evaluation of cytochrome P450 induction
Haruka Kunimi
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Haruko Koizumi
2023 - Vol. 10 p.209-219
Subchronic oral toxicity study of Monascus Color in beagle dogs
Hayato Kawakami
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
Hidehiko Kikuchi
2023 - Vol. 10 p.233-240
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
2022 - Vol. 9 p.151-157
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
2021 - Vol. 8 p.53-59
3’, 4’-Dihydroxyflavone enhances all-trans retinoic acid-induced superoxide-generating activity through up-regulating transcription of gp91-phox in human monoblastic U937 cells, as opposed to flavone and other hydroxyflavone derivatives
2020 - Vol. 7 p.201-206
Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
2019 - Vol. 6 p.319-325
Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells
2018 - Vol. 5 p.149-152
Positions and numbers of hydroxyl groups in hydroxychalcone derivatives are involved in cytotoxicity against human monoblastic U937 cells
2016 - Vol. 3 p.137-142
GCN5-deficiency remarkably enhances the sensitivity of B cells in response to 4-nitroquinoline 1-oxide
Hideshi Kaneko
2019 - Vol. 6 p.269-275
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats
Hideyuki Kuno
2017 - Vol. 4 p.9-14
Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs
Hina Kato
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
Hirokazu Kawagishi
2021 - Vol. 8 p.123-133
Safety evaluation of 2-aza-8-oxohypoxanthine by in vitro skin sensitization and human tests
2020 - Vol. 7 p.207-214
Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests
Hiroki Kashiwagi
2023 - Vol. 10 p.21-25
DNA damage mediated by 4,4'-methylenebis(2-chloroaniline) cannot be detected via the DNA damage marker γH2AX: A case study
Hiroki Kimoto
2022 - Vol. 9 p.71-83
Genotoxicity and subchronic toxicity of a kaempferol aglycone-rich product produced from horseradish leaves
Hiroki Kuwabara
2020 - Vol. 7 p.281-286
Influence of skin condition on the skin penetration of dextran 4000 and ovalbumin
Hiroshi Kawai
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
Hirotsugu Kato
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
Hiroyuki Kojima
2019 - Vol. 6 p.57-63
Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities
Hiroyuki Kuroda
2016 - Vol. 3 p.19-25
A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Hisaka Kurita
2016 - Vol. 3 p.257-280
DNA microarray analysis of fetal liver of C57BL/6J mice exposed to cadmium during gestation
Hisao Kitsuki
2018 - Vol. 5 p.117-122
Chlorella supplementation decreases methylmercury concentrations of hair and blood in healthy volunteers
Hitoshi Katou
2019 - Vol. 6 p.197-206
Multi-site study of an in vivo phototoxicity evaluation in Sprague-Dawley (SD) rats aimed at incorporating the phototoxicity assessments: effects of repeated administration and toxicokinetic blood collection on drug-induced phototoxicity
2019 - Vol. 6 p.171-179
Multi-site study of an in vivo phototoxicity evaluation in Sprague-Dawley rats: skin site and sex differences in sensitivity to drug-induced phototoxicity
Hyeon-Young Kim
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Iori Kodaira
2021 - Vol. 8 p.1-6
Comprehensive analysis of the alteration of plasma miRNA expression level in mice exposed to diesel exhaust
Jong-Choon Kim
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Jong-Mu Kim
2022 - Vol. 9 p.159-162
Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells
2021 - Vol. 8 p.157-160
Knockdown of deubiquitinating enzyme Usp34 confers resistance to methylmercury in HEK293 cells
Jong-Tar Kuo
2016 - Vol. 3 p.205-216
In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)
Jun Katagi
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Junichi Kikuchi
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
Junya Kobayashi
2022 - Vol. 9 p.47-59
Relationship between micronucleus formation and oxidative stress in human vascular endothelial cells under low dose rate irradiation
2021 - Vol. 8 p.249-260
Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture
Kana Kayasuga
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Kaori Kanemaru
2016 - Vol. 3 p.121-125
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes
Kaoru Kai
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
Kaoru Komoriya
2021 - Vol. 8 p.205-213
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity
Katsumi Kobayashi
2024 - Vol. 11 p.1-10
Repeated dose administration toxicity studies - Use of t-tests in multiplicity data analysis
2018 - Vol. 5 p.1-11
A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats
2017 - Vol. 4 p.247-259
Toxicity of repeated 28-day oral administration of acenaphthylene in rats
2017 - Vol. 4 p.207-218
Toxicity in repeated 28-day oral administration of N-phenyl-1-naphthylamine in rats
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
Kazuhiro Kobayashi
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
Kazuhiro Kuga
2019 - Vol. 6 p.197-206
Multi-site study of an in vivo phototoxicity evaluation in Sprague-Dawley (SD) rats aimed at incorporating the phototoxicity assessments: effects of repeated administration and toxicokinetic blood collection on drug-induced phototoxicity
2019 - Vol. 6 p.171-179
Multi-site study of an in vivo phototoxicity evaluation in Sprague-Dawley rats: skin site and sex differences in sensitivity to drug-induced phototoxicity
Kazuo Kuwata
2019 - Vol. 6 p.187-195
Oral toxicity study of an antiprion compound N,N’-[(cyclohexylmethylene)di-4,1-phenylene]bis[2-(1-pyrrolidinyl) acetamide] in rats and cynomolgus monkeys
Keiji Komemoto
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Ken-ichi Kiyomiya
2023 - Vol. 10 p.259-264
Titanium dioxide and silica nanoparticles inhibit the efflux of adriamycin in multi-drug resistant L1210/ADM cells
Kenichi Kobayashi
2018 - Vol. 5 p.153-159
In utero exposure to 2,2’,4,4’,5,5’-hexachlorobiphenyl accelerates the onset of eye opening in rat offspring
Kimika Kaneshima
2021 - Vol. 8 p.49-52
Acrylamide in dog food
Kimiyoshi Kitamura
2023 - Vol. 10 p.307-313
Derivation of permitted daily exposure value for trifluoroacetic acid as an impurity in pharmaceutical products
Kohei Kawabata
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
Kumiko Kusumoto
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Kuniyoshi Koyachi
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
2015 - Vol. 2 p.233-238
(–)-Xanthatin-mediated marked up-regulation of RhoB, a sensor for damaged DNA
Makiko Kuwagata
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
2023 - Vol. 10 p.69-82
A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
2023 - Vol. 10 p.59-68
A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats
2021 - Vol. 8 p.169-175
Development of an inhalation exposure system of a pressurized metered-dose inhaler (pMDI) formulation for small experimental animals
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
2017 - Vol. 4 p.109-119
Permeability of skin to silver nanoparticles after epidermal skin barrier disruption in rats
Maori Kono
2022 - Vol. 9 p.117-122
Leaf extracts from Camellia sinensis and Argania spinosa suppress oxidative stress and chemokine release in human 3-dimensional cultured epidermis exposed to PM2.5 collected with cyclonic separation
Masaaki Kurata
2019 - Vol. 6 p.245-248
Comparison of cytotoxicity between fixed- and unfixed-combination ophthalmic solutions in vitro
2018 - Vol. 5 p.141-147
Anatomical and histological sex differences in the eye and its accessory tissues in Dutch belted rabbits
2018 - Vol. 5 p.83-85
Risk assessment of reproductive and developmental toxicity in eye-drop drugs: a consideration based on threshold of toxicological concern
2017 - Vol. 4 p.105-107
A study for finding new phototoxicity descriptors related to potential energy
2017 - Vol. 4 p.95-99
Repeated-dose ocular instillation toxicity study: a survey of its study design on the basis of common technical documents in Japan
2016 - Vol. 3 p.217-232
Ocular instillation toxicity study: current status and points to consider on study design and evaluation
2015 - Vol. 2 p.147-153
In vitro comet assay in cultured human corneal epithelial cells
Masahiko Kurokawa
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Masaki Kakehi
2015 - Vol. 2 p.147-153
In vitro comet assay in cultured human corneal epithelial cells
Masaki Kaneniwa
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Masanobu Kanou
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
Masataka Kagawa
2014 - Vol. 1 p.39-47
Safety evaluation of morphological changes in corneal endothelial cells induced by K-115 in cynomolgus monkeys
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Masataka Kaneko
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Masayuki Kurimoto
2021 - Vol. 8 p.195-204
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals
Masuo Kondoh
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Michihiro Kamijima
2017 - Vol. 4 p.201-205
Organophosphorus insecticide dichlorvos inhibits fatty acid amide hydrolase in the male reproductive organs of rats
Mihoko Koyanagi
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Min-Seok Kim
2021 - Vol. 8 p.157-160
Knockdown of deubiquitinating enzyme Usp34 confers resistance to methylmercury in HEK293 cells
2018 - Vol. 5 p.71-73
Putrescine selectively alleviates methylmercury toxicity in C17.2 mouse neural stem cells
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
2017 - Vol. 4 p.41-43
Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells
2015 - Vol. 2 p.245-247
Knockdown of Acyl-CoA thioesterase 9 gene expression by siRNA confers resistance to arsenite in HEK293 cells
2015 - Vol. 2 p.239-243
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
Min-Soek Kim
2017 - Vol. 4 p.37-39
Identification of transcription factors activated by methylmercury in mouse brain
Min-Sung Kang
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Miyoko Kubo-Irie
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Motoharu Kakiki
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Motoi Kuratani
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Munekazu Komada
2015 - Vol. 2 p.79-82
Motor activities of newborns prenatally exposed to low-dose bisphenol A in diverse mouse strains
2015 - Vol. 2 p.37-39
Effects of prenatal exposure to low doses of diethylstilbestrol on motor activity in newborn mice
Nakao Kojima
2020 - Vol. 7 p.171-176
The aminoethyl group is a crucial structural moiety in metal-mediated oxidative DNA damage by catecholamines
2014 - Vol. 1 p.73-79
Effects of organic and inorganic mercury(II) on gene expression via DNA conformational changes
Nao Kagawa
2015 - Vol. 2 p.79-82
Motor activities of newborns prenatally exposed to low-dose bisphenol A in diverse mouse strains
2015 - Vol. 2 p.37-39
Effects of prenatal exposure to low doses of diethylstilbestrol on motor activity in newborn mice
Nao Kikugawa
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Naohiro Kidoguchi
2020 - Vol. 7 p.33-40
Triphenyltin inhibits GA-binding protein α nuclear translocation
Naohito Kawasaki
2021 - Vol. 8 p.147-155
Relationship between renal dysfunction and change in serum electrolyte levels in patients administered with liposomal amphotericin B
Naoki Kanematsu
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Naoki Kobayashi
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
Naomi Kudo
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Naoyuki Kurokawa
2015 - Vol. 2 p.67-78
Effect of prenatal methylmercury exposure on neurobehavioral development in male mice: comparison between methylmercury in fish and methylmercury chloride added to diets
Naruo Katsutani
2021 - Vol. 8 p.195-204
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals
Nobuyuki Kanemaki
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Norikazu Komoriya
2019 - Vol. 6 p.249-252
Localization of the trichloroethylene-related compound S-(1, 2-dichlorovinyl)-L-cysteine in mouse cartilage
Noriko Kemuriyama
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Noriko Kuroiwa
2021 - Vol. 8 p.1-6
Comprehensive analysis of the alteration of plasma miRNA expression level in mice exposed to diesel exhaust
Norio Kamemura
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Noriyuki Koyama
2022 - Vol. 9 p.71-83
Genotoxicity and subchronic toxicity of a kaempferol aglycone-rich product produced from horseradish leaves
Reiko Kato
2021 - Vol. 8 p.205-213
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity
Ryo Kawahara
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Sadahiro Kawazoe
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
Saho Kobayashi
2023 - Vol. 10 p.21-25
DNA damage mediated by 4,4'-methylenebis(2-chloroaniline) cannot be detected via the DNA damage marker γH2AX: A case study
Saori Kikutsugi
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Satomi Kawaguchi
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Satomi Kikuchi
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Satomi Komatsu
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Satoshi Kitajima
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
2023 - Vol. 10 p.69-82
A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
2023 - Vol. 10 p.59-68
A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats
2022 - Vol. 9 p.17-21
A novel high-purity carbon-nanotube yarn electrode used to obtain biopotential measurements in small animals: flexible, wearable, less invasive, and gel-free operation
2021 - Vol. 8 p.169-175
Development of an inhalation exposure system of a pressurized metered-dose inhaler (pMDI) formulation for small experimental animals
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
2018 - Vol. 5 p.167-170
Derivation of acceptable daily exposure value for alanine, N,N-bis(carboxymethyl)-, trisodium salt
Satoshi Kitaoka
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Satoshi Kondo
2023 - Vol. 10 p.169-178
Toxicological effects of repeated subcutaneous administration of corn oil for 4 weeks in rats
Satoshi Kotoura
2019 - Vol. 6 p.367-382
Safety evaluation of chicken breast meat extract in chromosomal aberration study, reverse mutation test, and 90-day repeated dose study in rats
Satoshi Koyama
2020 - Vol. 7 p.9-14
Usefulness and limitations of mRNA measurement in HepaRG cells for evaluation of cytochrome P450 induction
Seiichiro Kurashige
2022 - Vol. 9 p.103-110
Fecal microRNA223 as an indicator of recovery in chronic DSS colitis model in rats
2021 - Vol. 8 p.177-182
Expression of miRNAs in the colon, rectum, plasma, and feces in rats with dextran sulfate sodium
Seiji Kanda
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Shibo Kong
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Shigeyuki Kitamura
2019 - Vol. 6 p.57-63
Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities
2018 - Vol. 5 p.185-193
Study of metabolic activation of the UV-filter octyl methoxycinnamate for endocrine-disrupting activity
2016 - Vol. 3 p.177-183
Estimation of occupational exposure to drugs during tablet crushing
Shinnosuke Kondo
2019 - Vol. 6 p.235-243
High-dose β-carotene exacerbates high-fat/high-sucrose diet-inducible fibrosis in the liver of Mongolian gerbils
Shino Kumabe
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Shinsuke Katoh
2021 - Vol. 8 p.249-260
Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture
Shinya Kaneda
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Shohei Kaneko
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Shugo Kazama
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Shusuke Kuge
2017 - Vol. 4 p.41-43
Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells
2016 - Vol. 3 p.75-77
Overexpression of palmitoyl transferase HIP14 confers resistance to methylmercury in SH-SY5Y human neuroblastoma cells
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
2015 - Vol. 2 p.245-247
Knockdown of Acyl-CoA thioesterase 9 gene expression by siRNA confers resistance to arsenite in HEK293 cells
2015 - Vol. 2 p.223-226
Methylmercury induces release of a cytotoxic factor from HEK293 cells into medium
2014 - Vol. 1 p.113-114
Identification of growth-dependent genes involved in paraquat toxicity in Saccharomyces cerevisiae
2014 - Vol. 1 p.109-111
Overexpression of RPN8, SKP1, MIA40 or MES1 increases resistance to cadmium in Saccharomyces cerevisiae
2014 - Vol. 1 p.95-99
A screening method for growth-dependent genes involved in the cytotoxicity of chemicals in Saccharomyces cerevisiae
Shuuhei Kubo
2023 - Vol. 10 p.209-219
Subchronic oral toxicity study of Monascus Color in beagle dogs
Soonih Kim
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Sung-Hwan Kim
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Susumu Kono
2021 - Vol. 8 p.189-193
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity
Taiki Kobayashi
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
Takahiro Kimura
2020 - Vol. 7 p.133-139
Sex differences in the effects of high-fat diet on mouse sciatic nerves
2020 - Vol. 7 p.115-121
Effects of estrogen on fatty-acid-induced cytotoxicity in mouse Neuro-2a neural cells
Takahiro Kyoya
2020 - Vol. 7 p.133-139
Sex differences in the effects of high-fat diet on mouse sciatic nerves
2020 - Vol. 7 p.115-121
Effects of estrogen on fatty-acid-induced cytotoxicity in mouse Neuro-2a neural cells
2018 - Vol. 5 p.63-69
Assessment of bladder DNA damage due to 2-acetylaminofluorene, diuron, and terephthalic acid by the rat comet assay
2018 - Vol. 5 p.57-62
Scanning electron microscopic analysis of the bladder epithelium in terephthalic acid administered rats: a case in acute toxicity study
Takashi Kitaguchi
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
Takayuki Kumamoto
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
Takeshi Kumagai
2021 - Vol. 8 p.157-160
Knockdown of deubiquitinating enzyme Usp34 confers resistance to methylmercury in HEK293 cells
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Takeyoshi Kamamoto
2015 - Vol. 2 p.155-159
Effects of rofecoxib on lipid oxidation in plasma and aortas of rats
Teppei Koreeda
2023 - Vol. 10 p.259-264
Titanium dioxide and silica nanoparticles inhibit the efflux of adriamycin in multi-drug resistant L1210/ADM cells
Terutaka Kodama
2022 - Vol. 9 p.103-110
Fecal microRNA223 as an indicator of recovery in chronic DSS colitis model in rats
2021 - Vol. 8 p.177-182
Expression of miRNAs in the colon, rectum, plasma, and feces in rats with dextran sulfate sodium
2014 - Vol. 1 p.29-38
28-Day dietary toxicity study of L-phenylalanine in rats
Tomohiro Kikuchi
2015 - Vol. 2 p.171-175
Health survey of workers in a 2,4,6-trinitrotoluene explosives factory in Fuxin, China
Tomoki Kimura
2022 - Vol. 9 p.25-30
Erratum: Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2017 - Vol. 4 p.121-126
Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
Tomoki Kinoshita
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Tomoko Kawamura
2021 - Vol. 8 p.195-204
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals
2019 - Vol. 6 p.125-136
Validation of the statistical parameters and model selection criteria of the benchmark dose methods for the evaluation of various endpoints in repeated-dose toxicity studies
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
Toshihiro Kanno
2018 - Vol. 5 p.117-122
Chlorella supplementation decreases methylmercury concentrations of hair and blood in healthy volunteers
Toshihiro Kawamoto
2016 - Vol. 3 p.63-65
Transcription factor activation in rat primary astrocytes exposed to methylmercury
Toshihiro Kobayashi
2020 - Vol. 7 p.167-170
Bacteriological evaluation of feasibility of food poisoning from long-term stored “pack-cooked” meals
Toshikazu Kamiya
2019 - Vol. 6 p.65-74
Twenty-eight-day oral toxicity study of L-hydroxyproline in rats with 14-day post-treatment observation period
Toshiko Kinomoto
2016 - Vol. 3 p.19-25
A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Toshiyuki Kaji
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
2020 - Vol. 7 p.77-83
Arsenite inhibits gene expression of perlecan, syndecan-1, -2, -3 and biglycan in cultured vascular endothelial cells
2018 - Vol. 5 p.181-184
A zinc complex that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
Tsukasa Kikuno
2023 - Vol. 10 p.307-313
Derivation of permitted daily exposure value for trifluoroacetic acid as an impurity in pharmaceutical products
Tsutomu Kimura
2019 - Vol. 6 p.187-195
Oral toxicity study of an antiprion compound N,N’-[(cyclohexylmethylene)di-4,1-phenylene]bis[2-(1-pyrrolidinyl) acetamide] in rats and cynomolgus monkeys
Tsuyoshi Kawakami
2021 - Vol. 8 p.205-213
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity
Yaichiro Kotake
2020 - Vol. 7 p.33-40
Triphenyltin inhibits GA-binding protein α nuclear translocation
Yasuhiro Kinpara
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Yoichi Kawashima
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Yoko Kawada
2019 - Vol. 6 p.65-74
Twenty-eight-day oral toxicity study of L-hydroxyproline in rats with 14-day post-treatment observation period
Yoshiki Kaneko
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Yoshiko Kobayashi
2021 - Vol. 8 p.249-260
Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture
Yoshinobu Kawahara
2016 - Vol. 3 p.39-46
Toxicogenomic prediction with graph-based structured regularization on transcription factor network
2015 - Vol. 2 p.161-170
Toxicogenomic prediction with group sparse regularization based on transcription factor network information
Yoshito Kumagai
2022 - Vol. 9 p.1-5
Glyceraldehyde 3-phosphate dehydrogenase converts methylmercury to its sulfur adduct with lowered toxicity through sulfane sulfur atoms on Cys247
2020 - Vol. 7 p.161-166
Combined exposure to environmental electrophiles enhances cytotoxicity and consumption of persulfide
2015 - Vol. 2 p.171-175
Health survey of workers in a 2,4,6-trinitrotoluene explosives factory in Fuxin, China
Yuasa Koki
2019 - Vol. 6 p.367-382
Safety evaluation of chicken breast meat extract in chromosomal aberration study, reverse mutation test, and 90-day repeated dose study in rats
Yuka Kohda
2023 - Vol. 10 p.83-90
Effects of continuous thiamine intake on onset and progression of type 2 diabetes in leptin-receptor deficient mice
2021 - Vol. 8 p.235-241
Focus on orexin-A in obese diabetes rats: upregulation of orexin-A receptor in the diabetic brain
2020 - Vol. 7 p.291-299
Age-related hepatic glucose-dependent insulinotropic polypeptide expression is modified by ongoing thiamine supplementation in obese diabetic rats
2019 - Vol. 6 p.383-390
Obesity-related hypertension and enhanced plasma orexin-A level are attenuated by the consumption of thiamine water in diabetic rats under cerebral oxidative stress conditions
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
2017 - Vol. 4 p.279-284
Hepatic glucose-dependent insulinotropic polypeptide expression is modified by supplementing high-dose thiamine in obese diabetic rats
2016 - Vol. 3 p.291-296
Streptozotocin-induced diabetic state triggers glucose-dependent insulinotropic polypeptide (GIP) expression in the rat liver
2015 - Vol. 2 p.55-60
Metabolic fate of excessive glucose in fibroblast cells in a diabetic setting
Yukari Kobayashi
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
Yukie Kuroda
2020 - Vol. 7 p.249-252
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
Yukiko Kobayashi
2023 - Vol. 10 p.143-156
Safety studies of LAURESH® a standardized Laurus nobilis leaf extract
Yukio Kato
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Yuko Kato-Yoshinaga
2021 - Vol. 8 p.49-52
Acrylamide in dog food
Yumi Kawazoe
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Yuta Kamiya
2014 - Vol. 1 p.101-108
Sex-dependent difference in the hepatic and pulmonary toxicological effects in mice administrated 7-chlorinated benz[a]anthracene
Yuya Kurumi
2015 - Vol. 2 p.217-222
Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes

