Fundamental Toxicological Sciences

Paper Details

Fundamental Toxicological Sciences
Vol. 6 No. 3 April 04, 2019 p.75-79
Original Article
Age-dependent aggravation of oral malodor and periodontal disease in dogs
  • Kazutoshi Sugita (Laboratory of Veterinary Public Health-1, School of Veterinary Medicine, Azabu University / sugita@azabu-u.ac.jp)
Naoki Iwashita 1) , Kazutoshi Sugita 2) , Sayaka Murata 1) , Keiko Ichimura 1) , Mitsuyuki Shirai 1) , Masaharu Hisasue 3) , Miyoko Saito 4) , Takuma Aoki 5) , Yukihiko Takagi 2) , Fumitoshi Asai 1)
1) Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University , 2) Laboratory of Veterinary Public Health-1, School of Veterinary Medicine, Azabu University , 3) Laboratory of Veterinary Small Animal Internal Medicine, School of Veterinary Medicine, Azabu University , 4) Laboratory of Veterinary Surgery-2, School of Veterinary Medicine, Azabu University , 5) Laboratory of Veterinary Surgery-1, School of Veterinary Medicine, Azabu University
Keywords: Volatile sulfur compound, Portable gas chromatograph, Malodor, Periodontal disease, Dog
Abstracts

Halitosis or oral malodor is correlated with the concentration of volatile sulfur compounds (VSCs) produced in the oral cavity by metabolic activity of periodontal pathogenic germs. Our previous study demonstrated that VSCs in canine breath air can be measured using a portable VSC monitor. The aim of this study was to assess the association between oral malodor and periodontal disease in dogs. Forty-three laboratory Beagle dogs (1-16 years of age, 24 males, 19 females) were included in this study. Oral halitosis was evaluated by the organoleptic test score (OS) and by measuring the oral levels of VSCs: hydrogen sulfide (H2S; HS), methyl mercaptan (CH3SH; MM), and dimethyl sulfide (CH3SCH3; DMS) using OralChromaâ„¢. The calculus index (CI) and the gingival index (GI) were measured as periodontal parameters. Oral levels of halitosis parameters (OS, HS, MM, CI, and GI) in Group 2 dogs (7-16 years of age) were significantly higher than those in Group 1 dogs (1-6 years of age). In addition, significant positive relationships were found between oral malodor and periodontal disease, both of which are age-dependent in dogs. The present study suggested that aging is an important factor for oral malodor and periodontal disease in dogs.