Fundamental Toxicological Sciences

Paper Details

Fundamental Toxicological Sciences
Vol. 2 No. 6 December 21, 2015 p.239-243
Letter
Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains
  • Akira Naganuma (Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University / naganuma@m.tohoku.ac.jp)
Tsutomu Takahashi 1) 2) , Miyuki Iwai-Shimada 1) , Yukina Syakushi 1) , Min-Seok Kim 1) , Gi-Wook Hwang 1) , Nobuhiko Miura 3) , Akira Naganuma 1)
1) Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University , 2) Department of Environmental Health, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences , 3) Division of Health Effects Research, Japan National Institute of Occupational Safety and Health
Keywords: Methylmercury, Brain, Interleukin, IL-1β, IL-19
Abstracts

We examined the effect of methylmercury administration on expression of interleukin genes in brain of mice. We found that gene expression of IL-1β and IL-19 was increased in the brain after the administration of methylmercury.