L

Bo Li
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
Chao Li
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Chin-Chung Lin
2016 - Vol. 3 p.205-216
In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)
Chunqi Li
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Hong-Soo Lee
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Hongcui Liu
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Hongwen Li
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Hui Li
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
J. Timothy Lightfoot
2020 - Vol. 7 p.189-199
Postnatal wheel running mitigates endocrine disruption of mammary gland development in mice
Jian-Yu Lin
2019 - Vol. 6 p.81-106
Genotoxicity and subchronic toxicity studies of Taiwanofungus camphoratus extract
Jin Li
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Jin-Yong Lee
2023 - Vol. 10 p.133-136
Effect of cadmium on expression of BIRC family genes in HeLa cells
2022 - Vol. 9 p.159-162
Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells
2021 - Vol. 8 p.157-160
Knockdown of deubiquitinating enzyme Usp34 confers resistance to methylmercury in HEK293 cells
2018 - Vol. 5 p.93-97
Effect of heat shock protein gene expression on cadmium toxicity in human proximal tubular cells
2018 - Vol. 5 p.71-73
Putrescine selectively alleviates methylmercury toxicity in C17.2 mouse neural stem cells
2017 - Vol. 4 p.275-278
Effect of chronic cadmium exposure on the gene expression of Birc family in the mouse kidney and liver
2017 - Vol. 4 p.269-273
Effect of metallothionein on ethanol-induced hepatotoxicity in mice
2017 - Vol. 4 p.37-39
Identification of transcription factors activated by methylmercury in mouse brain
2016 - Vol. 3 p.285-289
Sensitivity of MT-III null mice upon chronic exposure to cadmium
2016 - Vol. 3 p.281-284
Cadmium-induced protein ubiquitination in UBA80 knockdown HK-2 cells
2016 - Vol. 3 p.257-280
DNA microarray analysis of fetal liver of C57BL/6J mice exposed to cadmium during gestation
2016 - Vol. 3 p.185-193
Neurobehavioral toxicity related to the exposure of weaning mice to low-level mercury vapor and methylmercury and influence of aging
2015 - Vol. 2 p.259-262
The enhancement effect of HIST1H4C knockdown on cadmium toxicity in human proximal tubular cells
2014 - Vol. 1 p.165-167
The involvement of GPRC5B in cadmium toxicity in HK-2 cells
2014 - Vol. 1 p.131-133
Effects of cadmium on the gene expression of SLC39A1 coding for ZIP1 protein
Jinfeng Liang
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Jinqiang Liang
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Jiunn-Wang Liao
2016 - Vol. 3 p.205-216
In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)
Kwang-Hyun Lim
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Kyuhong Lee
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Lin Lin
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Moo-Yeol Lee
2016 - Vol. 3 p.285-289
Sensitivity of MT-III null mice upon chronic exposure to cadmium
2014 - Vol. 1 p.165-167
The involvement of GPRC5B in cadmium toxicity in HK-2 cells
2014 - Vol. 1 p.131-133
Effects of cadmium on the gene expression of SLC39A1 coding for ZIP1 protein
Sangho Lee
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Song Li
2015 - Vol. 2 p.171-175
Health survey of workers in a 2,4,6-trinitrotoluene explosives factory in Fuxin, China
Tian-Tian Liu
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Tongqiang Liu
2019 - Vol. 6 p.207-215
Procyanidin protects HK-2 cells against cisplatin-induced injury through antioxidant action involving Nrf2/HO-1 signaling pathway
Wei Li
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Woo-Jong Lee
2018 - Vol. 5 p.33-48
Subacute toxicity evaluation of KMRC011, a Toll-like receptor-5 agonist administered by intramuscular injection to rats
Xu-Wen Li
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
Ya-Hao Ling
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Ye Li
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Yong-Jin Lee
2019 - Vol. 6 p.45-56
Cytotoxic effects of parathion, paraoxon, and their methylated derivatives on a mouse neuroblastoma cell line NB41A3
Yu-Hsing Lin
2016 - Vol. 3 p.205-216
In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)
Zhifei Liu
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats

M

Aki Miyauchi
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Akie Maekita
2017 - Vol. 4 p.279-284
Hepatic glucose-dependent insulinotropic polypeptide expression is modified by supplementing high-dose thiamine in obese diabetic rats
Akihiko Matsumoto
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Akihiro Michihara
2023 - Vol. 10 p.325-333
Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Akira Moriguchi
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
Akitaka Matsuda
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Alice Maria Costa Martins
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
Ashley Meeks
2019 - Vol. 6 p.45-56
Cytotoxic effects of parathion, paraoxon, and their methylated derivatives on a mouse neuroblastoma cell line NB41A3
Atsufumi Manabe
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Atsuko Miyajima
2021 - Vol. 8 p.205-213
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity
2020 - Vol. 7 p.249-252
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Atsushi Matsuzawa
2022 - Vol. 9 p.159-162
Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells
Atsushi Mitsumoto
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Atsushi Miyajima
2015 - Vol. 2 p.155-159
Effects of rofecoxib on lipid oxidation in plasma and aortas of rats
Ayako Mimata
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Chiaki Minamigawa
2016 - Vol. 3 p.291-296
Streptozotocin-induced diabetic state triggers glucose-dependent insulinotropic polypeptide (GIP) expression in the rat liver
Chika Manabe
2023 - Vol. 10 p.113-123
A trial to predict skin irritancy of cosmetic products using cytotoxicity tests
Chikako Maeda
2017 - Vol. 4 p.195-200
Expression levels of 39 Cyp mRNAs in the mouse brain and neuroblastoma cell lines, C-1300N18 and NB2a – strong expression of Cyp1b1
Chizuru Matsuura
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
Daisaku Miura
2023 - Vol. 10 p.259-264
Titanium dioxide and silica nanoparticles inhibit the efflux of adriamycin in multi-drug resistant L1210/ADM cells
Daishiro Miura
2019 - Vol. 6 p.269-275
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats
Daisuke Miyazawa
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Dalgimar Beserra de Menezes
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Eiko Matsumoto
2020 - Vol. 7 p.9-14
Usefulness and limitations of mRNA measurement in HepaRG cells for evaluation of cytochrome P450 induction
Emi Matsumoto
2019 - Vol. 6 p.269-275
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats
Fernanda Martins
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Fukutaro Mizuhashi
2016 - Vol. 3 p.1-8
Physiological conditions in iPRECIO® -implanted rats
Hajime Miura
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Harishkumar Madhyastha
2023 - Vol. 10 p.233-240
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
2022 - Vol. 9 p.151-157
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
2021 - Vol. 8 p.53-59
3’, 4’-Dihydroxyflavone enhances all-trans retinoic acid-induced superoxide-generating activity through up-regulating transcription of gp91-phox in human monoblastic U937 cells, as opposed to flavone and other hydroxyflavone derivatives
2020 - Vol. 7 p.201-206
Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
2019 - Vol. 6 p.319-325
Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells
2018 - Vol. 5 p.149-152
Positions and numbers of hydroxyl groups in hydroxychalcone derivatives are involved in cytotoxicity against human monoblastic U937 cells
Helena Serra Azul Monteiro
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Hemanth Kumar Manikyam
2016 - Vol. 3 p.9-12
Single dose oral toxicity study of Picrorhiza kurroa rhizome extract in Wistar rats
Hideo Mohri
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Hikaru Mitori
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
Hiroka Matsuzaki
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
Hiroki Maruyama
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
Hiroko Miyoshi
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
2015 - Vol. 2 p.233-238
(–)-Xanthatin-mediated marked up-regulation of RhoB, a sensor for damaged DNA
Hiroshi Matsuoka
2023 - Vol. 10 p.325-333
Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Hiroto Murase
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
Hiroyuki Moriguchi
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Hisanori Minami
2019 - Vol. 6 p.319-325
Sulforaphane displays the growth inhibition, cytotoxicity and enhancement of retinoic acid-induced superoxide-generating activity in human monoblastic U937 cells
Hitomi Mimuro
2023 - Vol. 10 p.233-240
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
2022 - Vol. 9 p.151-157
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
2016 - Vol. 3 p.137-142
GCN5-deficiency remarkably enhances the sensitivity of B cells in response to 4-nitroquinoline 1-oxide
Hitoshi Matsumura
2019 - Vol. 6 p.383-390
Obesity-related hypertension and enhanced plasma orexin-A level are attenuated by the consumption of thiamine water in diabetic rats under cerebral oxidative stress conditions
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
2017 - Vol. 4 p.279-284
Hepatic glucose-dependent insulinotropic polypeptide expression is modified by supplementing high-dose thiamine in obese diabetic rats
2016 - Vol. 3 p.291-296
Streptozotocin-induced diabetic state triggers glucose-dependent insulinotropic polypeptide (GIP) expression in the rat liver
2015 - Vol. 2 p.55-60
Metabolic fate of excessive glucose in fibroblast cells in a diabetic setting
Hitoshi Mitsuzumi
2022 - Vol. 9 p.23-23
Erratum: Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
2019 - Vol. 6 p.341-357
Safety assessment of isomaltodextrin-producing enzymes from Paenibacillus alginolyticus
2017 - Vol. 4 p.57-75
Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
Ikuko Matsuno
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
Ikuo Matsuura
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Isao Maruyama
2018 - Vol. 5 p.117-122
Chlorella supplementation decreases methylmercury concentrations of hair and blood in healthy volunteers
Izumi Matsumoto
2024 - Vol. 11 p.57-67
Effects of food restriction for 3 or 7 days on toxicity-related parameters in rats
Izuru Miyawaki
2024 - Vol. 11 p.57-67
Effects of food restriction for 3 or 7 days on toxicity-related parameters in rats
Kaho Miyahara
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Kanta Matsui
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
Katsuhiro Miyajima
2021 - Vol. 8 p.221-228
Influence of trans-fatty acids on non-alcoholic steatohepatitis with hepatic fibrosis induced by a choline-deficient, methionine-lowered, L-amino acid-defined diet in male Harlan Sprague Dawley rats
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Katsushi Miyake
2016 - Vol. 3 p.177-183
Estimation of occupational exposure to drugs during tablet crushing
Katsuyoshi Mitsunaga
2020 - Vol. 7 p.249-252
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Kazuhiko Mori
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Kazuki Matsuda
2022 - Vol. 9 p.203-209
An in vitro microfluidic culture device for peripheral neurotoxicity prediction at low concentrations based on deep learning
Kazuki Mochizuki
2019 - Vol. 6 p.235-243
High-dose β-carotene exacerbates high-fat/high-sucrose diet-inducible fibrosis in the liver of Mongolian gerbils
2019 - Vol. 6 p.15-23
Supplementation with lower doses of EGCg reduces liver injury markers of type 2 diabetic rats
Kenichi Masumura
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
Kenji Matsumoto
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
2015 - Vol. 2 p.233-238
(–)-Xanthatin-mediated marked up-regulation of RhoB, a sensor for damaged DNA
Kenta Mizoi
2020 - Vol. 7 p.9-14
Usefulness and limitations of mRNA measurement in HepaRG cells for evaluation of cytochrome P450 induction
Kevin G. McGarry
2016 - Vol. 3 p.195-204
Acute toxicity of phorate oxon by oral gavage in the Sprague-Dawley rat
Koichi Morita
2022 - Vol. 9 p.17-21
A novel high-purity carbon-nanotube yarn electrode used to obtain biopotential measurements in small animals: flexible, wearable, less invasive, and gel-free operation
Koji Morishita
2019 - Vol. 6 p.65-74
Twenty-eight-day oral toxicity study of L-hydroxyproline in rats with 14-day post-treatment observation period
2017 - Vol. 4 p.219-227
A 4-week oral gavage toxicity study of L-citrulline in rats
2014 - Vol. 1 p.63-72
A 4-week oral toxicity study of L-alanine in rats with a recovery period of 2 weeks
2014 - Vol. 1 p.49-62
A 13-week feeding toxicity study of L-threonine in rats with a recovery period of 5 weeks
Koji Murao
2021 - Vol. 8 p.23-31
The influence of long-term ingestion of D-allulose in hypercholesterolemia patients under statin therapy
2020 - Vol. 7 p.15-31
Safety and efficacy of a 48-week long-term ingestion of D-allulose in subjects with high LDL cholesterol levels
Kosho Makino
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Kyoko Miwa
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Makiko Motoi
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Makiko Motoi-Ohtsuji
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Manami Matsumoto
2022 - Vol. 9 p.85-93
Occupational exposure of pharmacists to drugs during tablet crushing and its countermeasures
Marika Matsumoto
2021 - Vol. 8 p.221-228
Influence of trans-fatty acids on non-alcoholic steatohepatitis with hepatic fibrosis induced by a choline-deficient, methionine-lowered, L-amino acid-defined diet in male Harlan Sprague Dawley rats
Mariko Matsumoto
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
2019 - Vol. 6 p.125-136
Validation of the statistical parameters and model selection criteria of the benchmark dose methods for the evaluation of various endpoints in repeated-dose toxicity studies
2018 - Vol. 5 p.1-11
A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats
2017 - Vol. 4 p.247-259
Toxicity of repeated 28-day oral administration of acenaphthylene in rats
2017 - Vol. 4 p.207-218
Toxicity in repeated 28-day oral administration of N-phenyl-1-naphthylamine in rats
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
2015 - Vol. 2 p.177-190
Repeated dose and reproductive/developmental toxicity of long-chain perfluoroalkyl carboxylic acids in rats: perfluorohexadecanoic acid and perfluorotetradecanoic acid
Mariko Morii
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Masaaki Miyata
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Masahiko Morita
2017 - Vol. 4 p.219-227
A 4-week oral gavage toxicity study of L-citrulline in rats
Masahiro Mochizuki
2014 - Vol. 1 p.63-72
A 4-week oral toxicity study of L-alanine in rats with a recovery period of 2 weeks
Masaki Murakami
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
Masanori Miura
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Masatsugu Miyara
2020 - Vol. 7 p.33-40
Triphenyltin inhibits GA-binding protein α nuclear translocation
Masaya Matsumoto
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
Masayuki Mishima
2023 - Vol. 10 p.307-313
Derivation of permitted daily exposure value for trifluoroacetic acid as an impurity in pharmaceutical products
2023 - Vol. 10 p.301-306
Derivation of the permitted daily exposure value for p-tert-butylphenol as an impurity in pharmaceutical products
2023 - Vol. 10 p.295-300
Derivation of permitted daily exposure value for 1,8-diazabicyclo[5.4.0]undec-7-ene in pharmaceutical products
2018 - Vol. 5 p.167-170
Derivation of acceptable daily exposure value for alanine, N,N-bis(carboxymethyl)-, trisodium salt
Mihoko Mori
2017 - Vol. 4 p.261-268
Suppressive effect of Sasa veitchii extract on obesity induced by a high-fat diet through modulation of adipose differentiation in mice
Mikako Matsuo
2016 - Vol. 3 p.291-296
Streptozotocin-induced diabetic state triggers glucose-dependent insulinotropic polypeptide (GIP) expression in the rat liver
Minori Mezaki
2023 - Vol. 10 p.113-123
A trial to predict skin irritancy of cosmetic products using cytotoxicity tests
Mio Matsumura
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
Mitsuaki Masuyama
2019 - Vol. 6 p.269-275
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys
Mizuki Mizobuchi
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Motohiko Morihara
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Muneyuki Miyagawa
2018 - Vol. 5 p.153-159
In utero exposure to 2,2’,4,4’,5,5’-hexachlorobiphenyl accelerates the onset of eye opening in rat offspring
Naoki Matsuda
2022 - Vol. 9 p.203-209
An in vitro microfluidic culture device for peripheral neurotoxicity prediction at low concentrations based on deep learning
Naoko Mori
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Naomi Matsutani
2022 - Vol. 9 p.103-110
Fecal microRNA223 as an indicator of recovery in chronic DSS colitis model in rats
2021 - Vol. 8 p.177-182
Expression of miRNAs in the colon, rectum, plasma, and feces in rats with dextran sulfate sodium
Nathan Mise
2018 - Vol. 5 p.87-91
Cadmium, arsenic and lead accumulation in rice grains produced in Senegal river valley
Nobuhiko Miura
2019 - Vol. 6 p.113-116
Impairment of fertilization efficiency in mice following nano-sized titanium exposure
2019 - Vol. 6 p.25-29
Protective effect of the Kampo formula “Juzen-taiho-to” on isoniazid- and rifampicin-induced hepatotoxicity in mice
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
2017 - Vol. 4 p.37-39
Identification of transcription factors activated by methylmercury in mouse brain
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
2016 - Vol. 3 p.233-236
Hepatoprotective effect of kampo formula “Juzen-taiho-to” on bromobenzene-induced toxicity in mice
2016 - Vol. 3 p.75-77
Overexpression of palmitoyl transferase HIP14 confers resistance to methylmercury in SH-SY5Y human neuroblastoma cells
2015 - Vol. 2 p.239-243
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
2014 - Vol. 1 p.161-164
CDC23 knockdown reinforces methylmercury sensitivity in HEK293 cells
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Norihito Matsumoto
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Norikazu Miyoshi
2017 - Vol. 4 p.173-178
Cytometric analysis on cytotoxicity of 4,4′-methylenediphenyl diisocyanate, a chemical allergen, in rat thymocytes
Osamu Morita
2016 - Vol. 3 p.251-256
Validation of retrospective evaluation method for false genotoxic chemicals with strong cytotoxicity: re-evaluation using in vitro micronucleus test
Qingmei Meng
2022 - Vol. 9 p.47-59
Relationship between micronucleus formation and oxidative stress in human vascular endothelial cells under low dose rate irradiation
Ramon Róseo Paula Pessoa Bezerra de Menezes
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
Ramu Mizunoe
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Rena Makino
2014 - Vol. 1 p.73-79
Effects of organic and inorganic mercury(II) on gene expression via DNA conformational changes
Ricardo P. Moreira
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Risa Matsui
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
Robert R. Maronpot
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Ryoji Matsushima
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Saki Matsuo
2016 - Vol. 3 p.55-61
HU-210, a synthetic analog of Δ9-THC, is not a modifier of estrogen signaling in MCF-7 human breast cancer cells
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
Saki Mikami
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
Satoru Miyazaki
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Sayaka Murata
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
Seiichiro Maeda
2022 - Vol. 9 p.167-172
Induction of CYP3A4 mRNA by cooked food-derived carcinogenic heterocyclic aromatic amines in human HPL-A3 cells
Shingo Miyata
2014 - Vol. 1 p.169-172
Estimation of endoplasmic reticulum stress-inducing ability of nobiletin, a citrus polymethoxyflavonoid, in SK-N-SH human neuroblastoma cells
Shizuko Maeda
2016 - Vol. 3 p.177-183
Estimation of occupational exposure to drugs during tablet crushing
Shotaro Matsuzawa
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
Shuichi Masuda
2022 - Vol. 9 p.173-178
Assessment of genotoxicity of 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) in zebrafish (Danio rerio) using the comet assay and micronucleus test
2019 - Vol. 6 p.9-14
Investigation of DNA damage of glycidol and glycidol fatty acid esters using Fpg-modified comet assay
2018 - Vol. 5 p.63-69
Assessment of bladder DNA damage due to 2-acetylaminofluorene, diuron, and terephthalic acid by the rat comet assay
Shuji Matsumoto
2020 - Vol. 7 p.141-152
Maltosyltrehalose Syrup: Bacterial reverse mutation test, and 90-day feeding and 90-day repeated oral dose toxicity studies in rats
2019 - Vol. 6 p.299-317
Glucosyl hesperidin: safety studies
Souichi Murakami
2015 - Vol. 2 p.223-226
Methylmercury induces release of a cytotoxic factor from HEK293 cells into medium
Tadashi Miwa
2014 - Vol. 1 p.29-38
28-Day dietary toxicity study of L-phenylalanine in rats
Taeko Maruyama
2021 - Vol. 8 p.195-204
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals
Taisei Mizota
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
Takahiro Matsuda
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
Takayasu Moroki
2023 - Vol. 10 p.169-178
Toxicological effects of repeated subcutaneous administration of corn oil for 4 weeks in rats
Takeshi Matsubara
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Taku Masuyama
2020 - Vol. 7 p.153-160
Usefulness of HepaRG cells in the mitochondrial function assay for the estimation of potential risk of idiosyncratic drug-induced liver injury
2017 - Vol. 4 p.9-14
Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs
Takunori Matsumoto
2021 - Vol. 8 p.123-133
Safety evaluation of 2-aza-8-oxohypoxanthine by in vitro skin sensitization and human tests
Takuya Matsui
2018 - Vol. 5 p.21-32
Comparison of stabilities of nitrenium ions and in vitro and in vivo genotoxic potential, between four aniline derivatives
Tatsuhiro Matsuo
2019 - Vol. 6 p.217-224
Recovery of increased weights of the liver and kidneys by cessation of D-allulose feeding in Wistar rats
Toby M. Michelena
2023 - Vol. 10 p.279-285
K16ApoE interrupts cerebral blood flow and induces blood cell aggregation in mice
2023 - Vol. 10 p.125-131
K16ApoE inhibits the activity of acetylcholinesterase but is not the primary toxicological mechanism in mice
Toby M. Michelena
2018 - Vol. 5 p.123-126
The impact on the activity of acetylcholinesterase of a polylysine-ApoE peptide carrier targeting the blood brain barrier
Tohru Maeda
2019 - Vol. 6 p.25-29
Protective effect of the Kampo formula “Juzen-taiho-to” on isoniazid- and rifampicin-induced hepatotoxicity in mice
Tomoko Muto
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023
Toru Maruyama
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Toshiyasu Mikuma
2023 - Vol. 10 p.265-277
Differential expression of Cytochrome P450 1A2 in simple fatty liver and steatohepatitis
Tsuyoshi Murahashi
2022 - Vol. 9 p.187-196
Pharmaceutical concentrations and antimicrobial activity using hypersusceptible Escherichia coli lacking TolC component of multidrug efflux system in the Ayase River in Japan
2022 - Vol. 9 p.85-93
Occupational exposure of pharmacists to drugs during tablet crushing and its countermeasures
Wen-Bo Mu
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Yasuhiro Masuda
2019 - Vol. 6 p.107-112
Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction
Yasumasa Murata
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
Yasunori Masubuchi
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Yohei Miyamoto
2017 - Vol. 4 p.285-293
General toxicity of a vitamin K1 2,3-epoxide reductase (VKOR) inhibitor, 3-acetyl-5-methyltetronic acid, in rats
Yoko Miyazaki
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
Yoshihiro Mimaki
2014 - Vol. 1 p.169-172
Estimation of endoplasmic reticulum stress-inducing ability of nobiletin, a citrus polymethoxyflavonoid, in SK-N-SH human neuroblastoma cells
Yoshikazu Matsuda
2022 - Vol. 9 p.187-196
Pharmaceutical concentrations and antimicrobial activity using hypersusceptible Escherichia coli lacking TolC component of multidrug efflux system in the Ayase River in Japan
Yu Meng
2018 - Vol. 5 p.123-126
The impact on the activity of acetylcholinesterase of a polylysine-ApoE peptide carrier targeting the blood brain barrier
Yuichi Miki
2015 - Vol. 2 p.111-116
Evaluation of laser irradiance on photodynamic therapy using talaporfin sodium-induced glioblastoma T98G cell death
Yukinori Mera
2021 - Vol. 8 p.37-47
A 90-day oral repeated-dose toxicity study of Monascus Color Y-001 in rats
Yuko Matsushima
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
Yunagi Murase
2023 - Vol. 10 p.209-219
Subchronic oral toxicity study of Monascus Color in beagle dogs

N

Akemichi Nagasawa
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Akira Naganuma
2022 - Vol. 9 p.159-162
Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells
2021 - Vol. 8 p.157-160
Knockdown of deubiquitinating enzyme Usp34 confers resistance to methylmercury in HEK293 cells
2019 - Vol. 6 p.167-170
Methylmercury causes neuronal cell death via M1-microglial activation in organotypic slices prepared from mouse cerebral cortex
2018 - Vol. 5 p.71-73
Putrescine selectively alleviates methylmercury toxicity in C17.2 mouse neural stem cells
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
2017 - Vol. 4 p.41-43
Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells
2017 - Vol. 4 p.37-39
Identification of transcription factors activated by methylmercury in mouse brain
2016 - Vol. 3 p.75-77
Overexpression of palmitoyl transferase HIP14 confers resistance to methylmercury in SH-SY5Y human neuroblastoma cells
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
2015 - Vol. 2 p.245-247
Knockdown of Acyl-CoA thioesterase 9 gene expression by siRNA confers resistance to arsenite in HEK293 cells
2015 - Vol. 2 p.239-243
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
2015 - Vol. 2 p.229-231
Citrulline enhances methylmercury toxicity in HEK293 and C17.2 cells
2015 - Vol. 2 p.227-228
Metabolomic analysis of low molecular weight substances released into medium from HEK293 cells treated with methylmercury
2015 - Vol. 2 p.223-226
Methylmercury induces release of a cytotoxic factor from HEK293 cells into medium
2015 - Vol. 2 p.67-78
Effect of prenatal methylmercury exposure on neurobehavioral development in male mice: comparison between methylmercury in fish and methylmercury chloride added to diets
2014 - Vol. 1 p.161-164
CDC23 knockdown reinforces methylmercury sensitivity in HEK293 cells
2014 - Vol. 1 p.113-114
Identification of growth-dependent genes involved in paraquat toxicity in Saccharomyces cerevisiae
2014 - Vol. 1 p.109-111
Overexpression of RPN8, SKP1, MIA40 or MES1 increases resistance to cadmium in Saccharomyces cerevisiae
2014 - Vol. 1 p.95-99
A screening method for growth-dependent genes involved in the cytotoxicity of chemicals in Saccharomyces cerevisiae
Akito Nagatsu
2019 - Vol. 6 p.25-29
Protective effect of the Kampo formula “Juzen-taiho-to” on isoniazid- and rifampicin-induced hepatotoxicity in mice
2018 - Vol. 5 p.105-112
The Kampo formula “Juzen-taiho-to” exerts protective effects on ethanol-induced liver injury in mice
2017 - Vol. 4 p.261-268
Suppressive effect of Sasa veitchii extract on obesity induced by a high-fat diet through modulation of adipose differentiation in mice
2016 - Vol. 3 p.233-236
Hepatoprotective effect of kampo formula “Juzen-taiho-to” on bromobenzene-induced toxicity in mice
Atsushi Nakamura
2014 - Vol. 1 p.63-72
A 4-week oral toxicity study of L-alanine in rats with a recovery period of 2 weeks
Atsushi Noda
2019 - Vol. 6 p.333-340
Assessment of the acute toxicity of 16 veterinary drugs and a disinfectant to aquatic and soil organisms
2017 - Vol. 4 p.207-218
Toxicity in repeated 28-day oral administration of N-phenyl-1-naphthylamine in rats
Chihiro Noguchi
2020 - Vol. 7 p.85-96
Utility of measuring long bone length in toxicity studies: results of a 14-day repeated dose oral toxicity study of dexamethasone in young, periadolescent and adult rats
Dai Nakae
2021 - Vol. 8 p.221-228
Influence of trans-fatty acids on non-alcoholic steatohepatitis with hepatic fibrosis induced by a choline-deficient, methionine-lowered, L-amino acid-defined diet in male Harlan Sprague Dawley rats
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Daichi Nagai
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Eiko Nagata
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
Erik de Aquino Nery
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
Erik de Aquino Nery
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Haruki Nishino
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Hideki Nishitoh
2022 - Vol. 9 p.179-186
Role of cytoplasmic acetyltransferases, NAA60 and HAT1, in cellular protection against genotoxic agents
Hiroaki Nagaoka
2022 - Vol. 9 p.173-178
Assessment of genotoxicity of 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) in zebrafish (Danio rerio) using the comet assay and micronucleus test
Hiroshi Nagai
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Hisako Nakano
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
Hisamitsu Nagase
2022 - Vol. 9 p.25-30
Erratum: Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2017 - Vol. 4 p.121-126
Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2016 - Vol. 3 p.257-280
DNA microarray analysis of fetal liver of C57BL/6J mice exposed to cadmium during gestation
Hitoshi Naraoka
2016 - Vol. 3 p.19-25
A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Junichi Namekawa
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
2019 - Vol. 6 p.269-275
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats
2018 - Vol. 5 p.13-20
Increased hepatic triglyceride level induced by a glucokinase activator in mice
Junichiro Nagumo
2023 - Vol. 10 p.113-123
A trial to predict skin irritancy of cosmetic products using cytotoxicity tests
Kazuhiko Nakano
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Keisuke Nagata
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
2016 - Vol. 3 p.39-46
Toxicogenomic prediction with graph-based structured regularization on transcription factor network
2015 - Vol. 2 p.161-170
Toxicogenomic prediction with group sparse regularization based on transcription factor network information
Keisuke Namekawa
2020 - Vol. 7 p.141-152
Maltosyltrehalose Syrup: Bacterial reverse mutation test, and 90-day feeding and 90-day repeated oral dose toxicity studies in rats
2019 - Vol. 6 p.299-317
Glucosyl hesperidin: safety studies
Kiyomitsu Nemoto
2014 - Vol. 1 p.169-172
Estimation of endoplasmic reticulum stress-inducing ability of nobiletin, a citrus polymethoxyflavonoid, in SK-N-SH human neuroblastoma cells
Kiyoshi Nagata
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Kota Nakajima
2023 - Vol. 10 p.315-323
Flunitrazepam alters the toxicokinetics of chlorpromazine enhancing its toxicity
Kunihiko Nakai
2015 - Vol. 2 p.67-78
Effect of prenatal methylmercury exposure on neurobehavioral development in male mice: comparison between methylmercury in fish and methylmercury chloride added to diets
Kunihiko Nishino
2022 - Vol. 9 p.187-196
Pharmaceutical concentrations and antimicrobial activity using hypersusceptible Escherichia coli lacking TolC component of multidrug efflux system in the Ayase River in Japan
Ma Ning
2015 - Vol. 2 p.9-17
Effects of sub-chronic exposure to deltamethrin on shuttle-box avoidance and contents of amino acid neurotransmitters in hippocampus of mice
Mai Nishikawa
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Maki Nakamura
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Mari Nakamura
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Marinetes Dantas de Aquino Nery
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Masaaki Nagano
2021 - Vol. 8 p.243-248
Intake of wheat bran after administration of methylmercury reduces mercury accumulation in mice
Masakatsu Natsume
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
2019 - Vol. 6 p.341-357
Safety assessment of isomaltodextrin-producing enzymes from Paenibacillus alginolyticus
Masaki Nishikawa
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Masako Nakamura
2019 - Vol. 6 p.217-224
Recovery of increased weights of the liver and kidneys by cessation of D-allulose feeding in Wistar rats
Masaru Naito
2018 - Vol. 5 p.21-32
Comparison of stabilities of nitrenium ions and in vitro and in vivo genotoxic potential, between four aniline derivatives
Masataka Nomoto
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
Mayuko Nagamura
2022 - Vol. 9 p.197-202
Transient increase in plasma urate induced by a single oral dose of fructose in rats
Mie Naruse
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
Miki Nishi
2021 - Vol. 8 p.183-187
Improvement of a fish holding device for oral administration to zebrafish
Mikio Nakamura
2023 - Vol. 10 p.209-219
Subchronic oral toxicity study of Monascus Color in beagle dogs
Mikiya Nakatani
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
Mizuki Nakamura
2023 - Vol. 10 p.1-6
PPAR gamma negatively regulates the expression of TRPM8 in normal epidermal cells but mutually regulate their expressions with TRPM8 by feed-back loop regulation in squamous carcinoma cells
Momoko Noguchi
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
Moussa Ndong
2018 - Vol. 5 p.87-91
Cadmium, arsenic and lead accumulation in rice grains produced in Senegal river valley
Nanako Niikura
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Naoe Nishimura
2024 - Vol. 11 p.57-67
Effects of food restriction for 3 or 7 days on toxicity-related parameters in rats
Naoto Noguchi
2014 - Vol. 1 p.151-159
Safety evaluation of mutagenecity, acute and subacute toxicity study of Chlorella vulgaris CK-22 in rats
Randy Novirsa
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Rikio Niki
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
Ryota Nakano
2023 - Vol. 10 p.7-20
Paternal exposure to methylphenidate induces ADHD-like behavioral phenotypes and altered gene expressions in mouse offspring
Ryota Nomura
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Sae Nakane
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
Satoshi Numazawa
2023 - Vol. 10 p.315-323
Flunitrazepam alters the toxicokinetics of chlorpromazine enhancing its toxicity
2023 - Vol. 10 p.179-187
Effect of blood collection tubes containing separation gels on the measurement of drug concentrations in clinical toxicology
2023 - Vol. 10 p.7-20
Paternal exposure to methylphenidate induces ADHD-like behavioral phenotypes and altered gene expressions in mouse offspring
2021 - Vol. 8 p.249-260
Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture
2021 - Vol. 8 p.229-233
Time-dependent changes in serum concentrations of acyclovir and its metabolite, 9-carboxymethoxymethylguanine, in a patient with suspected acyclovir encephalopathy
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Shingo Nemoto
2019 - Vol. 6 p.245-248
Comparison of cytotoxicity between fixed- and unfixed-combination ophthalmic solutions in vitro
2018 - Vol. 5 p.83-85
Risk assessment of reproductive and developmental toxicity in eye-drop drugs: a consideration based on threshold of toxicological concern
2017 - Vol. 4 p.105-107
A study for finding new phototoxicity descriptors related to potential energy
2015 - Vol. 2 p.147-153
In vitro comet assay in cultured human corneal epithelial cells
Shinichi Nonaka
2021 - Vol. 8 p.183-187
Improvement of a fish holding device for oral administration to zebrafish
Takahito Nishiyama
2019 - Vol. 6 p.107-112
Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction
Takamasa Numano
2017 - Vol. 4 p.137-150
No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice
Takanori Nakamura
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Takehiro Nakamura
2021 - Vol. 8 p.147-155
Relationship between renal dysfunction and change in serum electrolyte levels in patients administered with liposomal amphotericin B
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
Takuya Nagao
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Takuya Ninoseki
2018 - Vol. 5 p.21-32
Comparison of stabilities of nitrenium ions and in vitro and in vivo genotoxic potential, between four aniline derivatives
Takuya Nishimura
2023 - Vol. 10 p.69-82
A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
2023 - Vol. 10 p.59-68
A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats
Takuya Noguchi
2022 - Vol. 9 p.159-162
Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells
Teruko Nagi
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Tetsuji Nagao
2015 - Vol. 2 p.79-82
Motor activities of newborns prenatally exposed to low-dose bisphenol A in diverse mouse strains
2015 - Vol. 2 p.37-39
Effects of prenatal exposure to low doses of diethylstilbestrol on motor activity in newborn mice
Tetsuji Nishimura
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Tetsuya Nakamura
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Tohru Nagahama
2023 - Vol. 10 p.113-123
A trial to predict skin irritancy of cosmetic products using cytotoxicity tests
Toshimasa Nishiyama
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Toshio Nishikawa
2021 - Vol. 8 p.69-73
Evaluation of the in vitro cytotoxicity of oscillatoxins E and F under nutrient-starvation culture conditions
Tsukasa Negura
2017 - Vol. 4 p.15-21
Normal ovarian aging, but modified T-cell differentiation, in female mice following neonatal exposure to bisphenol A
Tsunemasa Nonogaki
2017 - Vol. 4 p.261-268
Suppressive effect of Sasa veitchii extract on obesity induced by a high-fat diet through modulation of adipose differentiation in mice
2016 - Vol. 3 p.233-236
Hepatoprotective effect of kampo formula “Juzen-taiho-to” on bromobenzene-induced toxicity in mice
Tsutomu Negama
2020 - Vol. 7 p.105-114
Evaluation of cytokine storms in a disseminated intravascular coagulation monkey model
Tsuyoshi Nakanishi
2022 - Vol. 9 p.25-30
Erratum: Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2017 - Vol. 4 p.121-126
Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
Tsuyoshi Nakano
2020 - Vol. 7 p.77-83
Arsenite inhibits gene expression of perlecan, syndecan-1, -2, -3 and biglycan in cultured vascular endothelial cells
Willy Cahya Nugraha
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Yasuharu Nakanishi
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Yorifumi Nishihori
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
Yoshihiko Nishino
2020 - Vol. 7 p.171-176
The aminoethyl group is a crucial structural moiety in metal-mediated oxidative DNA damage by catecholamines
Yuhei Nishimura
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Yuka Nagatsuka
2023 - Vol. 10 p.325-333
Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Yuki Nakamura
2021 - Vol. 8 p.249-260
Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture
Yuki Nishiyama
2021 - Vol. 8 p.189-193
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity
Yukiko Naito
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Yutaka Nakanishi
2020 - Vol. 7 p.85-96
Utility of measuring long bone length in toxicity studies: results of a 14-day repeated dose oral toxicity study of dexamethasone in young, periadolescent and adult rats
Yuuka Nakatani
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats

O

Atsushi Ono
2019 - Vol. 6 p.125-136
Validation of the statistical parameters and model selection criteria of the benchmark dose methods for the evaluation of various endpoints in repeated-dose toxicity studies
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
2015 - Vol. 2 p.177-190
Repeated dose and reproductive/developmental toxicity of long-chain perfluoroalkyl carboxylic acids in rats: perfluorohexadecanoic acid and perfluorotetradecanoic acid
Emiko Okazaki
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Emiko Ozeki
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Fumihiko Ogata
2021 - Vol. 8 p.147-155
Relationship between renal dysfunction and change in serum electrolyte levels in patients administered with liposomal amphotericin B
Hana Ohtani
2014 - Vol. 1 p.123-129
The paradoxical effect of 1,4-naphthoquinone on the process of cell death induced by hydrogen peroxide in rat thymocytes
Harumi Okuyama
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Hideharu Ochiai
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
Hideo Ohmukai
2017 - Vol. 4 p.15-21
Normal ovarian aging, but modified T-cell differentiation, in female mice following neonatal exposure to bisphenol A
Hiromu Okano
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Hiroyuki Ohnishi
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
Hiroyuki Okazaki
2017 - Vol. 4 p.195-200
Expression levels of 39 Cyp mRNAs in the mouse brain and neuroblastoma cell lines, C-1300N18 and NB2a – strong expression of Cyp1b1
2016 - Vol. 3 p.55-61
HU-210, a synthetic analog of Δ9-THC, is not a modifier of estrogen signaling in MCF-7 human breast cancer cells
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Jun Okawa
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
Kaho Ozaki
2015 - Vol. 2 p.37-39
Effects of prenatal exposure to low doses of diethylstilbestrol on motor activity in newborn mice
Katsumi Ohtani
2019 - Vol. 6 p.113-116
Impairment of fertilization efficiency in mice following nano-sized titanium exposure
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Katsutoshi Ohno
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
Kei Ohkubo
2019 - Vol. 6 p.217-224
Recovery of increased weights of the liver and kidneys by cessation of D-allulose feeding in Wistar rats
Keisuke Oyama
2017 - Vol. 4 p.173-178
Cytometric analysis on cytotoxicity of 4,4′-methylenediphenyl diisocyanate, a chemical allergen, in rat thymocytes
Kengo Ogata
2022 - Vol. 9 p.85-93
Occupational exposure of pharmacists to drugs during tablet crushing and its countermeasures
Kenichiro Ogura
2019 - Vol. 6 p.107-112
Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction
Kozo Omichi
2014 - Vol. 1 p.39-47
Safety evaluation of morphological changes in corneal endothelial cells induced by K-115 in cynomolgus monkeys
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Kumiyo Okada
2024 - Vol. 11 p.57-67
Effects of food restriction for 3 or 7 days on toxicity-related parameters in rats
Kunihiro Ohta
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Makoto Osabe
2023 - Vol. 10 p.265-277
Differential expression of Cytochrome P450 1A2 in simple fatty liver and steatohepatitis
Mari Okazaki
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Masahiro Ogawa
2020 - Vol. 7 p.133-139
Sex differences in the effects of high-fat diet on mouse sciatic nerves
2020 - Vol. 7 p.115-121
Effects of estrogen on fatty-acid-induced cytotoxicity in mouse Neuro-2a neural cells
Masahiro Okada
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Masahiro Okamoto
2015 - Vol. 2 p.155-159
Effects of rofecoxib on lipid oxidation in plasma and aortas of rats
Masahito Ohara
2019 - Vol. 6 p.333-340
Assessment of the acute toxicity of 16 veterinary drugs and a disinfectant to aquatic and soil organisms
2017 - Vol. 4 p.207-218
Toxicity in repeated 28-day oral administration of N-phenyl-1-naphthylamine in rats
Masaki Okunaga
2018 - Vol. 5 p.87-91
Cadmium, arsenic and lead accumulation in rice grains produced in Senegal river valley
Masaru Ochiai
2019 - Vol. 6 p.217-224
Recovery of increased weights of the liver and kidneys by cessation of D-allulose feeding in Wistar rats
Masato Ohbuchi
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Masaya Ohta
2023 - Vol. 10 p.325-333
Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Naohito Ohno
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
Naoki Ohara
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Naoko Oya
2017 - Vol. 4 p.201-205
Organophosphorus insecticide dichlorvos inhibits fatty acid amide hydrolase in the male reproductive organs of rats
Osamu Ohgoda
2020 - Vol. 7 p.55-76
Toxicological evaluation of DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine)
Reo Odagiri
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Risa Ogawa
2017 - Vol. 4 p.195-200
Expression levels of 39 Cyp mRNAs in the mouse brain and neuroblastoma cell lines, C-1300N18 and NB2a – strong expression of Cyp1b1
Ryo Ohta
2017 - Vol. 4 p.15-21
Normal ovarian aging, but modified T-cell differentiation, in female mice following neonatal exposure to bisphenol A
Ryosuke Ota
2021 - Vol. 8 p.147-155
Relationship between renal dysfunction and change in serum electrolyte levels in patients administered with liposomal amphotericin B
Ryota Ojiro
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Ryuichi Ono
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
Saki Ohkawa
2024 - Vol. 11 p.11-15
Indeterminate alteration of TRPM8 and p21/Cip1 levels in normal human keratinocytes by incubating with medium including substances released by squamous carcinoma cells
2023 - Vol. 10 p.1-6
PPAR gamma negatively regulates the expression of TRPM8 in normal epidermal cells but mutually regulate their expressions with TRPM8 by feed-back loop regulation in squamous carcinoma cells
2021 - Vol. 8 p.17-22
Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15
Satomi Onosaka
2016 - Vol. 3 p.151-156
Zinc sulfate pretreatment prevents carbon tetrachloride-induced lethal toxicity through metallothionein-mediated suppression of lipid peroxidation in mice
Shigeru Oshio
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
Shin Ohtani
2024 - Vol. 11 p.27-35
Development of an in vivo pain assessment method for exposure to intermediate-frequency magnetic fields
Shuji Ogawa
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
2016 - Vol. 3 p.19-25
A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Shunsuke Okajima
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
2015 - Vol. 2 p.233-238
(–)-Xanthatin-mediated marked up-regulation of RhoB, a sensor for damaged DNA
Tadashi Okobira
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Takafumi Oshikata
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats
Takahiro Ochiya
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
Takako Ohkura
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Takanori Ohkubo
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
Takashi Ohki
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Takashi Ohura
2014 - Vol. 1 p.101-108
Sex-dependent difference in the hepatic and pulmonary toxicological effects in mice administrated 7-chlorinated benz[a]anthracene
Takayuki Okamura
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats
Takuo Ogihara
2020 - Vol. 7 p.9-14
Usefulness and limitations of mRNA measurement in HepaRG cells for evaluation of cytochrome P450 induction
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Tetsuo Ogawa
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
Tomoaki Okuda
2022 - Vol. 9 p.117-122
Leaf extracts from Camellia sinensis and Argania spinosa suppress oxidative stress and chemokine release in human 3-dimensional cultured epidermis exposed to PM2.5 collected with cyclonic separation
Tomokazu Ohnuma
2019 - Vol. 6 p.107-112
Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction
Tomoko Okada
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Toshiya Okamura
2014 - Vol. 1 p.63-72
A 4-week oral toxicity study of L-alanine in rats with a recovery period of 2 weeks
Toshiyuki Oshima
2021 - Vol. 8 p.17-22
Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15
2018 - Vol. 5 p.203-207
Cyclin-dependent kinase inhibitor p21/Cip1 down-regulates the expression of proteasome activator PA28γ in normal hepatocyte-derived cells
Wataru Ochiai
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Yasufumi Ota
2016 - Vol. 3 p.1-8
Physiological conditions in iPRECIO® -implanted rats
Yasumitsu Ogra
2021 - Vol. 8 p.61-67
Effects of hemoglobin on post-mortem oxidation of bromazepam
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
2019 - Vol. 6 p.181-185
Species difference in antimony and arsenic metabolism between hamster and rat after administration of tri- or pentavalent inorganic antimony
2015 - Vol. 2 p.95-99
Metabolism of trimethylselenonium ion in selenium accumulator, Allium sativum
Yasuo Ohno
2020 - Vol. 7 p.249-252
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
Yasuo Oyama
2017 - Vol. 4 p.173-178
Cytometric analysis on cytotoxicity of 4,4′-methylenediphenyl diisocyanate, a chemical allergen, in rat thymocytes
2016 - Vol. 3 p.121-125
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes
2015 - Vol. 2 p.217-222
Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes
2015 - Vol. 2 p.209-216
Zn2+-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-n-octyl-4-isothiazolin-3-one in rat thymocytes
2014 - Vol. 1 p.123-129
The paradoxical effect of 1,4-naphthoquinone on the process of cell death induced by hydrogen peroxide in rat thymocytes
Yasushi Ohizumi
2014 - Vol. 1 p.169-172
Estimation of endoplasmic reticulum stress-inducing ability of nobiletin, a citrus polymethoxyflavonoid, in SK-N-SH human neuroblastoma cells
Yasutaka Ogawa
2014 - Vol. 1 p.135-142
Effects of a repeated low dose of LiCl injection under conditioned taste/flavor aversion using xylene
Yasuteru Otagiri
2022 - Vol. 9 p.103-110
Fecal microRNA223 as an indicator of recovery in chronic DSS colitis model in rats
2021 - Vol. 8 p.177-182
Expression of miRNAs in the colon, rectum, plasma, and feces in rats with dextran sulfate sodium
Yasuyuki Ohnishi
2023 - Vol. 10 p.301-306
Derivation of the permitted daily exposure value for p-tert-butylphenol as an impurity in pharmaceutical products
2023 - Vol. 10 p.295-300
Derivation of permitted daily exposure value for 1,8-diazabicyclo[5.4.0]undec-7-ene in pharmaceutical products
2016 - Vol. 3 p.243-250
Safety assessment of probiotic bacteria, Bacillus coagulans strain SANK70258, in rats
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Yoshinori Okamoto
2020 - Vol. 7 p.171-176
The aminoethyl group is a crucial structural moiety in metal-mediated oxidative DNA damage by catecholamines
2014 - Vol. 1 p.73-79
Effects of organic and inorganic mercury(II) on gene expression via DNA conformational changes
Yousuke Ogiwara
2016 - Vol. 3 p.75-77
Overexpression of palmitoyl transferase HIP14 confers resistance to methylmercury in SH-SY5Y human neuroblastoma cells
Yuji Oishi
2016 - Vol. 3 p.19-25
A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Yurie Ogihara
2015 - Vol. 2 p.95-99
Metabolism of trimethylselenonium ion in selenium accumulator, Allium sativum
Yurie Ohiwa
2015 - Vol. 2 p.217-222
Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes
Yuya Okayama
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023

P

Cao Pei
2015 - Vol. 2 p.9-17
Effects of sub-chronic exposure to deltamethrin on shuttle-box avoidance and contents of amino acid neurotransmitters in hippocampus of mice
Gao Peng
2015 - Vol. 2 p.9-17
Effects of sub-chronic exposure to deltamethrin on shuttle-box avoidance and contents of amino acid neurotransmitters in hippocampus of mice
Gennady E. Platoff Jr.
2016 - Vol. 3 p.195-204
Acute toxicity of phorate oxon by oral gavage in the Sprague-Dawley rat
Jiang Pu
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Kalathil Sadasivan Pillai
2024 - Vol. 11 p.1-10
Repeated dose administration toxicity studies - Use of t-tests in multiplicity data analysis
Perayot Pamonsinlapatham
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Quang Dinh Phan
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
Weston W. Porter
2020 - Vol. 7 p.189-199
Postnatal wheel running mitigates endocrine disruption of mammary gland development in mice

Q

Dan Qin
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Jing Qian
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Mary L. S. Queiroz
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Naisong Qi
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Sabina Quader
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
Yuwen Qiu
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts

R

Alan Blake Richards
2019 - Vol. 6 p.299-317
Glucosyl hesperidin: safety studies
Dipankar Chandra Roy
2023 - Vol. 10 p.137-141
mRNA expression levels of CCL4, IL6, and CXCL2 in multiwalled carbon nanotube induced lung tumors in rats
Ian N. Robinson
2020 - Vol. 7 p.55-76
Toxicological evaluation of DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine)
Katsunori Ryoke
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
Rayane de Tasso Moreira Ribeiro
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
Rayane de Tasso Moreira Ribeiro
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Roger A. Renne
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats

S

Akinari Shimada
2022 - Vol. 9 p.197-202
Transient increase in plasma urate induced by a single oral dose of fructose in rats
Andrey Santos
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
Atsushi Sakamoto
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Atsushi Shiga
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Aya Sato
2015 - Vol. 2 p.111-116
Evaluation of laser irradiance on photodynamic therapy using talaporfin sodium-induced glioblastoma T98G cell death
Ayako Sakai
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
Azumi Sato
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Benedikt Scheidecker
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Daisuke Sasaki
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
Eiko Shimaya
2020 - Vol. 7 p.253-257
Electromagnetic fields (EMF) facilitate cell migration and BrdU incorporation during an EMF-sensitive phase in a rat neurosphere assay in vitro
2016 - Vol. 3 p.101-108
Major histocompatibility complex expression in a rotenone model of Parkinson’s disease in rats
Eito Shimizu
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
Emily E. Schmitt
2020 - Vol. 7 p.189-199
Postnatal wheel running mitigates endocrine disruption of mammary gland development in mice
Erina Shiraishi
2022 - Vol. 9 p.25-30
Erratum: Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2017 - Vol. 4 p.121-126
Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
Genki Sakai
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Hana Shimizu-Furusawa
2016 - Vol. 3 p.185-193
Neurobehavioral toxicity related to the exposure of weaning mice to low-level mercury vapor and methylmercury and influence of aging
Harumi Sakuda
2020 - Vol. 7 p.167-170
Bacteriological evaluation of feasibility of food poisoning from long-term stored “pack-cooked” meals
Hidekazu Suzuki
2018 - Vol. 5 p.21-32
Comparison of stabilities of nitrenium ions and in vitro and in vivo genotoxic potential, between four aniline derivatives
Hideki Serizawa
2017 - Vol. 4 p.247-259
Toxicity of repeated 28-day oral administration of acenaphthylene in rats
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
Hideki Shiratsuchi
2022 - Vol. 9 p.61-69
Potential human health risks of mercury-contaminated cassavas – Preliminary studies
Hideyuki Sakaki
2018 - Vol. 5 p.141-147
Anatomical and histological sex differences in the eye and its accessory tissues in Dutch belted rabbits
2017 - Vol. 4 p.105-107
A study for finding new phototoxicity descriptors related to potential energy
2017 - Vol. 4 p.95-99
Repeated-dose ocular instillation toxicity study: a survey of its study design on the basis of common technical documents in Japan
2016 - Vol. 3 p.217-232
Ocular instillation toxicity study: current status and points to consider on study design and evaluation
2015 - Vol. 2 p.147-153
In vitro comet assay in cultured human corneal epithelial cells
Hirokatsu Saito
2021 - Vol. 8 p.169-175
Development of an inhalation exposure system of a pressurized metered-dose inhaler (pMDI) formulation for small experimental animals
Hiroki Sasaki
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
Hiroki Shioda
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Hiroshi Satoh
2015 - Vol. 2 p.67-78
Effect of prenatal methylmercury exposure on neurobehavioral development in male mice: comparison between methylmercury in fish and methylmercury chloride added to diets
Hiroshi Suzuki
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
2019 - Vol. 6 p.145-165
Comprehensive toxicity evaluation of cyclopentyl methyl ether (CPME) for establishing a permitted daily exposure level
Hiroyuki Sakakibara
2014 - Vol. 1 p.101-108
Sex-dependent difference in the hepatic and pulmonary toxicological effects in mice administrated 7-chlorinated benz[a]anthracene
Hisakazu Sanada
2023 - Vol. 10 p.307-313
Derivation of permitted daily exposure value for trifluoroacetic acid as an impurity in pharmaceutical products
2023 - Vol. 10 p.301-306
Derivation of the permitted daily exposure value for p-tert-butylphenol as an impurity in pharmaceutical products
2023 - Vol. 10 p.295-300
Derivation of permitted daily exposure value for 1,8-diazabicyclo[5.4.0]undec-7-ene in pharmaceutical products
Ikuro Suzuki
2022 - Vol. 9 p.203-209
An in vitro microfluidic culture device for peripheral neurotoxicity prediction at low concentrations based on deep learning
Jie Song
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Jin Suzuki
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
K.J. Senthil Kumar
2016 - Vol. 3 p.205-216
In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)
Kaoru Sato
2014 - Vol. 1 p.87-94
Residual metals in carbon nanotubes suppress the proliferation of neural stem cells
Kayoko Shimoi
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
2014 - Vol. 1 p.101-108
Sex-dependent difference in the hepatic and pulmonary toxicological effects in mice administrated 7-chlorinated benz[a]anthracene
Kazue Sakemi-Hoshikawa
2020 - Vol. 7 p.249-252
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
Kazumi Sugihara
2016 - Vol. 3 p.177-183
Estimation of occupational exposure to drugs during tablet crushing
Kazutoshi Sugita
2021 - Vol. 8 p.49-52
Acrylamide in dog food
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
Kazuyo Sadamoto
2019 - Vol. 6 p.245-248
Comparison of cytotoxicity between fixed- and unfixed-combination ophthalmic solutions in vitro
2018 - Vol. 5 p.83-85
Risk assessment of reproductive and developmental toxicity in eye-drop drugs: a consideration based on threshold of toxicological concern
2015 - Vol. 2 p.147-153
In vitro comet assay in cultured human corneal epithelial cells
Kei-ichi Sugiyama
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
Ken Shirato
2014 - Vol. 1 p.115-121
Diallyl disulfide administration increases the number of B-lymphocytes in the rat spleen
Kenichiro Suzuki
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
Kiyoshi Shibuya
2017 - Vol. 4 p.269-273
Effect of metallothionein on ethanol-induced hepatotoxicity in mice
Kiyoshi Sugiyama
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Koki Sugimoto
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Kousuke Suga
2022 - Vol. 9 p.17-21
A novel high-purity carbon-nanotube yarn electrode used to obtain biopotential measurements in small animals: flexible, wearable, less invasive, and gel-free operation
Kouta Sugizaki
2021 - Vol. 8 p.17-22
Ouabagenin, an aglycone of cardiotonic steroid ouabain, functions as LXR ligand but avoids the increase in the SREBP-1 by inducing Krüppel-like factor 15
Kyhota Shida
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Li Su
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Linlin Shao
2023 - Vol. 10 p.279-285
K16ApoE interrupts cerebral blood flow and induces blood cell aggregation in mice
2023 - Vol. 10 p.125-131
K16ApoE inhibits the activity of acetylcholinesterase but is not the primary toxicological mechanism in mice
Mai Sasaki
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
Mai Shoji
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Mai Sugi
2019 - Vol. 6 p.341-357
Safety assessment of isomaltodextrin-producing enzymes from Paenibacillus alginolyticus
Makoto Shibutani
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
2018 - Vol. 5 p.167-170
Derivation of acceptable daily exposure value for alanine, N,N-bis(carboxymethyl)-, trisodium salt
Mario J. A. Saad
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
Masahiko Satoh
2023 - Vol. 10 p.133-136
Effect of cadmium on expression of BIRC family genes in HeLa cells
2018 - Vol. 5 p.93-97
Effect of heat shock protein gene expression on cadmium toxicity in human proximal tubular cells
2017 - Vol. 4 p.275-278
Effect of chronic cadmium exposure on the gene expression of Birc family in the mouse kidney and liver
2017 - Vol. 4 p.269-273
Effect of metallothionein on ethanol-induced hepatotoxicity in mice
2016 - Vol. 3 p.285-289
Sensitivity of MT-III null mice upon chronic exposure to cadmium
2016 - Vol. 3 p.281-284
Cadmium-induced protein ubiquitination in UBA80 knockdown HK-2 cells
2016 - Vol. 3 p.257-280
DNA microarray analysis of fetal liver of C57BL/6J mice exposed to cadmium during gestation
2016 - Vol. 3 p.185-193
Neurobehavioral toxicity related to the exposure of weaning mice to low-level mercury vapor and methylmercury and influence of aging
2015 - Vol. 2 p.259-262
The enhancement effect of HIST1H4C knockdown on cadmium toxicity in human proximal tubular cells
2014 - Vol. 1 p.165-167
The involvement of GPRC5B in cadmium toxicity in HK-2 cells
2014 - Vol. 1 p.131-133
Effects of cadmium on the gene expression of SLC39A1 coding for ZIP1 protein
Masami Shimoda
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Masanaho Sasatsu
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
Masashi Sekimoto
2022 - Vol. 9 p.167-172
Induction of CYP3A4 mRNA by cooked food-derived carcinogenic heterocyclic aromatic amines in human HPL-A3 cells
2021 - Vol. 8 p.49-52
Acrylamide in dog food
Masato Sasaki
2023 - Vol. 10 p.241-247
Effects of expression of the 10-formyltetrahydrofolate metabolizing enzyme ALDH1L1 on pyrimidine nucleotide synthesis and the salvage pathway
Masayuki Sato
2018 - Vol. 5 p.71-73
Putrescine selectively alleviates methylmercury toxicity in C17.2 mouse neural stem cells
Masayuki Seki
2017 - Vol. 4 p.1-7
Simultaneous depletion of WRNIP1 and RAD52 restores resistance to oxidative stress
Masumi Suzui
2023 - Vol. 10 p.137-141
mRNA expression levels of CCL4, IL6, and CXCL2 in multiwalled carbon nanotube induced lung tumors in rats
2023 - Vol. 10 p.27-30
mRNA expression profile of cytokines in rat primary alveolar macrophages treated with multiwalled carbon nanotube (MWCNT)
Mayuko Suguro
2017 - Vol. 4 p.137-150
No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice
Mayumi Sugimoto
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Megumi Sakata
2023 - Vol. 10 p.199-208
Investigation of the maximum feasible volume of subretinal injections into rat and cynomolgus monkey eyes
2023 - Vol. 10 p.157-167
Evaluation of maximal dosing volume for intravitreal injections in cynomolgus monkeys
Megumi Suda
2018 - Vol. 5 p.153-159
In utero exposure to 2,2’,4,4’,5,5’-hexachlorobiphenyl accelerates the onset of eye opening in rat offspring
2015 - Vol. 2 p.249-258
Developmental changes in associative learning behavior in male rats
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Mika Senuma
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
Mikio Sasaki
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Minoru Sasaki
2020 - Vol. 7 p.85-96
Utility of measuring long bone length in toxicity studies: results of a 14-day repeated dose oral toxicity study of dexamethasone in young, periadolescent and adult rats
Mitsuru Shindo
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
2015 - Vol. 2 p.233-238
(–)-Xanthatin-mediated marked up-regulation of RhoB, a sensor for damaged DNA
Mitsuyuki Shirai
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
2018 - Vol. 5 p.13-20
Increased hepatic triglyceride level induced by a glucokinase activator in mice
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Mituru Sugiyama
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023
Miyoko Saito
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
Mizuki Sato
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Momoko Sunouchi
2020 - Vol. 7 p.249-252
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Motonori Sugiyama
2021 - Vol. 8 p.229-233
Time-dependent changes in serum concentrations of acyclovir and its metabolite, 9-carboxymethoxymethylguanine, in a patient with suspected acyclovir encephalopathy
Nahida Sultana
2023 - Vol. 10 p.137-141
mRNA expression levels of CCL4, IL6, and CXCL2 in multiwalled carbon nanotube induced lung tumors in rats
2023 - Vol. 10 p.27-30
mRNA expression profile of cytokines in rat primary alveolar macrophages treated with multiwalled carbon nanotube (MWCNT)
Naoko Satoh
2016 - Vol. 3 p.13-18
Hepatitis C virus core can induce lipid droplet formation in a yeast model system
Naoto Shimizu
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Naoya Sonoda
2014 - Vol. 1 p.113-114
Identification of growth-dependent genes involved in paraquat toxicity in Saccharomyces cerevisiae
Narumi Sugihara
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Niti Sharma
2016 - Vol. 3 p.9-12
Single dose oral toxicity study of Picrorhiza kurroa rhizome extract in Wistar rats
Nobuaki Shimada
2014 - Vol. 1 p.101-108
Sex-dependent difference in the hepatic and pulmonary toxicological effects in mice administrated 7-chlorinated benz[a]anthracene
Nobuaki Shirai
2019 - Vol. 6 p.249-252
Localization of the trichloroethylene-related compound S-(1, 2-dichlorovinyl)-L-cysteine in mouse cartilage
Nobuhiro Shimojo
2015 - Vol. 2 p.171-175
Health survey of workers in a 2,4,6-trinitrotoluene explosives factory in Fuxin, China
Nobuyuki Shibata
2023 - Vol. 10 p.241-247
Effects of expression of the 10-formyltetrahydrofolate metabolizing enzyme ALDH1L1 on pyrimidine nucleotide synthesis and the salvage pathway
Noriko Suzuki-Kemuriyama
2021 - Vol. 8 p.221-228
Influence of trans-fatty acids on non-alcoholic steatohepatitis with hepatic fibrosis induced by a choline-deficient, methionine-lowered, L-amino acid-defined diet in male Harlan Sprague Dawley rats
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
Norimasa Senzaki
2015 - Vol. 2 p.201-208
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient
Noriyuki Suzuki
2019 - Vol. 6 p.181-185
Species difference in antimony and arsenic metabolism between hamster and rat after administration of tri- or pentavalent inorganic antimony
Omoko Shindo
2017 - Vol. 4 p.15-21
Normal ovarian aging, but modified T-cell differentiation, in female mice following neonatal exposure to bisphenol A
Osamu Saika
2021 - Vol. 8 p.183-187
Improvement of a fish holding device for oral administration to zebrafish
Pasjan Satrimafitrah
2022 - Vol. 9 p.179-186
Role of cytoplasmic acetyltransferases, NAA60 and HAT1, in cellular protection against genotoxic agents
Raku Shinkyo
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Reiko Suzuki
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
Rie Shoji
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Ryosuke Sato
2021 - Vol. 8 p.7-16
Genotoxicity of Monascus Color Y-001
Ryuhei Sano
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
Sakae Sakamoto
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Sara T. Olalla Saad
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Sawako Sakuratani
2019 - Vol. 6 p.125-136
Validation of the statistical parameters and model selection criteria of the benchmark dose methods for the evaluation of various endpoints in repeated-dose toxicity studies
Sawako Shindo
2021 - Vol. 8 p.157-160
Knockdown of deubiquitinating enzyme Usp34 confers resistance to methylmercury in HEK293 cells
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Seigo Sanoh
2020 - Vol. 7 p.33-40
Triphenyltin inhibits GA-binding protein α nuclear translocation
Seishiro Sakamoto
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
Seiya Shino
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Seong S. Seo
2019 - Vol. 6 p.45-56
Cytotoxic effects of parathion, paraoxon, and their methylated derivatives on a mouse neuroblastoma cell line NB41A3
Shin-ichi Sato
2020 - Vol. 7 p.105-114
Evaluation of cytokine storms in a disseminated intravascular coagulation monkey model
Shin-ichi Sekizawa
2017 - Vol. 4 p.241-245
In vitro genotoxicity test package of antibiotics for human use submitted to the Japanese regulatory agency during 2004–2015
Shinichi Saito
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
Shinsuke Shinoda
2016 - Vol. 3 p.27-31
Quantitative analysis of the relationship between the LLNA:DAE method results and the LLNA EC3 values highlights the connection between the elicitation and induction phases during skin sensitization
Shohei Saito
2015 - Vol. 2 p.217-222
Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes
Shoichiro Sugai
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
2018 - Vol. 5 p.21-32
Comparison of stabilities of nitrenium ions and in vitro and in vivo genotoxic potential, between four aniline derivatives
2017 - Vol. 4 p.9-14
Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs
Shuichi Sekine
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Soichiro Sekiguchi
2018 - Vol. 5 p.153-159
In utero exposure to 2,2’,4,4’,5,5’-hexachlorobiphenyl accelerates the onset of eye opening in rat offspring
Taiki Sugiyama
2021 - Vol. 8 p.37-47
A 90-day oral repeated-dose toxicity study of Monascus Color Y-001 in rats
Takahiro Sugihara
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Takaki Shimono
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Takami Suzuki
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Takamitsu Sasaki
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Takashi Sugimoto
2023 - Vol. 10 p.325-333
Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Takasumi Shimomoto
2021 - Vol. 8 p.97-101
Antidiabetic agent did not impair spermatogenesis in spontaneously hyperglycemic and diabetic rats
2019 - Vol. 6 p.269-275
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys
2019 - Vol. 6 p.259-268
A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats
Takefumi Sagara
2023 - Vol. 10 p.233-240
Coffee diterpenes, cafestol and kahweol, display cytotoxicity and all-trans retinoic acid-induced superoxide generating activity-enhancing ability in U937 cells
2022 - Vol. 9 p.151-157
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
Takehito Suzuki
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
Takeo Sasamoto
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
Takeshi Sakamoto
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Takuji Suzuki
2019 - Vol. 6 p.15-23
Supplementation with lower doses of EGCg reduces liver injury markers of type 2 diabetic rats
Takumi Sekine
2022 - Vol. 9 p.187-196
Pharmaceutical concentrations and antimicrobial activity using hypersusceptible Escherichia coli lacking TolC component of multidrug efflux system in the Ayase River in Japan
Tetsuya Suzuki
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Thiala Soares Josino da Silva
2014 - Vol. 1 p.15-18
Cytotoxic activity and abdominal writhes promoted by snake venom from Philodryas nattereri Steindachner, 1870
Thomas H. Snider
2016 - Vol. 3 p.195-204
Acute toxicity of phorate oxon by oral gavage in the Sprague-Dawley rat
Tomohiro Saito
2021 - Vol. 8 p.229-233
Time-dependent changes in serum concentrations of acyclovir and its metabolite, 9-carboxymethoxymethylguanine, in a patient with suspected acyclovir encephalopathy
Tomoya Shinohara
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
Tomoyuki Sato
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Toshikazu Shiba
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Toshinari Suzuki
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Toshiyuki Shoda
2017 - Vol. 4 p.9-14
Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs
Toshiyuki Suzuki
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Tsutomu Shiroya
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Tsuyoshi Sadakiyo
2019 - Vol. 6 p.341-357
Safety assessment of isomaltodextrin-producing enzymes from Paenibacillus alginolyticus
2017 - Vol. 4 p.57-75
Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
Tsuyoshi SadakiyoSadakiyo
2022 - Vol. 9 p.23-23
Erratum: Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
Vinay K Sharma
2016 - Vol. 3 p.9-12
Single dose oral toxicity study of Picrorhiza kurroa rhizome extract in Wistar rats
Wasoontarajaroen Siriwat
2024 - Vol. 11 p.27-35
Development of an in vivo pain assessment method for exposure to intermediate-frequency magnetic fields
Yan Sai
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
Yasue Sakaguchi
2019 - Vol. 6 p.367-382
Safety evaluation of chicken breast meat extract in chromosomal aberration study, reverse mutation test, and 90-day repeated dose study in rats
Yasuhiro Shinkai
2015 - Vol. 2 p.171-175
Health survey of workers in a 2,4,6-trinitrotoluene explosives factory in Fuxin, China
Yasuhito Shimada
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Yasuyuki Sakai
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Yifan Sun
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Yingbiao Sun
2015 - Vol. 2 p.137-145
Effects of cisplatin on testicular enzymes and Sertoli cell function in rats
Yo Shinoda
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
2020 - Vol. 7 p.77-83
Arsenite inhibits gene expression of perlecan, syndecan-1, -2, -3 and biglycan in cultured vascular endothelial cells
Yoshiaki Saito
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
2017 - Vol. 4 p.109-119
Permeability of skin to silver nanoparticles after epidermal skin barrier disruption in rats
Yoshihisa Suzuki
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Yoshimasa Sugiura
2018 - Vol. 5 p.171-179
Effects of fish oil-enriched Sasa-kamaboko diet in decreasing hepatic lipid levels in a mouse fatty liver disease model
Yoshimi Shimizu
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
Yoshiyuki Shigeta
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
2021 - Vol. 8 p.103-116
Repeated-dose and reproductive/developmental toxicity screening of polyoxymethylene in rats
Yu F. Sasaki
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Yuhki Sato
2023 - Vol. 10 p.325-333
Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Yuka Sakaguchi
2017 - Vol. 4 p.285-293
General toxicity of a vitamin K1 2,3-epoxide reductase (VKOR) inhibitor, 3-acetyl-5-methyltetronic acid, in rats
Yukari Sato
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Yukari Shigemoto-Mogami
2014 - Vol. 1 p.87-94
Residual metals in carbon nanotubes suppress the proliferation of neural stem cells
Yukihisa Suzuki
2024 - Vol. 11 p.27-35
Development of an in vivo pain assessment method for exposure to intermediate-frequency magnetic fields
Yukina Syakushi
2015 - Vol. 2 p.239-243
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
Yukino Segawa
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
Yuko Sakaguchi
2022 - Vol. 9 p.145-150
The effects on growth and reproductive function by parabens in C. elegans
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
Yuko Sekino
2014 - Vol. 1 p.87-94
Residual metals in carbon nanotubes suppress the proliferation of neural stem cells
Yuko Shimamura
2019 - Vol. 6 p.9-14
Investigation of DNA damage of glycidol and glycidol fatty acid esters using Fpg-modified comet assay
2018 - Vol. 5 p.63-69
Assessment of bladder DNA damage due to 2-acetylaminofluorene, diuron, and terephthalic acid by the rat comet assay
Yuriko Sakamaki
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Yusuke Shibui
2014 - Vol. 1 p.29-38
28-Day dietary toxicity study of L-phenylalanine in rats
Yusuke Shinkai
2021 - Vol. 8 p.1-6
Comprehensive analysis of the alteration of plasma miRNA expression level in mice exposed to diesel exhaust
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
Yusuke Suzuki
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
2017 - Vol. 4 p.9-14
Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs

T

Aiko Takasu
2017 - Vol. 4 p.241-245
In vitro genotoxicity test package of antibiotics for human use submitted to the Japanese regulatory agency during 2004–2015
Akane Takahashi
2018 - Vol. 5 p.181-184
A zinc complex that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells
Aki Terada
2021 - Vol. 8 p.189-193
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity
Akiko Takaoka
2023 - Vol. 10 p.113-123
A trial to predict skin irritancy of cosmetic products using cytotoxicity tests
Akinori Takemura
2019 - Vol. 6 p.281-286
Transmission electron microscopy of the benzbromaroneinduced change in mitochondrial morphology in HepG2 cells
Atsushi Tabata
2018 - Vol. 5 p.99-103
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells
Atsuya Takagi
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
Chiharu Tohyama
2017 - Vol. 4 p.269-273
Effect of metallothionein on ethanol-induced hepatotoxicity in mice
Chise Tateno
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Cristiane Okuda Torello
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Edite Taninaga
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Eiko Takahashi
2016 - Vol. 3 p.177-183
Estimation of occupational exposure to drugs during tablet crushing
Erika Tachihara
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
Fumiya Tokito
2024 - Vol. 11 p.17-25
Comparative analysis of bile canaliculi formation in fresh and flask-delivered human hepatocytes from humanized mouse livers under sufficient oxygen supply
Haruna Tahara
2023 - Vol. 10 p.295-300
Derivation of permitted daily exposure value for 1,8-diazabicyclo[5.4.0]undec-7-ene in pharmaceutical products
2023 - Vol. 10 p.105-112
A survey of on the use of genotoxicity and carcinogenicity testing packages for ophthalmic drug development
Hideyo Takahashi
2023 - Vol. 10 p.189-197
An application of the magnetometer detection system to Crl:CD1 (ICR) mice for head twitch response induced by hallucinogenic 5-HT2A agonists
Hiroki Taguchi
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Hiroki Tomisawa
2019 - Vol. 6 p.249-252
Localization of the trichloroethylene-related compound S-(1, 2-dichlorovinyl)-L-cysteine in mouse cartilage
Hiromasa Takashima
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
Hiromitsu Tsuzuki
2016 - Vol. 3 p.121-125
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes
Hiroshi Takehara
2016 - Vol. 3 p.1-8
Physiological conditions in iPRECIO® -implanted rats
Hiroyuki Taguchi
2020 - Vol. 7 p.281-286
Influence of skin condition on the skin penetration of dextran 4000 and ovalbumin
Hiroyuki Takahashi
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023
Hiroyuki Tsuda
2023 - Vol. 10 p.137-141
mRNA expression levels of CCL4, IL6, and CXCL2 in multiwalled carbon nanotube induced lung tumors in rats
2023 - Vol. 10 p.27-30
mRNA expression profile of cytokines in rat primary alveolar macrophages treated with multiwalled carbon nanotube (MWCNT)
Hitomi Takanobu
2015 - Vol. 2 p.201-208
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient
Ikuko Taira
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
Ikumi Tamura
2015 - Vol. 2 p.201-208
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient
Jintana Tragulpakseerojn
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Jun Takahashi
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Jun-ichi Takeshita
2014 - Vol. 1 p.1-6
Investigation of organ-specific assessment factors related to sub-acute and sub-chronic toxicity studies
Kaoru Tachiyashiki
2014 - Vol. 1 p.115-121
Diallyl disulfide administration increases the number of B-lymphocytes in the rat spleen
Kaoru Toyoda
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
Kazuaki Tanaka
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
Kazuhiko Takamatsu
2016 - Vol. 3 p.19-25
A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Kazumi Takashima
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Kazuya Tabata
2020 - Vol. 7 p.105-114
Evaluation of cytokine storms in a disseminated intravascular coagulation monkey model
Kazuya Takeuchi
2022 - Vol. 9 p.163-166
Comet assay of thyroid gland in rats treated with ethyl methanesulfonate
Ken Tachibana
2021 - Vol. 8 p.1-6
Comprehensive analysis of the alteration of plasma miRNA expression level in mice exposed to diesel exhaust
2019 - Vol. 6 p.57-63
Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities
Ken Takeda
2021 - Vol. 8 p.1-6
Comprehensive analysis of the alteration of plasma miRNA expression level in mice exposed to diesel exhaust
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Kenji Tokuda
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Kenjiro Tatematsu
2022 - Vol. 9 p.7-16
Dietary rapeseed (canola) oil suppresses testosterone production and increases plasma aldosterone level in stroke-prone spontaneously hypertensive rats (SHRSP)
Kenjiro Tsubota
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
Kento Tanaka
2022 - Vol. 9 p.25-30
Erratum: Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
2017 - Vol. 4 p.121-126
Utility of murine dendritic cell line DC2.4 for in vitro assay of skin-sensitization potential
Koichi Takeya
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
Koretaro Takahashi
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Maho Tanaka
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Mai Todoroki
2020 - Vol. 7 p.97-103
5-Fluorocytosine induces fetal skeletal malformations in rats by altering expression of Homeobox genes
Maki Tokumoto
2023 - Vol. 10 p.133-136
Effect of cadmium on expression of BIRC family genes in HeLa cells
2018 - Vol. 5 p.93-97
Effect of heat shock protein gene expression on cadmium toxicity in human proximal tubular cells
2017 - Vol. 4 p.275-278
Effect of chronic cadmium exposure on the gene expression of Birc family in the mouse kidney and liver
2017 - Vol. 4 p.269-273
Effect of metallothionein on ethanol-induced hepatotoxicity in mice
2016 - Vol. 3 p.285-289
Sensitivity of MT-III null mice upon chronic exposure to cadmium
2016 - Vol. 3 p.281-284
Cadmium-induced protein ubiquitination in UBA80 knockdown HK-2 cells
2016 - Vol. 3 p.257-280
DNA microarray analysis of fetal liver of C57BL/6J mice exposed to cadmium during gestation
2015 - Vol. 2 p.259-262
The enhancement effect of HIST1H4C knockdown on cadmium toxicity in human proximal tubular cells
2014 - Vol. 1 p.165-167
The involvement of GPRC5B in cadmium toxicity in HK-2 cells
2014 - Vol. 1 p.131-133
Effects of cadmium on the gene expression of SLC39A1 coding for ZIP1 protein
Mamoru Tanaka
2014 - Vol. 1 p.39-47
Safety evaluation of morphological changes in corneal endothelial cells induced by K-115 in cynomolgus monkeys
Marika Toma
2021 - Vol. 8 p.221-228
Influence of trans-fatty acids on non-alcoholic steatohepatitis with hepatic fibrosis induced by a choline-deficient, methionine-lowered, L-amino acid-defined diet in male Harlan Sprague Dawley rats
Mariko Tsurumoto
2023 - Vol. 10 p.69-82
A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
2023 - Vol. 10 p.59-68
A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats
Masaharu Tanaka
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
Masaki Tsuji
2022 - Vol. 9 p.17-21
A novel high-purity carbon-nanotube yarn electrode used to obtain biopotential measurements in small animals: flexible, wearable, less invasive, and gel-free operation
Masao Takano
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
Masao Tomiki
2021 - Vol. 8 p.183-187
Improvement of a fish holding device for oral administration to zebrafish
Masao Tsuchiya
2015 - Vol. 2 p.249-258
Developmental changes in associative learning behavior in male rats
2014 - Vol. 1 p.135-142
Effects of a repeated low dose of LiCl injection under conditioned taste/flavor aversion using xylene
Masaru Tsuboi
2023 - Vol. 10 p.69-82
A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
2023 - Vol. 10 p.59-68
A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats
2016 - Vol. 3 p.1-8
Physiological conditions in iPRECIO® -implanted rats
Masatoshi Takaya
2016 - Vol. 3 p.243-250
Safety assessment of probiotic bacteria, Bacillus coagulans strain SANK70258, in rats
Masayuki Takaishi
2022 - Vol. 9 p.117-122
Leaf extracts from Camellia sinensis and Argania spinosa suppress oxidative stress and chemokine release in human 3-dimensional cultured epidermis exposed to PM2.5 collected with cyclonic separation
Masayuki Tomohiro
2023 - Vol. 10 p.199-208
Investigation of the maximum feasible volume of subretinal injections into rat and cynomolgus monkey eyes
2023 - Vol. 10 p.157-167
Evaluation of maximal dosing volume for intravitreal injections in cynomolgus monkeys
Masufumi Takiguchi
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
Mayumi Tsuji
2016 - Vol. 3 p.63-65
Transcription factor activation in rat primary astrocytes exposed to methylmercury
Mayuu Tokudome
2023 - Vol. 10 p.179-187
Effect of blood collection tubes containing separation gels on the measurement of drug concentrations in clinical toxicology
Megumi Terada
2020 - Vol. 7 p.133-139
Sex differences in the effects of high-fat diet on mouse sciatic nerves
2020 - Vol. 7 p.115-121
Effects of estrogen on fatty-acid-induced cytotoxicity in mouse Neuro-2a neural cells
2018 - Vol. 5 p.63-69
Assessment of bladder DNA damage due to 2-acetylaminofluorene, diuron, and terephthalic acid by the rat comet assay
2018 - Vol. 5 p.57-62
Scanning electron microscopic analysis of the bladder epithelium in terephthalic acid administered rats: a case in acute toxicity study
Michihito Takabe
2021 - Vol. 8 p.7-16
Genotoxicity of Monascus Color Y-001
Mika Takahashi
2015 - Vol. 2 p.191-200
A repeated dose 28-day oral toxicity study of β-bromostyrene in rats
2015 - Vol. 2 p.177-190
Repeated dose and reproductive/developmental toxicity of long-chain perfluoroalkyl carboxylic acids in rats: perfluorohexadecanoic acid and perfluorotetradecanoic acid
Mikako Terashima-Hasegawa
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Miki Tokuyasu
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Mina Takamatsu
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Misuzu Tanaka
2021 - Vol. 8 p.23-31
The influence of long-term ingestion of D-allulose in hypercholesterolemia patients under statin therapy
2020 - Vol. 7 p.15-31
Safety and efficacy of a 48-week long-term ingestion of D-allulose in subjects with high LDL cholesterol levels
2019 - Vol. 6 p.225-234
Safety evaluation of 12-week continuous ingestion of D-allulose in borderline diabetes and type 2 diabetes
Mitsuru Tanaka
2020 - Vol. 7 p.123-132
In vitro toxicity studies of epoxyoleic acid and diepoxylinoleic acid
Mitsutoshi Takaya
2014 - Vol. 1 p.135-142
Effects of a repeated low dose of LiCl injection under conditioned taste/flavor aversion using xylene
Motoki Takagi
2016 - Vol. 3 p.47-53
Differing responses of human stem cell-derived cardiomyocytes to arrhythmogenic drugs, determined using impedance measurements
Musubu Takahashi
2018 - Vol. 5 p.181-184
A zinc complex that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells
Naho Tsuji
2022 - Vol. 9 p.163-166
Comet assay of thyroid gland in rats treated with ethyl methanesulfonate
Nobuaki Tominaga
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
2021 - Vol. 8 p.189-193
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Norihisa Tatarazako
2015 - Vol. 2 p.201-208
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient
Qian Tang
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Reika Takada
2022 - Vol. 9 p.187-196
Pharmaceutical concentrations and antimicrobial activity using hypersusceptible Escherichia coli lacking TolC component of multidrug efflux system in the Ayase River in Japan
Rose C. G. Trevisane
2023 - Vol. 10 p.45-58
Chlorella modulation of gut microbiota dysbiosis in patients with type-2 diabetes
2023 - Vol. 10 p.31-44
Chlorella improves inflammatory profiles and quality of life of prediabetes and diabetes patients
Ryosuke Tanino
2022 - Vol. 9 p.197-202
Transient increase in plasma urate induced by a single oral dose of fructose in rats
Sarah Tominaga
2019 - Vol. 6 p.25-29
Protective effect of the Kampo formula “Juzen-taiho-to” on isoniazid- and rifampicin-induced hepatotoxicity in mice
Satoshi Tamai
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Satoshi Tsuji
2020 - Vol. 7 p.85-96
Utility of measuring long bone length in toxicity studies: results of a 14-day repeated dose oral toxicity study of dexamethasone in young, periadolescent and adult rats
Sawa Tanaka
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Seiko Tamano
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
Setsuko Tabata
2021 - Vol. 8 p.33-36
A survey on the cadmium contamination in brown rice sold in Tokyo
Shihori Tanabe
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
2017 - Vol. 4 p.247-259
Toxicity of repeated 28-day oral administration of acenaphthylene in rats
2017 - Vol. 4 p.207-218
Toxicity in repeated 28-day oral administration of N-phenyl-1-naphthylamine in rats
Shiro Toyohisa
2021 - Vol. 8 p.183-187
Improvement of a fish holding device for oral administration to zebrafish
Sho Tanaka
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Shuhei Tanaka
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Shuji Tsuda
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
2015 - Vol. 2 p.201-208
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient
Shuji Tsuruoka
2022 - Vol. 9 p.17-21
A novel high-purity carbon-nanotube yarn electrode used to obtain biopotential measurements in small animals: flexible, wearable, less invasive, and gel-free operation
Shuso Takeda
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
2017 - Vol. 4 p.101-103
Phytocannabinoids, Δ9-tetrahydrocannabinol and cannabidiol, as human calpain-1 (CAPN1) activators
2016 - Vol. 3 p.115-119
Possible involvement of FosB in (–)-xanthatin-mediated anti-proliferative effects in human cancer MDA-MB-231 cells
2016 - Vol. 3 p.55-61
HU-210, a synthetic analog of Δ9-THC, is not a modifier of estrogen signaling in MCF-7 human breast cancer cells
2016 - Vol. 3 p.33-37
Fipronil, an insecticide, acts as an anti-estrogen via the concomitant down-regulation of ERα and PES1
2015 - Vol. 2 p.233-238
(–)-Xanthatin-mediated marked up-regulation of RhoB, a sensor for damaged DNA
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Soraaki Takahashi
2015 - Vol. 2 p.83-87
Measurement of oral bacterial counts in dogs by dielectrophoretic impedance
Suzuka Tamaki
2017 - Vol. 4 p.179-186
Disposition of perfluorododecanoic acid in male rats after oral administration
Tadakazu Takahashi
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
Takao Tanaka
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
2017 - Vol. 4 p.279-284
Hepatic glucose-dependent insulinotropic polypeptide expression is modified by supplementing high-dose thiamine in obese diabetic rats
2015 - Vol. 2 p.55-60
Metabolic fate of excessive glucose in fibroblast cells in a diabetic setting
Takao Tobe
2014 - Vol. 1 p.73-79
Effects of organic and inorganic mercury(II) on gene expression via DNA conformational changes
Takashi Toyama
2019 - Vol. 6 p.167-170
Methylmercury causes neuronal cell death via M1-microglial activation in organotypic slices prepared from mouse cerebral cortex
2017 - Vol. 4 p.41-43
Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells
2015 - Vol. 2 p.229-231
Citrulline enhances methylmercury toxicity in HEK293 and C17.2 cells
2015 - Vol. 2 p.227-228
Metabolomic analysis of low molecular weight substances released into medium from HEK293 cells treated with methylmercury
2015 - Vol. 2 p.223-226
Methylmercury induces release of a cytotoxic factor from HEK293 cells into medium
Takuya Takemoto
2016 - Vol. 3 p.63-65
Transcription factor activation in rat primary astrocytes exposed to methylmercury
Tatsuya Takizawa
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Tomomi Takahashi
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Tomoyasu Toyoizumi
2022 - Vol. 9 p.173-178
Assessment of genotoxicity of 2-[2-(acetylamino)-4-[bis(2-hydroxyethyl)amino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-6) in zebrafish (Danio rerio) using the comet assay and micronucleus test
Toshio Tanaka
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Toyohisa Tsukamoto
2016 - Vol. 3 p.177-183
Estimation of occupational exposure to drugs during tablet crushing
Tsutomu Takahashi
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
2020 - Vol. 7 p.77-83
Arsenite inhibits gene expression of perlecan, syndecan-1, -2, -3 and biglycan in cultured vascular endothelial cells
2018 - Vol. 5 p.71-73
Putrescine selectively alleviates methylmercury toxicity in C17.2 mouse neural stem cells
2017 - Vol. 4 p.41-43
Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells
2017 - Vol. 4 p.37-39
Identification of transcription factors activated by methylmercury in mouse brain
2015 - Vol. 2 p.245-247
Knockdown of Acyl-CoA thioesterase 9 gene expression by siRNA confers resistance to arsenite in HEK293 cells
2015 - Vol. 2 p.239-243
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
2014 - Vol. 1 p.161-164
CDC23 knockdown reinforces methylmercury sensitivity in HEK293 cells
2014 - Vol. 1 p.113-114
Identification of growth-dependent genes involved in paraquat toxicity in Saccharomyces cerevisiae
2014 - Vol. 1 p.109-111
Overexpression of RPN8, SKP1, MIA40 or MES1 increases resistance to cadmium in Saccharomyces cerevisiae
2014 - Vol. 1 p.95-99
A screening method for growth-dependent genes involved in the cytotoxicity of chemicals in Saccharomyces cerevisiae
Wataru Takasaki
2015 - Vol. 2 p.25-36
Impact of different blood sampling techniques on plasma biomarkers for skeletal myopathy in conscious rats
Xiaoyan Tan
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Xuechen Tian
2018 - Vol. 5 p.123-126
The impact on the activity of acetylcholinesterase of a polylysine-ApoE peptide carrier targeting the blood brain barrier
Yasuaki Tamura
2015 - Vol. 2 p.209-216
Zn2+-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-n-octyl-4-isothiazolin-3-one in rat thymocytes
Yasunari Takami
2022 - Vol. 9 p.179-186
Role of cytoplasmic acetyltransferases, NAA60 and HAT1, in cellular protection against genotoxic agents
Yasunori Takahashi
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Yasuo Tsutsumi
2017 - Vol. 4 p.109-119
Permeability of skin to silver nanoparticles after epidermal skin barrier disruption in rats
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Yayoi Tsuneoka
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
2020 - Vol. 7 p.77-83
Arsenite inhibits gene expression of perlecan, syndecan-1, -2, -3 and biglycan in cultured vascular endothelial cells
Yoshitaka Tanetani
2020 - Vol. 7 p.133-139
Sex differences in the effects of high-fat diet on mouse sciatic nerves
Yoshitaka Tayama
2016 - Vol. 3 p.177-183
Estimation of occupational exposure to drugs during tablet crushing
Yoshiyuki Tazura
2017 - Vol. 4 p.15-21
Normal ovarian aging, but modified T-cell differentiation, in female mice following neonatal exposure to bisphenol A
Yu Takahashi
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
Yu Tan
2019 - Vol. 6 p.15-23
Supplementation with lower doses of EGCg reduces liver injury markers of type 2 diabetic rats
Yu-ki Tanaka
2019 - Vol. 6 p.181-185
Species difference in antimony and arsenic metabolism between hamster and rat after administration of tri- or pentavalent inorganic antimony
Yuhji Taquahashi
2023 - Vol. 10 p.69-82
A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
2023 - Vol. 10 p.59-68
A 90-day dose toxicity study of 2-(2H-benzotriazol-2-yl)-6-dodecyl-4-methylphenol in rats
2022 - Vol. 9 p.17-21
A novel high-purity carbon-nanotube yarn electrode used to obtain biopotential measurements in small animals: flexible, wearable, less invasive, and gel-free operation
2021 - Vol. 8 p.169-175
Development of an inhalation exposure system of a pressurized metered-dose inhaler (pMDI) formulation for small experimental animals
Yuichiro Taira
2019 - Vol. 6 p.37-44
Acute hepatotoxicity and drug/chemical interaction toxicity of 10-nm silver nanoparticles in mice
Yuka Takagi
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
Yuka Takezoe
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
Yukihiko Takagi
2021 - Vol. 8 p.49-52
Acrylamide in dog food
2019 - Vol. 6 p.75-79
Age-dependent aggravation of oral malodor and periodontal disease in dogs
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
Yukimi Takemoto
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Yuko Togashi
2022 - Vol. 9 p.103-110
Fecal microRNA223 as an indicator of recovery in chronic DSS colitis model in rats
2021 - Vol. 8 p.177-182
Expression of miRNAs in the colon, rectum, plasma, and feces in rats with dextran sulfate sodium
Yushang Tang
2019 - Vol. 6 p.207-215
Procyanidin protects HK-2 cells against cisplatin-induced injury through antioxidant action involving Nrf2/HO-1 signaling pathway
Yushiro Tanaka
2018 - Vol. 5 p.75-82
Male-specific prolongation of prothombin time by industrial chemicals

U

Akira Unami
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
2016 - Vol. 3 p.39-46
Toxicogenomic prediction with graph-based structured regularization on transcription factor network
2015 - Vol. 2 p.161-170
Toxicogenomic prediction with group sparse regularization based on transcription factor network information
Akira Ushiyama
2024 - Vol. 11 p.27-35
Development of an in vivo pain assessment method for exposure to intermediate-frequency magnetic fields
Chie Ushio
2020 - Vol. 7 p.141-152
Maltosyltrehalose Syrup: Bacterial reverse mutation test, and 90-day feeding and 90-day repeated oral dose toxicity studies in rats
2019 - Vol. 6 p.299-317
Glucosyl hesperidin: safety studies
Gantulga Uuganbaatar
2016 - Vol. 3 p.121-125
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes
Hajime Uchida
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Hiroki Uchida
2016 - Vol. 3 p.67-74
Prenatal exposure to rutile-type alumina-coated titanium dioxide nanoparticles impairs mouse spermatogenesis
Hisashi Uchiyama
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Junpei Ueda
2019 - Vol. 6 p.1-8
Thiamine supplementation modulates oxidative stress by inhibiting hepatic adenosine diphosphate (ADP)-ribosylation in obese diabetic rats
Kazuo Ushida
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
2022 - Vol. 9 p.123-133
Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
Kinuko Uno
2021 - Vol. 8 p.221-228
Influence of trans-fatty acids on non-alcoholic steatohepatitis with hepatic fibrosis induced by a choline-deficient, methionine-lowered, L-amino acid-defined diet in male Harlan Sprague Dawley rats
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
Kohei Uchino
2019 - Vol. 6 p.9-14
Investigation of DNA damage of glycidol and glycidol fatty acid esters using Fpg-modified comet assay
Koji Ueda
2020 - Vol. 7 p.171-176
The aminoethyl group is a crucial structural moiety in metal-mediated oxidative DNA damage by catecholamines
2014 - Vol. 1 p.73-79
Effects of organic and inorganic mercury(II) on gene expression via DNA conformational changes
Makoto Usami
2021 - Vol. 8 p.205-213
Potency shift in immunomodulatory activities of zinc oxide (ZnO) nanoparticles in THP-1 cells is associated with cytotoxicity
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
2020 - Vol. 7 p.249-252
In vitro cytotoxicity of the thyrotoxic and hepatotoxic rubber antioxidant 2-mercaptobenzimidazole and its 4- or 5-methyl derivatives in rabbit corneal cells
2018 - Vol. 5 p.113-116
In vitro metabolism of 4-methyl- and 5-methyl-2-mercaptobenzimidazole, thyrotoxic and hepatotoxic rubber antioxidants, in rat liver microsomes
2017 - Vol. 4 p.31-35
Proteomic analysis of valproic acid-induced embryotoxicity in cultured post-implantation rat embryos
Masahiro Uto
2016 - Vol. 3 p.89-99
Requirements for human iPS cell-derived hepatocytes as an alternative to primary human hepatocytes for assessing absorption, distribution, metabolism, excretion and toxicity of pharmaceuticals
Masashi Uchida
2017 - Vol. 4 p.285-293
General toxicity of a vitamin K1 2,3-epoxide reductase (VKOR) inhibitor, 3-acetyl-5-methyltetronic acid, in rats
Masaya Uchida
2022 - Vol. 9 p.95-102
Multigenerational effects of neonicotinoids (acetamiprid, clothianidin) on growth, fertility and motility of nematode C. elegans
2021 - Vol. 8 p.189-193
Electroporation of thalidomide to medaka (Oryzias latipes) embryo for evaluation of developmental toxicity
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Miki Uchiyama
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
Naohisa Umeya
2024 - Vol. 11 p.57-67
Effects of food restriction for 3 or 7 days on toxicity-related parameters in rats
Naoto Uramaru
2023 - Vol. 10 p.265-277
Differential expression of Cytochrome P450 1A2 in simple fatty liver and steatohepatitis
2018 - Vol. 5 p.185-193
Study of metabolic activation of the UV-filter octyl methoxycinnamate for endocrine-disrupting activity
Noriko Umemoto
2016 - Vol. 3 p.79-87
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs
Noriko Usui
2019 - Vol. 6 p.333-340
Assessment of the acute toxicity of 16 veterinary drugs and a disinfectant to aquatic and soil organisms
Rumiko Usu
2017 - Vol. 4 p.191-193
A new insight into proliferative action of bisphenol A at low-dose
2017 - Vol. 4 p.187-189
HSP70-Ran-RCC1 transport system during cadmium-induced apoptosis in porcine kidney LLC-PK1 cells
2017 - Vol. 4 p.159-165
Distinct regulation of nuclear localization of caspase-activated DNase during cadmium-induced apoptosis of the target cells
2017 - Vol. 4 p.151-158
Orally administered p-nitrotoluene causes hyperactivity, concomitant with gliosis and impairment of tyrosine hydroxylase immunoreactivity in the rat substantia nigra
Ryo Uzuki
2021 - Vol. 8 p.1-6
Comprehensive analysis of the alteration of plasma miRNA expression level in mice exposed to diesel exhaust
Shimpei Ushio
2022 - Vol. 9 p.23-23
Erratum: Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
2019 - Vol. 6 p.341-357
Safety assessment of isomaltodextrin-producing enzymes from Paenibacillus alginolyticus
2017 - Vol. 4 p.57-75
Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
Sugi Ueno
2014 - Vol. 1 p.151-159
Safety evaluation of mutagenecity, acute and subacute toxicity study of Chlorella vulgaris CK-22 in rats
Tadayoshi Ueda
2015 - Vol. 2 p.41-48
Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Takaaki Umano
2022 - Vol. 9 p.31-36
Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
Takamitsu Unoki
2020 - Vol. 7 p.161-166
Combined exposure to environmental electrophiles enhances cytotoxicity and consumption of persulfide
Takuya Uchikawa
2018 - Vol. 5 p.117-122
Chlorella supplementation decreases methylmercury concentrations of hair and blood in healthy volunteers
2014 - Vol. 1 p.151-159
Safety evaluation of mutagenecity, acute and subacute toxicity study of Chlorella vulgaris CK-22 in rats
Tohru Uesugi
2022 - Vol. 9 p.71-83
Genotoxicity and subchronic toxicity of a kaempferol aglycone-rich product produced from horseradish leaves
Tomonobu Umeda
2021 - Vol. 8 p.249-260
Low-dose ionizing radiation suppresses the apoptosis-induced by serum-removal culture
Tomoyuki Ueda
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Toru Usui
2024 - Vol. 11 p.57-67
Effects of food restriction for 3 or 7 days on toxicity-related parameters in rats
Yoshihide Ueda
2016 - Vol. 3 p.1-8
Physiological conditions in iPRECIO® -implanted rats
Yumiko Uchiyama
2019 - Vol. 6 p.15-23
Supplementation with lower doses of EGCg reduces liver injury markers of type 2 diabetic rats

V

Pham Hung Viet
2021 - Vol. 8 p.117-122
Health risk assessment on mercury, cadmium and lead in marketed cigarettes

W

Ai-Ping Wang
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Akihito Watanabe
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
Ashley Walker
2019 - Vol. 6 p.45-56
Cytotoxic effects of parathion, paraoxon, and their methylated derivatives on a mouse neuroblastoma cell line NB41A3
Atsushi Watanabe
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
2019 - Vol. 6 p.253-258
Impact of dietary calcium and phosphorus levels on an ovariectomized Sprague-Dawley rat model of osteoporosis
Bambang Wispriyono
2020 - Vol. 7 p.215-225
The dietary intake of mercury from rice and human health risk in artisanal small-scale gold mining area, Indonesia
Chao Wang
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
Chiho Watanabe
2016 - Vol. 3 p.185-193
Neurobehavioral toxicity related to the exposure of weaning mice to low-level mercury vapor and methylmercury and influence of aging
Chin Piow Wong
2023 - Vol. 10 p.143-156
Safety studies of LAURESH® a standardized Laurus nobilis leaf extract
Dong-pan Wu
2020 - Vol. 7 p.77-83
Arsenite inhibits gene expression of perlecan, syndecan-1, -2, -3 and biglycan in cultured vascular endothelial cells
Eiji Wato
2014 - Vol. 1 p.39-47
Safety evaluation of morphological changes in corneal endothelial cells induced by K-115 in cynomolgus monkeys
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Fumiko Watanabe
2019 - Vol. 6 p.65-74
Twenty-eight-day oral toxicity study of L-hydroxyproline in rats with 14-day post-treatment observation period
Haibin Wei
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Hairuo Wen
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Haruna Watanabe
2015 - Vol. 2 p.201-208
Bioconcentration of perfluorinated compounds in wild medaka is related to octanol/water partition coefficient
Hikaru Watanabe
2022 - Vol. 9 p.23-23
Erratum: Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
2019 - Vol. 6 p.341-357
Safety assessment of isomaltodextrin-producing enzymes from Paenibacillus alginolyticus
2017 - Vol. 4 p.57-75
Safety assessment of a soluble dietary fiber, isomaltodextrin, enzymatically produced from starch
Jin-Feng Wei
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Jing Wu
2020 - Vol. 7 p.207-214
Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests
Kazuhito Watanabe
2017 - Vol. 4 p.195-200
Expression levels of 39 Cyp mRNAs in the mouse brain and neuroblastoma cell lines, C-1300N18 and NB2a – strong expression of Cyp1b1
2017 - Vol. 4 p.101-103
Phytocannabinoids, Δ9-tetrahydrocannabinol and cannabidiol, as human calpain-1 (CAPN1) activators
2016 - Vol. 3 p.55-61
HU-210, a synthetic analog of Δ9-THC, is not a modifier of estrogen signaling in MCF-7 human breast cancer cells
Keiji Wada
2024 - Vol. 11 p.27-35
Development of an in vivo pain assessment method for exposure to intermediate-frequency magnetic fields
Kenichiro Watanabe
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Kiyoshi Wako
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Koji Watanabe
2014 - Vol. 1 p.151-159
Safety evaluation of mutagenecity, acute and subacute toxicity study of Chlorella vulgaris CK-22 in rats
Kouki Watanabe
2017 - Vol. 4 p.229-239
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Michael F. Wempe
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
Michael F. Wempe
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023
Rui-Sheng Wang
2018 - Vol. 5 p.153-159
In utero exposure to 2,2’,4,4’,5,5’-hexachlorobiphenyl accelerates the onset of eye opening in rat offspring
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Ryuichi Watanabe
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Shayla Williams
2019 - Vol. 6 p.45-56
Cytotoxic effects of parathion, paraoxon, and their methylated derivatives on a mouse neuroblastoma cell line NB41A3
Sheng-Yang Wang
2016 - Vol. 3 p.205-216
In vitro and in vivo toxicological assessments of Antrodia cinnamomea health food product (Leader Antrodia cinnamomea Capsule)
Shin Wakui
2023 - Vol. 10 p.1-1
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] The Original Article was published on May 13, 2017
2017 - Vol. 4 p.85-93
Retraction: Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposure
[Notice] Editor's Announcement was published on June 6, 2023
Takashi Washio
2016 - Vol. 3 p.39-46
Toxicogenomic prediction with graph-based structured regularization on transcription factor network
2015 - Vol. 2 p.161-170
Toxicogenomic prediction with group sparse regularization based on transcription factor network information
Wataru Watanabe
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Xin Wang
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Xue Wang
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Yanjiao Wang
2017 - Vol. 4 p.41-43
Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells
Ying Wang
2016 - Vol. 3 p.157-166
A high-throughput Bhas 42 cell transformation assay for the determination of the carcinogenicity of three herbal extracts
Yoko Watanabe
2019 - Vol. 6 p.57-63
Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities
2018 - Vol. 5 p.185-193
Study of metabolic activation of the UV-filter octyl methoxycinnamate for endocrine-disrupting activity
Yuko Watanabe
2016 - Vol. 3 p.243-250
Safety assessment of probiotic bacteria, Bacillus coagulans strain SANK70258, in rats
Yumi Wako
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Yunbiao Wang
2019 - Vol. 6 p.45-56
Cytotoxic effects of parathion, paraoxon, and their methylated derivatives on a mouse neuroblastoma cell line NB41A3

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Ao Yi Xiang
2020 - Vol. 7 p.1-7
Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Jiegou Xu
2023 - Vol. 10 p.137-141
mRNA expression levels of CCL4, IL6, and CXCL2 in multiwalled carbon nanotube induced lung tumors in rats
2023 - Vol. 10 p.27-30
mRNA expression profile of cytokines in rat primary alveolar macrophages treated with multiwalled carbon nanotube (MWCNT)
Rafael Matos Ximenes
2014 - Vol. 1 p.7-13
Edematogenic and myotoxic activities induced by snake venom of Philodryas nattereri from the Northeast of Brazil
Wang Xiao-dan
2015 - Vol. 2 p.9-17
Effects of sub-chronic exposure to deltamethrin on shuttle-box avoidance and contents of amino acid neurotransmitters in hippocampus of mice

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Akari Yoshimura
2017 - Vol. 4 p.1-7
Simultaneous depletion of WRNIP1 and RAD52 restores resistance to oxidative stress
Akihito Yokosuka
2014 - Vol. 1 p.169-172
Estimation of endoplasmic reticulum stress-inducing ability of nobiletin, a citrus polymethoxyflavonoid, in SK-N-SH human neuroblastoma cells
Akinori Yasuda
2014 - Vol. 1 p.135-142
Effects of a repeated low dose of LiCl injection under conditioned taste/flavor aversion using xylene
Akira Yamauchi
2020 - Vol. 7 p.201-206
Retinoic acid dramatically enhances cytotoxicity of equol against human monoblastic U937 cells, but not against human peripheral neutrophils
Akira Yasutake
2018 - Vol. 5 p.117-122
Chlorella supplementation decreases methylmercury concentrations of hair and blood in healthy volunteers
Asami Yamamoto
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Ayumi Yamamoto
2016 - Vol. 3 p.143-150
Peroxisome proliferator activated receptor-mediated genotoxicity of perfluoroalkyl acids using human lymphoblastoid cells
Chika Yamamoto
2020 - Vol. 7 p.233-239
Nucleolin positively regulates spontaneous cell proliferation but is not involved in inhibition of proliferation by lead in cultured bovine aortic endothelial cells
2018 - Vol. 5 p.181-184
A zinc complex that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
Dai Yamamoto
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
David T. Yeung
2016 - Vol. 3 p.195-204
Acute toxicity of phorate oxon by oral gavage in the Sprague-Dawley rat
Eiko Yoshida
2022 - Vol. 9 p.1-5
Glyceraldehyde 3-phosphate dehydrogenase converts methylmercury to its sulfur adduct with lowered toxicity through sulfane sulfur atoms on Cys247
2018 - Vol. 5 p.181-184
A zinc complex that suppresses the expression of a reactive sulfur species-producing enzyme, cystathionine γ-lyase, in cultured vascular endothelial cells
2016 - Vol. 3 p.109-113
Cytotoxicity of zinc, copper and rhodium complexes with 1,10-phenanthroline or 2,9-dimethyl-1,10-phenanthroline in cultured vascular endothelial cells
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
Feng Ye
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
Feng Yong-quan
2015 - Vol. 2 p.9-17
Effects of sub-chronic exposure to deltamethrin on shuttle-box avoidance and contents of amino acid neurotransmitters in hippocampus of mice
Haruna Yabe
2017 - Vol. 4 p.1-7
Simultaneous depletion of WRNIP1 and RAD52 restores resistance to oxidative stress
Hideaki Yokoyama
2017 - Vol. 4 p.9-14
Effects of oral administration of gelatin capsules on plasma insulin and glucagon levels in dogs
Hideki Yasui
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Hiroki Yoshida
2021 - Vol. 8 p.215-220
Effects of intranasal administration of multi-walled carbon nanotube (MWCNT) suspension on respiratory syncytial virus (RSV) infection in mice
Hiroki Yoshioka
2019 - Vol. 6 p.113-116
Impairment of fertilization efficiency in mice following nano-sized titanium exposure
2019 - Vol. 6 p.25-29
Protective effect of the Kampo formula “Juzen-taiho-to” on isoniazid- and rifampicin-induced hepatotoxicity in mice
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
2018 - Vol. 5 p.105-112
The Kampo formula “Juzen-taiho-to” exerts protective effects on ethanol-induced liver injury in mice
2017 - Vol. 4 p.261-268
Suppressive effect of Sasa veitchii extract on obesity induced by a high-fat diet through modulation of adipose differentiation in mice
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
2016 - Vol. 3 p.233-236
Hepatoprotective effect of kampo formula “Juzen-taiho-to” on bromobenzene-induced toxicity in mice
2016 - Vol. 3 p.151-156
Zinc sulfate pretreatment prevents carbon tetrachloride-induced lethal toxicity through metallothionein-mediated suppression of lipid peroxidation in mice
Hiroshi Yamamoto
2021 - Vol. 8 p.195-204
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals
Hiroshi Yokozaki
2022 - Vol. 9 p.37-46
Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
Hisaaki Yanai
2022 - Vol. 9 p.135-144
Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes
Jinwei Yang
2023 - Vol. 10 p.143-156
Safety studies of LAURESH® a standardized Laurus nobilis leaf extract
Jun-ichi Yamagishi
2022 - Vol. 9 p.187-196
Pharmaceutical concentrations and antimicrobial activity using hypersusceptible Escherichia coli lacking TolC component of multidrug efflux system in the Ayase River in Japan
Junpei Yamamoto
2021 - Vol. 8 p.49-52
Acrylamide in dog food
Kaito Yamashiro
2021 - Vol. 8 p.147-155
Relationship between renal dysfunction and change in serum electrolyte levels in patients administered with liposomal amphotericin B
Kaoru Yabe
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
Kazutaka Yoshida
2015 - Vol. 2 p.89-94
DNA microarray analysis of genes in highly metastatic 4T1E/M3 murine breast cancer cells following exposure to cannabidiolic acid
Kenji Yoshida
2020 - Vol. 7 p.105-114
Evaluation of cytokine storms in a disseminated intravascular coagulation monkey model
Kiyohito Yagi
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Kotaro Yamada
2023 - Vol. 10 p.249-258
Survey of toxicity study packages and designs of intravitreal drugs approved in Japan
Kouichi Yoshinari
2019 - Vol. 6 p.57-63
Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities
Kumio Yokoigawa
2016 - Vol. 3 p.121-125
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes
Kunihiko Yamashita
2016 - Vol. 3 p.27-31
Quantitative analysis of the relationship between the LLNA:DAE method results and the LLNA EC3 values highlights the connection between the elicitation and induction phases during skin sensitization
Lucia Satiko Yoshida-Yamashita
2023 - Vol. 10 p.91-103
Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
Makoto Yamanaka
2022 - Vol. 9 p.203-209
An in vitro microfluidic culture device for peripheral neurotoxicity prediction at low concentrations based on deep learning
Mari Yasui
2018 - Vol. 5 p.13-20
Increased hepatic triglyceride level induced by a glucokinase activator in mice
Masae Yoshikawa
2018 - Vol. 5 p.161-165
Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice
2017 - Vol. 4 p.261-268
Suppressive effect of Sasa veitchii extract on obesity induced by a high-fat diet through modulation of adipose differentiation in mice
Masatoshi Yuri
2017 - Vol. 4 p.77-83
Urinary proteome profile of renal papillary necrosis in experimental model rats
Megumi Yuki
2021 - Vol. 8 p.135-145
Extract of Siraitia grosvenorii (Luo Han Guo) protects against hepatic fibrosis in mice on a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet without trans fatty acids
Michiaki Yamashita
2015 - Vol. 2 p.67-78
Effect of prenatal methylmercury exposure on neurobehavioral development in male mice: comparison between methylmercury in fish and methylmercury chloride added to diets
Minoru Yoshida
2016 - Vol. 3 p.185-193
Neurobehavioral toxicity related to the exposure of weaning mice to low-level mercury vapor and methylmercury and influence of aging
Munehiro Yoshida
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Naohito Yamada
2020 - Vol. 7 p.41-54
Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
2019 - Vol. 6 p.287-297
Carbamazepine-induced liver injury using type 2 diabetes Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats as a model for human type 2 diabetes
Naoto Yamaguchi
2018 - Vol. 5 p.49-56
Abundant migration of midazolam and 1’-hydroxymidazolam into the fetal brain following midazolam administration to pregnant mice in the second trimester
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Natsuki Yamashita
2022 - Vol. 9 p.167-172
Induction of CYP3A4 mRNA by cooked food-derived carcinogenic heterocyclic aromatic amines in human HPL-A3 cells
Noriaki Yoshida
2019 - Vol. 6 p.31-36
Effects of lithium on developmental toxicity, teratogenicity and transcriptome in medaka embryos
Noriko Yamanaka
2014 - Vol. 1 p.101-108
Sex-dependent difference in the hepatic and pulmonary toxicological effects in mice administrated 7-chlorinated benz[a]anthracene
Noritaka Yamaguchi
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Rei Yamana
2020 - Vol. 7 p.287-289
Inhibitory effects of L-NAME, a nitric oxide synthase inhibitor, on decidual cell proliferation in mid-to-late pregnant rats
Rina Yamane
2020 - Vol. 7 p.227-232
Four-week repeated dose oral toxicity study of gum ghatti in rats
Ryo C. Yanagita
2021 - Vol. 8 p.69-73
Evaluation of the in vitro cytotoxicity of oscillatoxins E and F under nutrient-starvation culture conditions
Ryuzaburo Yuki
2014 - Vol. 1 p.143-149
Apoptotic activities of the extract from Moringa oleifera leaves on human HCT116 colon cancer cells
Satoshi Yamaori
2017 - Vol. 4 p.195-200
Expression levels of 39 Cyp mRNAs in the mouse brain and neuroblastoma cell lines, C-1300N18 and NB2a – strong expression of Cyp1b1
Shigeki Yoneyama
2014 - Vol. 1 p.39-47
Safety evaluation of morphological changes in corneal endothelial cells induced by K-115 in cynomolgus monkeys
2014 - Vol. 1 p.19-27
Nonclinical safety assessment for the sensitizing potential of K-115
Shiho Yanagisawa
2017 - Vol. 4 p.23-29
Application of a portable gas chromatograph for quantitative measurement of canine oral malodor
Shuji Yasuike
2015 - Vol. 2 p.61-66
Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells
Takako Yamada
2019 - Vol. 6 p.217-224
Recovery of increased weights of the liver and kidneys by cessation of D-allulose feeding in Wistar rats
Takashi Yamada
2021 - Vol. 8 p.195-204
Quantitative structure-activity relationship and a category approach to support algal toxicity assessment of human pharmaceuticals
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
2019 - Vol. 6 p.327-332
Development of a hepatotoxicity prediction model using in vitro assay data of key molecular events
2019 - Vol. 6 p.145-165
Comprehensive toxicity evaluation of cyclopentyl methyl ether (CPME) for establishing a permitted daily exposure level
2018 - Vol. 5 p.75-82
Male-specific prolongation of prothombin time by industrial chemicals
2018 - Vol. 5 p.1-11
A 28-day repeated oral-dose toxicity study of insecticide synergist N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2.2.2] oct-5-ene-2,3-dicarboximide in rats
2017 - Vol. 4 p.247-259
Toxicity of repeated 28-day oral administration of acenaphthylene in rats
Takashi Yamaguchi
2016 - Vol. 3 p.19-25
A study on the influence of acotiamide hydrochloride hydrate on sex hormones, using a uterotrophic bioassay in rat
2015 - Vol. 2 p.117-126
The concern for uterine carcinogenesis in safety assessments for a new pharmaceutical
Takeshi Yamazaki
2016 - Vol. 3 p.63-65
Transcription factor activation in rat primary astrocytes exposed to methylmercury
Takeshi Yasumoto
2015 - Vol. 2 p.49-54
Comparison of cytotoxicity among pectenotoxin-2 and other oxidized pectenotoxins in a rat myoblast cell line (L6) and a human rhabdomyosarcoma cell line (RD)
Takeya Yoshioka
2020 - Vol. 7 p.177-188
Repeated 28-day and 13-week dose toxicity studies of oils prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) in rats
2019 - Vol. 6 p.137-143
Genotoxicity evaluation of oil prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis)
Terumi Yamaguchi
2015 - Vol. 2 p.1-8
Effect of nanoparticles injected into larvae on spermatogenesis in the pupal testis of the sweet potato hornworm, Agrius convolvuli (L.)
Tohru Yamazaki
2015 - Vol. 2 p.127-135
Effects of dietary fish oil on cytochrome P450 3A expression in the liver of SHR/NDmcr-cp (cp/cp) rats, an animal model for metabolic syndrome
Tomohisa Yoshimura
2023 - Vol. 10 p.113-123
A trial to predict skin irritancy of cosmetic products using cytotoxicity tests
Toshinori Yoshida
2020 - Vol. 7 p.241-248
Lack of combined effect of continuous exposure to α-glycosyl isoquercitrin from fetal stages to adulthood and voluntary exercise or environmental enrichment on learning and behaviors in rats
Tsuyoshi Yamaguchi
2017 - Vol. 4 p.219-227
A 4-week oral gavage toxicity study of L-citrulline in rats
Tsuyoshi Yoshikawa
2023 - Vol. 10 p.169-178
Toxicological effects of repeated subcutaneous administration of corn oil for 4 weeks in rats
Wataru Yoshioka
2022 - Vol. 9 p.197-202
Transient increase in plasma urate induced by a single oral dose of fructose in rats
Xiao-Dan Yan
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Yasuo Yoshioka
2017 - Vol. 4 p.109-119
Permeability of skin to silver nanoparticles after epidermal skin barrier disruption in rats
2015 - Vol. 2 p.19-23
Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
Yoshikazu Yamagishi
2021 - Vol. 8 p.61-67
Effects of hemoglobin on post-mortem oxidation of bromazepam
Yoshimasa Yasuda
2015 - Vol. 2 p.101-110
Positive and negative ions by air purifier have no effects on reproductive function or postnatal growth and development in rats
Yoshinori Yamagiwa
2023 - Vol. 10 p.249-258
Survey of toxicity study packages and designs of intravitreal drugs approved in Japan
2018 - Vol. 5 p.141-147
Anatomical and histological sex differences in the eye and its accessory tissues in Dutch belted rabbits
2017 - Vol. 4 p.95-99
Repeated-dose ocular instillation toxicity study: a survey of its study design on the basis of common technical documents in Japan
2016 - Vol. 3 p.217-232
Ocular instillation toxicity study: current status and points to consider on study design and evaluation
Yoshiro Yoshizaki
2020 - Vol. 7 p.259-279
Combined repeated-dose and reproductive/developmental oral toxicity of 3-methylpentane, isooctane, and isononane in rats
Yoshitaka Yamazaki
2021 - Vol. 8 p.89-96
Inorganic polyphosphate modulates leukocyte accumulation and vascular endothelial cell permeability and ameliorates cecal ligation and puncture-induced lethality
Yukari Yamaguchi
2018 - Vol. 5 p.127-140
Carcinogenicity study of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) in F344 rats
Yukie Yanagiba
2016 - Vol. 3 p.237-242
Combined effect of circadian dysfunction and cadmium on immune suppression
2015 - Vol. 2 p.249-258
Developmental changes in associative learning behavior in male rats
2014 - Vol. 1 p.135-142
Effects of a repeated low dose of LiCl injection under conditioned taste/flavor aversion using xylene
2014 - Vol. 1 p.81-85
Hazardous effects of titanium dioxide nanoparticles on testicular function in mice
Yukiko Yanoue
2021 - Vol. 8 p.183-187
Improvement of a fish holding device for oral administration to zebrafish
Yukimasa Yamagishi
2021 - Vol. 8 p.75-80
Effects of the ethanol extract of Neopyropia yezoensis, cultivated in the Seto Inland Sea (Setonaikai), on the viability of 10 human cancer cells including endocrine therapy-resistant breast cancer cells
Yukuto Yasuhiko
2021 - Vol. 8 p.161-167
Diverse unintended on-target mutations induced by zygote genome-editing using CRISPR/Cas9 system
Yusuke Yoshioka
2024 - Vol. 11 p.37-56
Extracellular vesicle small RNAs secreted from mouse amniotic fluid induced by repeated oral administration of VPA to pregnant mice
Yutaka Yonezawa
2019 - Vol. 6 p.197-206
Multi-site study of an in vivo phototoxicity evaluation in Sprague-Dawley (SD) rats aimed at incorporating the phototoxicity assessments: effects of repeated administration and toxicokinetic blood collection on drug-induced phototoxicity
2019 - Vol. 6 p.171-179
Multi-site study of an in vivo phototoxicity evaluation in Sprague-Dawley rats: skin site and sex differences in sensitivity to drug-induced phototoxicity

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Cai Zong
2023 - Vol. 10 p.221-231
Effect of Anakinra (Kineret®) treatment on acrylamide-induced neurotoxicity in mice
Cong Zhu
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
Jiqing Zhao
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
JunXuan Zhu
2014 - Vol. 1 p.113-114
Identification of growth-dependent genes involved in paraquat toxicity in Saccharomyces cerevisiae
2014 - Vol. 1 p.109-111
Overexpression of RPN8, SKP1, MIA40 or MES1 increases resistance to cadmium in Saccharomyces cerevisiae
2014 - Vol. 1 p.95-99
A screening method for growth-dependent genes involved in the cytotoxicity of chemicals in Saccharomyces cerevisiae
Li Zhou
2016 - Vol. 3 p.127-135
Acute hepatotoxicity induced by quetiapine fumarate in larval zebrafish
Lin Zhang
2016 - Vol. 3 p.167-175
The in vivo Pig-a gene mutation assay is applied to study the genotoxicity of procarbazine hydrochloride in Sprague-Dawley rats
Piao-Piao Zhang
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Qianqian Zhang
2017 - Vol. 4 p.45-56
Oral acute and chronic toxicity studies of β, β-dimethylacrylalkannin in mice and rats
Qinya Zeng
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
Quan Zhou
2019 - Vol. 6 p.181-185
Species difference in antimony and arsenic metabolism between hamster and rat after administration of tri- or pentavalent inorganic antimony
Wanfen Zhang
2019 - Vol. 6 p.207-215
Procyanidin protects HK-2 cells against cisplatin-induced injury through antioxidant action involving Nrf2/HO-1 signaling pathway
Xuan Zhou
2018 - Vol. 5 p.123-126
The impact on the activity of acetylcholinesterase of a polylysine-ApoE peptide carrier targeting the blood brain barrier
Yuanpeng Zhao
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
Zhongmin Zou
2019 - Vol. 6 p.359-366
Phospholipid and Triglyceride keep vortex-dispersed sulfur mustard analog as undissolved droplets which induce necrosis from nearby cells via declining mitochondrial membrane potential
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